Age-associated impairment of antitumor immunity in carcinoma-bearing mice and restoration by oral administration of Lentinula edodes mycelia extract

IL-6-mediated environmental conditioning of defective Th1 differentiation dampens antitumour immune responses in old age

(2015) Hirotake Tsukamoto et al.   Nature Communications

Blockade of Fas Signaling in Breast Cancer Cells Suppresses Tumor Growth and Metastasis via Disruption of Fas Signaling-initiated Cancer-related Inflammation

(2014) Qiuyan Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adiposity induces lethal cytokine storm after systemic administration of stimulatory immunotherapy regimens in aged mice

(2014) Annie Mirsoian et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Subsets of Myeloid-Derived Suppressor Cells in Tumor-Bearing Mice

(2014) J.-I. Youn et al.   JOURNAL OF IMMUNOLOGY

Cross-talk among myeloid-derived suppressor cells, macrophages, and tumor cells impacts the inflammatory milieu of solid tumors

(2014) Daniel W. Beury et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Aging predisposes to acute inflammatory induced pathology after tumor immunotherapy

(2013) Myriam N. Bouchlaka et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Myeloid-Derived Suppressor Cells Attenuate TH1 Development through IL-6 Production to Promote Tumor Progression

(2013) H. Tsukamoto et al.   Cancer Immunology Research

Combining a peptide vaccine with oral ingestion of Lentinula edodes mycelia extract enhances anti-tumor activity in B16 melanoma-bearing mice

(2012) Kousuke Tanaka et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Tumor-induced myeloid-derived suppressor cell function is independent of IFN-γ and IL-4Rα

(2012) Pratima Sinha et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Aging-associated B7-DC+B cells enhance anti-tumor immunity via Th1 and Th17 induction

(2011) Kei Tomihara et al.   AGING CELL

Oral ingestion of Lentinula edodes mycelia extract inhibits B16 melanoma growth via mitigation of regulatory T cell-mediated immunosuppression

(2011) Kousuke Tanaka et al.   CANCER SCIENCE

Differential sensitivity to endotoxin exposure in young and middle-age mice

(2009) Rachel A. Kohman et al.   BRAIN BEHAVIOR AND IMMUNITY

Cancer, aging and immunotherapy: lessons learned from animal models

(2009) Joseph Lustgarten   CANCER IMMUNOLOGY IMMUNOTHERAPY

Immunogenic chemotherapy with cyclophosphamide and doxorubicin against established murine carcinoma

(2009) Miki Tongu et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Myeloid-Derived Suppressor Cells: Linking Inflammation and Cancer

(2009) S. Ostrand-Rosenberg et al.   JOURNAL OF IMMUNOLOGY

Structural analysis of glycogen-like polysaccharides having macrophage-activating activity in extracts of Lentinula edodes mycelia

(2009) Hiroaki Kojima et al.   Journal of Natural Medicines

Immunogenic cancer cell death: a key-lock paradigm

(2008) Antoine Tesniere et al.   CURRENT OPINION IN IMMUNOLOGY