Article
Spectroscopy
Mingchun Lv, Hongbin Pu, Da-Wen Sun
Summary: This study constructed a new SERS substrate Fe3O4@UiO-66(Zr)@Ag nanoparticles (FUAs) with excellent SERS detection sensitivity, uniformity, reproducibility, and stability. It exhibited a high Raman enhancement factor (5.62 x 106), low limit of detection (LOD, 2.11 x 10-11 M), and RSD (12.41%) for 4-NBT, while maintaining 81% SERS activity within 60 days. FUAs took advantage of the strong affinity of UiO-66(Zr) for organophosphorus pesticides (OPs) to achieve trace OPs detection, showing potential for detecting OPs in foods.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Engineering, Environmental
Jiajia Huang, Lei Jiao, Weiqing Xu, Hengjia Wang, Meng Sha, Zhichao Wu, Wenling Gu, Liuyong Hu, Chengzhou Zhu
Summary: Cell-free enzymatic catalysis (CFEC) is a promising biotechnology that simulates biological transformations without living cells, but the high cost and difficulty in enzyme separation and preparation hinder its practical application. Enzyme immobilization technologies using solid supports are considered an efficient strategy to address this issue, but the activity and stability of immobilized enzymes remain crucial challenges for in vitro applications.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Engineering, Environmental
Dali Wei, Mingwei Li, Ying Wang, Nuanfei Zhu, Xialin Hu, Biying Zhao, Zhen Zhang, Daqiang Yin
Summary: This study designed GSH-Au NCs@ZIF-8 by encapsulating GSH-Au NCs with AIE effect into metal-organic frameworks, achieving high luminescence efficiency and good stability. A fluorescent sensing platform was constructed for the sensitive detection of copper ions and organophosphorus pesticides. Furthermore, a hydrogel sensor was explored for equipment-free, visual, and quantitative monitoring of copper ions and organophosphorus pesticides using a smartphone sensing platform.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Chemistry, Analytical
Zhikun Zhang, Liu Zhang, Ping Han, Qingju Liu
Summary: Terbium-based metal-organic frameworks were used to construct a fluorescence probe for the detection of organophosphorus pesticides. The method showed high sensitivity and selectivity, and was successfully applied to the analysis of tap water and strawberry samples.
Article
Chemistry, Applied
Fei Tong, Zan Yang, Zheng Wang, Wenya Liu, Wanqi Jiang, Lu Zhu, Lei Wang, Mingming Zheng, Ruyan Hou, Yibin Zhou, Yingnan Liu
Summary: This paper constructed a ratiometric fluorescent probe using a functionalized metal-organic framework to detect the potential hazards of organophosphorus pesticides (OPs). The probe achieved linear responses to dichlorvos and chlorpyrifos with low detection limits. Additionally, a hydrogel detection platform was developed to enhance the detection of OPs in agricultural products.
Article
Nanoscience & Nanotechnology
Jingwen Feng, Jinjuan Gao, Wen Yang, Yaru Li, Jian Shi, Cong Liu, Mingshun Jiang, Shouzhen Jiang
Summary: A 2D Cu-TCPP MOF nanosheet-capsulated Au film structure was developed for sensitive and selective detection of dopamine with small changes in refractive index. The experimental results showed that the sensitivity and figure of merit were notably increased compared to the bare Au film. Numerical analysis confirmed the excellent charge-transfer ability and bidirectional gain properties between the MOF nanosheets and Au film. The biosensor demonstrated enhanced sensitivity and selectivity for dopamine detection, making it a promising platform for clinical diagnosis and medical assessment.
ACS APPLIED NANO MATERIALS
(2023)
Article
Engineering, Electrical & Electronic
Xiaoling Peng, Zhicong Ren, Changhai Lu, Penglai Guo, Weicheng Chen, Daotong You, Kaiwei Li, Tuan Guo, Gaozhi Xiao, Jianqing Li
Summary: A hybrid electrochemical-surface plasmon resonance (SPR) microfiber sensor is proposed for sensitive detection of Pb2+. The sensor utilizes a gold-coated indium tin oxide (ITO) working electrode and a gold nanofilm-coated microfiber to monitor the electrochemical reaction process in real time. The microfiber-based SPR sensor is capable of detecting slight refractive index changes on the surface and can provide voltage, current, and optical information simultaneously. This dual-modal detection method offers a broad detection range and a low limit of detection, making it suitable for accurate and intuitive heavy metal ion detection in various environments.
