Thermal and mechanical high-intensity focused ultrasound: perspectives on tumor ablation, immune effects and combination strategies

PD-1 Blockade Boosts Radiofrequency Ablation-Elicited Adaptive Immune Responses against Tumor

(2016) L. Shi et al.   CLINICAL CANCER RESEARCH

First clinical experience with a dedicated MRI-guided high-intensity focused ultrasound system for breast cancer ablation

(2016) Laura G. Merckel et al.   EUROPEAN RADIOLOGY

In vivoMR guided boiling histotripsy in a mouse tumor model evaluated by MRI and histopathology

(2016) Martijn Hoogenboom et al.   NMR IN BIOMEDICINE

Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade

(2016) N. McGranahan et al.   SCIENCE

Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential

(2015) Padmanee Sharma et al.   CELL

Towards a dosimetric framework for therapeutic ultrasound

(2015) Adam Shaw et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Histotripsy methods in mechanical disintegration of tissue: Towards clinical applications

(2015) Vera A. Khokhlova et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Radiotherapy and Immunogenic Cell Death

(2015) Encouse B. Golden et al.   SEMINARS IN RADIATION ONCOLOGY

Mechanical High-Intensity Focused Ultrasound Destruction of Soft Tissue: Working Mechanisms and Physiologic Effects

(2015) Martijn Hoogenboom et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

Immune Adjuvant Activity of Pre-Resectional Radiofrequency Ablation Protects against Local and Systemic Recurrence in Aggressive Murine Colorectal Cancer

(2015) Fumito Ito et al.   PLoS One

Cryoimmunotherapy with local co-administration of ex vivo generated dendritic cells and CpG-ODN immune adjuvant, elicits a specific antitumor immunity

(2014) Zoya Alteber et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Cancer Immunotherapy and Breaking Immune Tolerance: New Approaches to an Old Challenge

(2014) A. Makkouk et al.   CANCER RESEARCH

HLA ligandome tumor antigen discovery for personalized vaccine approach

(2013) Hans-Georg Rammensee et al.   Expert Review of Vaccines

The effect of high-intensity focused ultrasound treatment on immune function in patients with uterine fibroids

(2013) Xiaoyan Wang et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Image-guided Thermal Ablation of Tumors Increases the Plasma Level of Interleukin-6 and Interleukin-10

(2013) Joseph P. Erinjeri et al.   JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY

Cancer Genome Landscapes

(2013) B. Vogelstein et al.   SCIENCE

Exploiting the Mutanome for Tumor Vaccination

(2012) J. C. Castle et al.   CANCER RESEARCH

Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting

(2012) Hirokazu Matsushita et al.   NATURE

M-HIFU Inhibits Tumor Growth, Suppresses STAT3 Activity and Enhances Tumor Specific Immunity in a Transplant Tumor Model of Prostate Cancer

(2012) Xiaoyi Huang et al.   PLoS One

MR Thermometry Analysis of Sonication Accuracy and Safety Margin of Volumetric MR Imaging–guided High-Intensity Focused Ultrasound Ablation of Symptomatic Uterine Fibroids

(2012) Young-sun Kim et al.   RADIOLOGY

High-Intensity Focused Ultrasound Tumor Ablation Activates Autologous Tumor-Specific Cytotoxic T Lymphocytes

(2012) Ji-Zhu Xia et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

Immune Adjuvant Efficacy of CpG Oligonucleotide in Cancer Treatment Is Founded Specifically upon TLR9 Function in Plasmacytoid Dendritic Cells

(2011) S. Nierkens et al.   CANCER RESEARCH

Potent Induction of Tumor Immunity by Combining Tumor Cryoablation with Anti-CTLA-4 Therapy

(2011) R. Waitz et al.   CANCER RESEARCH

Elevated serum levels of heat shock protein 70 can be detected after radiofrequency ablation

(2011) Sebastian P. Haen et al.   CELL STRESS & CHAPERONES

More Than Just Tumor Destruction: Immunomodulation by Thermal Ablation of Cancer

(2011) Sebastian P. Haen et al.   Clinical & Developmental Immunology

Cavitation clouds created by shock scattering from bubbles during histotripsy

(2011) Adam D. Maxwell et al.   JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA

Thermal Ablation

(2011) Heather Webb et al.   SEMINARS IN ROENTGENOLOGY

Saponin-based adjuvants create a highly effective anti-tumor vaccine when combined with in situ tumor destruction

(2011) Martijn H. den Brok et al.   VACCINE

Boosting high-intensity focused ultrasound-induced anti-tumor immunity using a sparse-scan strategy that can more effectively promote dendritic cell maturation

(2010) Fang Liu et al.   Journal of Translational Medicine

Dendritic Cells Loaded with Ultrasound-Ablated Tumour Induce in vivo Specific Antitumour Immune Responses

(2010) Jian Deng et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

Enhancement of antitumor vaccine in ablated hepatocellular carcinoma by high-intensity focused ultrasound

(2010) Ying Zhang   WORLD JOURNAL OF GASTROENTEROLOGY

MRI-Guided Focused Ultrasound Surgery

(2009) Ferenc A. Jolesz   Annual Review of Medicine

Abrogation of Local Cancer Recurrence After Radiofrequency Ablation by Dendritic Cell-based Hyperthermic Tumor Vaccine

(2009) Qiong Liu et al.   MOLECULAR THERAPY

Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance

(2009) Michael R. Elliott et al.   NATURE

Route of Administration of the TLR9 Agonist CpG Critically Determines the Efficacy of Cancer Immunotherapy in Mice

(2009) Stefan Nierkens et al.   PLoS One

Increased infiltration of activated tumor-infiltrating lymphocytes after high intensity focused ultrasound ablation of human breast cancer

(2009) Pei Lu et al.   SURGERY

Shock-Induced Heating and Millisecond Boiling in Gels and Tissue Due to High Intensity Focused Ultrasound

(2009) Michael S. Canney et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

The effect of high intensity focused ultrasound treatment on metastases in a murine melanoma model

(2008) Yifei Xing et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Immunogenic cancer cell death: a key-lock paradigm

(2008) Antoine Tesniere et al.   CURRENT OPINION IN IMMUNOLOGY

Short-duration-focused ultrasound stimulation of Hsp70 expressionin vivo

(2008) D E Kruse et al.   PHYSICS IN MEDICINE AND BIOLOGY

Activation of Tumor-Infiltrating Antigen Presenting Cells by High Intensity Focused Ultrasound Ablation of Human Breast Cancer

(2008) Zhong-Lin Xu et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

Changes in Circulating Immunosuppressive Cytokine Levels of Cancer Patients After High Intensity Focused Ultrasound Treatment

(2007) Qiang Zhou et al.   ULTRASOUND IN MEDICINE AND BIOLOGY