Article
Biochemistry & Molecular Biology
Hsia-Wei Liu, Wen-Ta Su, Ching-Yi Liu, Ching-Cheng Huang
Summary: A gelatin-based hydrogel scaffold with highly uniform pore size and biocompatibility was fabricated for cartilage tissue engineering using microfluidic 3D-foaming technology. The results showed that the scaffold has great potential in promoting chondrocyte proliferation, maintaining the structural stability of cartilage, and promoting cartilage repair.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Multidisciplinary Sciences
Mariliis Klaas, Kaidi Moll, Kristina Maemets-Allas, Mart Loog, Martin Jarvekulg, Viljar Jaks
Summary: Solution blow spinning (SBS) combined with gelatin is an effective method to generate nano- and microfiber structures suitable for tissue engineering. 3D gelatin scaffolds generated by SBS were used as culturing substrates for creating 3D human liver tissue equivalents in 96-well format, supporting hepatocyte-specific gene expression and maintaining hepatocyte differentiation and polarization status in long term cultures.
SCIENTIFIC REPORTS
(2021)
Article
Polymer Science
Junli Shi, Hang Yao, Bowen Wang, Jian Yang, Dianwei Liu, Xianfeng Shang, Hui Chong, Wenyong Fei, Dong-An Wang
Summary: Interface tissue repair requires the development of biomaterials with integrated structures of multiple protein types. In this study, gelatin methacrylate (GelMA) hydrogel is used to encapsulate chondrocytes and create micropores, allowing for the formation of bioactive extracellular matrix proteins. The decellularized tissue-engineered extracellular matrix and GelMA hydrogel interpenetrating network hydrogel (dECM-GelMA IPN) formed in this study has the potential to mediate the repair and regeneration of tendon-bone interface tissues with multiple protein types. This research provides a new solution for interface tissue repair.
MACROMOLECULAR RAPID COMMUNICATIONS
(2023)
Article
Engineering, Electrical & Electronic
Panagiotis Kassanos, Florent Seichepine, Guang-Zhong Yang
Summary: This article discusses the challenges with commercial benchtop impedance analyzers in accurately measuring tetrapolar bio-impedance due to large electrode contact impedances, proposing that external front-end amplifiers can help overcome this issue. Comparison is made between various discrete component-based topologies and new alternatives to evaluate their performance in measuring known loads in bio-impedance measurements. Ultimately, one of the best performing amplifiers is identified for use in practical applications and material/sensor characterization.
IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT
(2021)
Article
Food Science & Technology
Xiaohong Chen, Linzi Li, Lin Chen, Wei Shao, Yan Chen, Xiaojing Fan, Yaping Liu, Changbo Tang, Shijie Ding, Xinglian Xu, Guanghong Zhou, Xianchao Feng
Summary: This study aimed to construct block-shaped cell culture meat by using edible scaffolds as a platform for animal stem cell expansion. The tea polyphenols (TP)-coated 3D scaffolds, composed of sodium alginate (SA) and gelatin (Gel), showed good biocompatibility and mechanical support. Rabbit skeletal muscle myoblasts exhibited good adhesion and extension behavior on the TP-coated scaffolds with high expression of myogenic differentiation proteins and genes. The scaffolds with TP coating significantly improved cell proliferation rate and morphology, indicating their high potential for cultured meat production.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Biotechnology & Applied Microbiology
Sorel E. De Leon, Lana Cleuren, Zay Yar Oo, Paul R. Stoddart, Sally L. McArthur
Summary: Three-dimensional cell cultures are being used as tools for biologically modeling the human body, requiring sensitive characterization techniques such as impedance spectroscopy. The nature and distribution of cells within the 3D culture, as well as the architecture of the electrodes, are key variables affecting the impedance signal at different frequencies.
BIOENGINEERING-BASEL
(2021)
Article
Chemistry, Physical
Markus Merk, Orlando Chirikian, Christian Adlhart
Summary: Recent advancements have led to the creation of highly porous three-dimensional nanofiber scaffolds using electrospinning and self-assembly techniques for various tissue engineering applications. These scaffolds, made of biologically relevant materials, exhibit excellent mechanical properties and cell cytocompatibility, showing great potential for future tissue engineering applications.