JOURNAL OF LIGHTWAVE TECHNOLOGY
(2023)
Article
Chemistry, Physical
Chuanping Li, Shuoren Li, Tianxiang Hang, Feifei Guo, Xian-Dong Zhu, Tian-Fu Liu
Summary: This study designed a plasmon-enhanced catalyst by integrating metal-organic frameworks (MOFs)-derived Cd0.8Zn0.2S with Ag/Au hollow porous nanoshells (Ag/Au HPNSs), which extends the spectral absorption range and improves the performance of photoelectrochemical (PEC) water splitting. Theoretical simulations showed that MOFs-derived Cd0.8Zn0.2S with a high dielectric constant can prevent the decay of plasmon fringing field and enhance charge separation efficiency.
Article
Chemistry, Multidisciplinary
Wenbo Wei, Shenghua Zhou, Dong-Dong Ma, Qing Li, Maoyin Ran, Xiaofang Li, Xin-Tao Wu, Qi-Long Zhu
Summary: Ultrathin nitrogen and sulfur-rich bithiazole-based COF nanosheets (COF-Bta-NSs) were developed for constructing high-performance biosensors by integrating with acetylcholinesterase (AChE) through strong supramolecular interactions. These biosensors exhibited excellent electrical conductivity and abundant edge unsaturated sites, enabling the detection of various organophosphorus pesticides with a wide detection range, ultralow detection limit, and high stability. A portable biosensing device based on commercialized screen-printed electrode (SPE) was also established, demonstrating sensitive and reliable detection of actual samples from river water and leafy vegetables.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Biochemistry & Molecular Biology
Minwen Sun, Wei Xu, Wenli Zhang, Cuie Guang, Wanmeng Mu
Summary: In this study, the researchers prepared a metal-organic framework (MOF) MIL-88A and used it as a carrier for immobilizing the methyl parathion hydrolase from Azohydromonas australica (Azau-MPH). The immobilized Azau-MPH showed higher activity and better storage stability compared to the free enzyme. It also exhibited a high reuse efficiency and sensitivity for detecting methyl parathion.
PROCESS BIOCHEMISTRY
(2022)
Article
Engineering, Environmental
Guang Li, Han Zhang, Sai Yan, Hengxue Xiang, Huidan Wei, Yuhan Xia, Xunda Feng, Ran Cao, Meifang Zhu
Summary: Wearable electronics have become versatile platforms for various biomedical applications. However, the development of sensors that are both air-permeable and highly sensitive for long-term physiological signal monitoring is still challenging. An innovative in-situ growth method was used to enhance the sensitivity of electrospun polyvinylidene fluoride (PVDF) nanofibers by decorating them with a zeolitic imidazolate framework (ZIF-8). The resulting sensor showed a significant increase in sensitivity compared to sensors made with pure PVDF nanofiber, making it promising for the development of highly sensitive and skin-friendly wearable electronics.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Analytical
Li Hou, Xiaoyu Chen, Xuanhan Zhang, Yufang Tang, Yiyun Yao, Tianran Lin, Shulin Zhao
Summary: A colorimetric method for the hydrolysis of profenofos was developed using Zn-ZrMOF as a catalyst. The method utilizes the cleavage of the P-O bond of profenofos to produce 4-bromo-2-chlorophenol, which reacts with the chromogenic agent 4-amino-antipyrine to form a pink product. The concentration of profenofos can be semi-quantitatively analyzed by observing the color change of the solution.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Chemistry, Analytical
Behnaz Hatamluyi, Samira Sadeghzadeh, Majid Rezayi, Seyedeh Belin Tavakoly Sany
Summary: A simple platform was designed for accurate detection of diazinon, a widely used pesticide, using an engineered zeolitic imidazolate framework (ZIF) immobilized with an aptamer. The platform showed high sensitivity and low detection limit, with recovery rates indicating its feasibility and reliability in analyzing diazinon in different samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Chemistry, Multidisciplinary
Chen Wang, Heyao Zhang, Yao Wang, Jie Wu, Kent O. Kirlikovali, Peng Li, Yaming Zhou, Omar K. Farha
Summary: A general and efficient strategy is reported for the synthesis of inverse opal metal-organic frameworks (IO MOFs) with tunable macro-, meso-, and micro-pores. These materials demonstrate improved adsorption and hydrolysis performance for organophosphorus aggregates.
