Small Molecule Survivin Inhibitor YM155 Displays Potent Activity Against Human Osteosarcoma Cells

A phase I/II study of sepantronium bromide (YM155, survivin suppressor) with paclitaxel and carboplatin in patients with advanced non-small-cell lung cancer

(2013) R. J. Kelly et al.   ANNALS OF ONCOLOGY

Induction of autophagy-dependent cell death by the survivin suppressant YM155 in salivary adenoid cystic carcinoma

(2013) Yu-Fan Wang et al.   APOPTOSIS

Pharmacokinetics of sepantronium bromide (YM155), a small-molecule suppressor of survivin, in Japanese patients with advanced solid tumors: dose proportionality and influence of renal impairment

(2012) Yumiko Aoyama et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Mcl-1 downregulation by YM155 contributes to its synergistic anti-tumor activities with ABT-263

(2011) Haikuo Tang et al.   BIOCHEMICAL PHARMACOLOGY

Sensitization of Osteosarcoma Cell Line SaOS-2 to Chemotherapy by Downregulating Survivin

(2010) Jun Zou et al.   ARCHIVES OF MEDICAL RESEARCH

Broad spectrum and potent antitumor activities of YM155, a novel small-molecule survivin suppressant, in a wide variety of human cancer cell lines and xenograft models

(2010) Takahito Nakahara et al.   CANCER SCIENCE

TNF-α Induces Two Distinct Caspase-8 Activation Pathways

(2008) Lai Wang et al.   CELL

Effects of Survivin on cell proliferation and apoptosis in MG-63 cells in vitro

(2008) X LIANG et al.   CELL BIOLOGY INTERNATIONAL