Article
Chemistry, Analytical
Chenyang He, Liangliang Liu, Sergiy Korposh, Ricardo Correia, Stephen P. Morgan
Summary: A tip-based fiber optic localized surface plasmon resonance (LSPR) sensor is developed for detecting volatile organic compounds (VOCs) by coating the tip with gold nanoparticles and further functionalizing with HKUST-1 metal-organic framework. The sensitivity and response time of the sensor are influenced by the thickness of the MOF film and different cycles of coating. The sensor with 120 coating cycles shows higher sensitivity and reversible response to VOCs, with a limit of detection (LoD) of 0.005%-0.011% for acetone, ethanol, and methanol measurements.
Article
Nanoscience & Nanotechnology
Vladislav Buravets, Frantisek Hosek, Ladislav Lapcak, Elena Miliutina, Petr Sajdl, Roman Elashnikov, Vaclav Svorcik, Oleksiy Lyutakov
Summary: In this study, a novel, simple, and scalable method for the synthesis of tantalum disulfide (TaS2) is reported, using CS2 as a sulfurizing agent and Ta2O5 as a metal precursor. The structure of the created TaS2 flakes was analyzed, and a tuning between 1T (metallic) and 3R (semiconductor) phases was achieved by varying the reaction conditions. The electrocatalytic activity of the synthesized materials was significantly enhanced after electrochemical self-activation, reaching a level comparable to that of Pt. This work provides a scalable and simple synthesis method for transition-metal sulfides that could replace platinum catalysts in water splitting technology.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Applied
Yulia A. Vlasenko, Thomas J. Kuczmera, Nikita S. Antonkin, Rashid R. Valiev, Pavel S. Postnikov, Boris J. Nachtsheim
Summary: Here, the application of azole-stabilized diaryliodonium salts with additional thiophene-2-yl-ligands as metal-free nucleophilic arylation substrates is presented. In addition to their synthesis, their use in chemoselective nitrations, oxygenations, aminations, and thiolations under umpolung conditions is demonstrated. Convenient one-pot procedures based on their in situ formation are also discussed.
ADVANCED SYNTHESIS & CATALYSIS
(2023)
Article
Engineering, Environmental
Anna Zabelina, Elena Miliutina, Denis Zabelin, Vasilii Burtsev, Vladislav Buravets, Roman Elashnikov, Viktorie Neubertova, Martin St'astny, Daniela Popelkova, Jan Lancok, Sergii Chertopalov, Martin Paidar, Andrii Trelin, Alena Michalcova, Vaclav Svorcik, Oleksiy Lyutakov
Summary: Hybridization of catalytic and plasmon active materials is proposed to efficiently improve photo-electrochemical (PEC) water splitting. The plasmon coupling between surface plasmon polariton (SPP) and localized surface plasmon (LSP) is utilized to achieve gigantic light concentration and trigger the catalytic activity of titanium diboride (TiB2) flakes. The catalytic activity enhancement of TiB2 flakes through coupled plasmon triggering is investigated in various conditions, showing the excitation of electron-hole pairs and their separation/acceleration in strong plasmons field. This work presents a novel approach for realizing a symmetric and less pH-sensitive catalyst for PEC water splitting.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Organic
Ekaterina V. Podrezova, Alina A. Okhina, Artem D. Rogachev, Sergey V. Baykov, Andreas Kirschning, Mekhman S. Yusubov, Natalia S. Soldatova, Pavel S. Postnikov
Summary: In this study, a method for the copper-catalyzed N-arylation of hindered oxazolidinones using diaryliodonium salts was described. The method exhibited good to excellent yields for the arylation of 4-alkyloxazolidinones, including sterically hindered isopropyl- and tert-butyl-substituted ones. The method was efficient for a wide range of diaryliodonium salts - symmetric and unsymmetric as well as ortho-substituted derivatives. The developed approach will make an important contribution to the development and preparation of novel drugs and bioactive molecules containing oxazolidinone moieties.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2023)
Article
Chemistry, Physical
Dmitry Kogolev, Oleg Semyonov, Nadezhda Metalnikova, Maxim Fatkullin, Raul D. D. Rodriguez, Petr Slepicka, Yusuke Yamauchi, Olga Guselnikova, Rabah Boukherroub, Pavel S. S. Postnikov
Summary: We propose utilizing laser-assisted carbonization of surface-grown UiO-66 to diversify the upcycling of waste PET into materials with enhanced photothermal properties. A solvo-thermal procedure was used to form a homogeneous UiO-66 layer on recycled PET sheets. Treatment with a 405 nm laser system enabled the formation of a carbonaceous layer with improved electrical conductivity and photothermal properties due to the presence of zirconium carbide and graphene. This approach presents new possibilities for the application of upcycled PET-based materials.
JOURNAL OF MATERIALS CHEMISTRY A
(2023)
Article
Chemistry, Physical
Olga Guselnikova, Roman Elashnikov, Vaclav Svorcik, Martin Kartau, Cameron Gilroy, Nikolaj Gadegaard, Malcolm Kadodwala, Affar S. S. Karimullah, Oleksiy Lyutakov
Summary: The use of surface enhanced Raman scattering (SERS) combined with disposable chiral plasmonic shurikens and silver nanoclusters allows for effective detection and discrimination of chiral compounds with high sensitivity. Numerical simulations were used to study the effects of shuriken geometry, silver nanostructured layer parameters, and SERS excitation wavelength(s) on the observed SERS response. The designed structures were able to successfully discriminate cysteine enantiomers and probe biomolecular chirality using a standard Raman spectrometer.
NANOSCALE HORIZONS
(2023)
Article
Chemistry, Physical
Anastasia Skvortsova, Alzbeta Kocianova, Olga Guselnikova, Roman Elashnikov, Vasilii Burtsev, Silvie Rimpelova, Vladimira Svobodova Pavlickova, Premysl Fitl, Miroslava Lukesova, Zdenka Kolska, Vaclav Svorcik, Oleksiy Lyutakov
Summary: In this study, an intelligent self-activating antibacterial coating was proposed to prevent bacterial colonization and biofilm formation on the surface of medically-relevant polypropylene (PP). The coating, which is covalently immobilized with a metal-organic framework structure (CuBTC), can release NO center dot radicals from its endogenous donor in response to increasing concentration of GSNO in body fluids. This coating can effectively inhibit bacterial adhesion and be self-activated at the right place and time.
APPLIED SURFACE SCIENCE
(2023)
Article
Chemistry, Multidisciplinary
Irina I. Fedorova, Natalia S. Soldatova, Daniil M. Ivanov, Ksenia Nikiforova, Irina S. Aliyarova, Mekhman S. Yusubov, Peter M. Tolstoy, Rosa M. Gomila, Antonio Frontera, Vadim Yu. Kukushkin, Pavel S. Postnikov, Giuseppe Resnati
Summary: This study reports the planarity of the benzothienoiodolium cation and the preorganization it provides for the hydrogen, halogen, and chalcogen bonds formed by the phenyl hydrogen, iodolium iodine, and thienyl sulfur. Crystallographic analysis reveals the coupling of these bonds to a single anion, coordinated via the supramolecular and heteroditopic synthon XB/HB or XB/ChB. The interactions of these synthons act synergistically and result in unusually short chalcogen bonds formed by the thienyl sulfur.
CRYSTAL GROWTH & DESIGN
(2023)
Article
Chemistry, Inorganic & Nuclear
Artem V. Semenov, Sergey V. Baykov, Natalia S. Soldatova, Kirill K. Geyl, Daniil M. Ivanov, Antonio Frontera, Vadim P. Boyarskiy, Pavel S. Postnikov, Vadim Yu. Kukushkin
Summary: Five new copper(I) complexes were generated and isolated as a solid via a three-component reaction. These complexes consist of dibenzohalolium cation and 1,2,4-oxadiazolate anion, with simultaneous linkage between the O,O atoms of the anion and the halogen atom. The strong three-center halogen bonding between the oxadiazolate moieties and the dibenzohalolium cation was identified as the main force in stabilizing the copper(I) complexes.
INORGANIC CHEMISTRY
(2023)
Article
Chemistry, Physical
Darya Votkina, Pavel Petunin, Elena Miliutina, Andrii Trelin, Oleksiy Lyutakov, Vaclav Svorcik, Gerard Audran, Jeffrey Havot, Rashid Valiev, Lenara I. Valiulina, Jean-Patrick Joly, Yusuke Yamauchi, Junais Habeeb Mokkath, Joel Henzie, Olga Guselnikova, Sylvain R. A. Marque, Pavel Postnikov
Summary: The local surface plasmon resonances of gold nanoparticles can provide alternative pathways for organic chemical reactions. The role of chemical factors associated with organic reactants, such as molecular structure and electronic effects, is often underestimated. In this study, we synthesized alkoxyamines with different structures and used spectroscopy to investigate the kinetics of plasmon-induced homolysis. The results show that the intramolecular excitation mechanism plays a key role in plasmon-induced homolysis, which suggests that electronic structures may also be important in other plasmon catalysis reactions.
Article
Materials Science, Multidisciplinary
Martin Kartau, Anastasia Skvortsova, Victor Tabouillot, Shailendra K. Chaubey, Polina Bainova, Rahul Kumar, Vasilii Burtsev, Vaclav Svorcik, Nikolaj Gadegaard, Sang Won Im, Marie Urbanova, Oleksiy Lyutakov, Malcolm Kadodwala, Affar S. Karimullah
Summary: Chiral nanophotonic platforms enhance both the asymmetric properties and intensities of near fields, enabling optical measurements with enantiomeric discrimination at a higher detection level than conventional chirally sensitive spectroscopic methods. This study demonstrates the use of surface enhanced Raman spectroscopy (SERS) as a local probe to discriminate chiral helicoid nanoparticles on chiral metafilms. The intensity of electromagnetic hotspots generated by matched combinations of helicoid and metafilms is higher, while mismatched combinations result in cooler electromagnetic hotspots. SERS is used to detect the enantiomeric dependency of hotspot intensity, allowing the distinction between different electromagnetic environments of plasmonic diastereomers.
ADVANCED OPTICAL MATERIALS
(2023)
Review
Chemistry, Multidisciplinary
Olga Guselnikova, Oleg Semyonov, Elizaveta Sviridova, Roman Gulyaev, Alina Gorbunova, Dmitry Kogolev, Andrii Trelin, Yusuke Yamauchi, Rabah Boukherroub, Pavel Postnikov
Summary: Diversification of polymer waste recycling, specifically through functional upcycling, is a promising strategy for improving the current environmental scenario. This review explores the methods and characteristics of upcycling polymer waste into new materials with enhanced functionality, highlighting the composition of plastic waste, reactivity, modification agents, and the application of the resulting upcycled materials. The reviewed reports demonstrate that upcycled materials exhibit high added value and comparable or higher performance than materials produced from virgin polymer feedstock. Comparative analysis with chemical and mechanical recycling identifies the advantages of functional upcycling and suggests directions for future research.
CHEMICAL SOCIETY REVIEWS
(2023)
Article
Materials Science, Multidisciplinary
Roman Gulyaev, Oleg Semyonov, Georgy V. Mamontov, Alexey A. Ivanov, Daniil M. Ivanov, Minjun Kim, Vaclav Svorcik, Giuseppe Resnati, Ting Liao, Ziqi Sun, Yusuke Yamauchi, Pavel S. Postnikov, Olga Guselnikova
Summary: This study demonstrates the potential of halogen bonding (HaB) in functional materials for separation science, by introducing HaB elements into UiO-66 to fine-tune the adsorption properties towards chlorobenzenes (CBs).
ACS MATERIALS LETTERS
(2023)
Article
Chemistry, Analytical
Qian Wu, Li Tian, Xiangyu Shan, Huiling Li, Chao Li, Juan Lu
Summary: A novel ECL sensor was developed by modifying Fe3CuO4-Ru(bpy)3+ and GO-CdS@ZnS on the electrode for the detection of permethrin. The sensor exhibited high sensitivity and a wide detection range.
Article
Chemistry, Analytical
Tingting Gong, Lei Liao, Bingying Jiang, Ruo Yuan, Yun Xiang
Summary: In this study, a fluorescent biosensing system for high sensitivity detection of MT was established using a new Ag+-stabilized DNA triplex probe (Ag+-SDTP) combined with catalytic hairpin assembly (CHA) and CRISPR/Cas12a signal enhancements. The sensing method is able to selectively detect MT from other non-specific molecules and can achieve low level detection of MT in diluted human serums, demonstrating its potential for monitoring disease-specific MT biomarker at trace levels.
Article
Chemistry, Analytical
Estrella Sanz Rodriguez, Kyra Wood, Paul R. Haddad, Brett Paull
Summary: This study presents a simple, rapid, and reliable method for determining boron in aqueous solutions using suppressed ion chromatography coupled to electrospray ionisation-triple quadrupole mass spectrometry. The method achieved a low limit of detection and demonstrated excellent analytical performance.
Article
Chemistry, Analytical
Aline Cournut, Paul Moustiez, Yannick Coffinier, Christine Enjalbal, Claudia Bich
Summary: Alzheimer's disease is a major cause of senile dementia and is characterized by the aggregation of neurofibrillary tangles and amyloid plaques in the brain. The A beta 1-42 peptide is considered the primary cause of neurotoxicity due to its insolubility and subsequent aggregation. A beta 1-42 and A beta 1-40 have been identified as relevant biomarkers for AD diagnosis, and SurfaceAssisted Laser Desorption/Ionization Mass Spectrometry (SALDI-MS) was used to monitor the A beta 1-42/A beta 1-40 ratio without prior sample treatment.
Article
Chemistry, Analytical
Dotse Selali Chormey, Buse Tugba Zaman, Tulay Borahan Kustanto, Sezin Erarpat Bodur, Suleyman Bodur, Elif Ozturk Er, Sezgin Bakirdere
Summary: This review provides an overview of the harmful effects of endocrine disrupting chemicals (EDCs) on human health and introduces the methods for analyzing EDCs. Recent research has focused on using green chemicals, such as deep eutectic solvents (DESs), for microextraction to ensure environmental safety.
Article
Chemistry, Analytical
Yan Zhang, Renfeng Xu, Jingjing Wu, Zhenghong Zhang, Yuhuang Wang, Hongqin Yang, Sheng Zhang
Summary: This study visualized the pore-like structures in prostate cancer cell membranes after treatment with the anticancer drug paclitaxel, demonstrating its mechanism of action related to oxidative damage.
Article
Chemistry, Analytical
Chihong Ma, Qin Zhou, Jinjin Shi, Hua Gao, Di Huang, Huimin Xue, Han Wang, Zhenzhong Zhang, Sen Yang, Junli Zhang, Kaixiang Zhang
Summary: We developed a CRISPR-empowered electrochemical biosensor, named PER-E-CRISPR, for amplification-free and sensitive detection of miR-21. The biosensor combines the advantages of CRISPR/Cas13a and primer exchange reaction (PER) for target amplification. Under optimized conditions, the PER-E-CRISPR assay exhibits a linear range from 10-13 to 10-7 M and a limit of detection of 30.2 fM. The biosensor shows excellent performance in actual plasma, indicating promising prospects for miRNA detection in molecular diagnosis.
Article
Chemistry, Analytical
Gang Liang, Jie Zhao, Yufei Gao, Tao Xie, Jianhui Zhen, Ligang Pan, Wenwen Gong
Summary: Molecular docking (MD) analysis is widely used for studying the interaction between aptamers and small molecules. This study established steady-state aptamers of tertiary structures (SATS) using specific aptamers of tetracycline antibiotics as docking models. Molecular docking results revealed multiple binding sites in the SATS of aptamers, with significant variations in binding free energy (BFE) and docking score (DS). The study also proposed a method for MD analysis based on SATS, providing insights into binding mode and predicting binding sites.
Article
Chemistry, Analytical
Yixuan Xu, Changchang Teng, Huiping Dang, Dalong Yin, Lifeng Yan
Summary: Stable organic radical molecules with high NIR fluorescence quantum efficiency have been synthesized and encapsulated into nanoparticles, which show great potential for both photodynamic therapy (PDT) and photothermal therapy (PTT) of tumors.
Article
Chemistry, Analytical
Yu Su, Dandan Yang, Yanjie Wang, Jie Ding, Lan Ding, Daqian Song
Summary: In this study, a highly selective molecularly imprinted polymer Cu-MIPs@CS was designed and synthesized for bisphenol A (BPA). Cu-MIPs@CS showed significantly enhanced imprinting factor and selective factor towards BPA compared to MIPs@CS. It also exhibited superior discrimination ability between BPA and its structural analogue. Additionally, Cu-MIPs@CS were successfully applied as a solid phase extraction adsorbent for the determination of BPA in drinking water samples.
Article
Chemistry, Analytical
Yi Qiao, Qiongdan Zhang, Yukun He, Tianguang Cheng, Jing Tu
Summary: Single cell heterogeneity plays an important role in many biological phenomena, and distinguishing cells with specific mutations is beneficial for clinical diagnosis and drug screening. This study introduces a gel plate platform that can distinguish cell types based on their phenotypes, with low equipment requirement. The gel platform has potential in point-of-care circumstances and single-cell stimulation responses that prioritize efficiency and simplicity.
Article
Chemistry, Analytical
Chengke Wang, Shuyang Sun, Ping Wang, Huawei Zhao, Wenling Li
Summary: The food safety of aquatic products is a global concern. Nanotechnology-based analyses have advantages in the detection of bacteria, metal ions, and small molecule contaminants. This review summarizes the recent advances in biosensing strategies for aquatic products and highlights the application of nanomaterials, lateral flow-based biosensors, surface-enhanced Raman scattering, microfluidic chips, and molecular imprinting technologies.
Article
Chemistry, Analytical
Liping Zhu, Zeng Tang, Xuemei Zhang, Li Zhu, Tian Meng, Linying Yu, Ting Xiao, Shasha Lu, Xiaoli Xiong, Xiurong Yang
Summary: A sensitive off-on electrochemiluminescence DNA sensor was developed using Exo III-assisted cascade amplification system. The sensor achieved high selectivity and ultra-high sensitivity in detecting target DNA by utilizing ECL and SPR effects. This study provides a new perspective for designing highly sensitive and programmable ECL biosensors.
Article
Chemistry, Analytical
Tong Li, Mengxu Sun, Suping Xia, Ting Huang, Rong-Tian Li, Chunrong Li, Zong Dai, Jin-Xiang Chen, Jun Chen, Nuan Jia
Summary: Here, we developed a binary system based on DNA tetrahedron and fluorogenic RNA aptamers for highly specific and label-free mRNA imaging in living cells. This system achieved high specificity label-free detection of nucleic acids with a detection limit of 1.34 nM. The method has potential applications in early disease diagnosis and new drug development.
Article
Chemistry, Analytical
Yao Zhao, Shu Zhang, Wang Yao, Yuxuan Zhu, Jing Qian, Juan Yang, Nianjun Yang
Summary: A new hierarchical nanostructured composite with high conductivity and catalytic activity is synthesized. The sensor exhibits significant catalytic effect and high sensitivity for monitoring the environmental endocrine disruptor bisphenol A (BPA).