Article
Polymer Science
Pablo Edmundo Antezana, Sofia Municoy, Gorka Orive, Martin Federico Desimone
Summary: The development of new materials is necessary in the medical field to replace damaged organs, improve wound healing, and provide an environment for new healthy tissue formation. This study introduced a bioink made with gelatin and alginate, which was 3D printed using an extrusion bioprinter. The bioink was loaded with Cannabis sativa oil extract, providing antimicrobial and antioxidant properties. This new biocompatible material has the potential to be an attractive alternative for treating soft-tissue infections and wound repair.
Article
Chemistry, Multidisciplinary
Graziella Scandurra, Antonella Arena, Emanuele Cardillo, Gino Giusi, Carmine Ciofi
Summary: Electrical Impedance Spectroscopy (EIS) is a characterization technique that is gaining importance in various fields. This study focuses on designing, implementing, and testing a low frequency impedance measurement platform that is portable, affordable, and versatile.
APPLIED SCIENCES-BASEL
(2021)
Article
Biochemistry & Molecular Biology
Yunsheng Dong, Hui Xiao, Jie Wang, Tingting Yang, Naiqi Kang, Jiaxing Huang, Wei Cui, Yufei Liu, Qiang Yang, Shufang Wang
Summary: Constructing scaffolds with osteogenic activity through tissue engineering is an effective strategy for bone regeneration. This study used gelatin, silk fibroin, and Si3N4 to prepare silicon-functionalized bio-macromolecules composite scaffolds using 3DP technology. The scaffold showed good cyto-compatibility and promoted osteogenic differentiation of MSCs in vitro, and facilitated bone regeneration in vivo. The composite scaffold system has great potential for application in bone tissue engineering.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Engineering, Biomedical
Steffen Novik, Magnus Flo Drageseth, Magnus Borresen Grondalen, Ola Nilsen, Stefan Johannes Karl Krauss, Orjan Grottem Martinsen, Philipp Dominik Hafliger
Summary: This paper demonstrates the implementation of a multi-electrode array for four-electrode bioimpedance measurements on a CMOS chip. By designing and fabricating an 8x8 pixel array along with dedicated amplifiers, the functionality of the chip in measuring differential voltages and currents is successfully demonstrated.
IEEE TRANSACTIONS ON BIOMEDICAL CIRCUITS AND SYSTEMS
(2022)
Article
Sport Sciences
Ruben Francisco, Filipe Jesus, Catarina L. Nunes, Andre Carvalho, Marta Alvim, Francesco Campa, Luis B. Sardinha, Goncalo V. Mendonca, Henry Lukaski, Analiza M. Silva
Summary: This study aimed to determine the predictive role of series and parallel bioelectrical impedance-derived parameters in predicting total body water, intracellular water, and extracellular water in athletes. The results showed that parallel bioelectrical impedance values can effectively predict fluid compartments in athletes, providing an alternative to the regularly used series measurements.
SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
(2023)
Article
Biotechnology & Applied Microbiology
Phasuwit P. Phatchayawat, Arnon Khamkeaw, Supansa Yodmuang, Muenduen Phisalaphong
Summary: Biopolymers of bacterial cellulose, chitosan, alginate and gelatin were combined to fabricate 3D hydrogel scaffolds for tissue engineering. The composite scaffolds exhibited good architecture and biocompatibility, making them suitable for cartilage tissue engineering applications.
BIOCHEMICAL ENGINEERING JOURNAL
(2022)
Article
Chemistry, Analytical
Xia Li, Fang Yang, Chunfang Gan, Ruo Yuan, Yun Xiang
Summary: This study develops a 3D DNA nanprobe for simultaneous monitoring of multiple miRNAs in live cells, showing enhanced reaction rate and stability compared to conventional probes.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Applied
Zhihui Li, Shikai Li, Jin Yang, Yujie Ha, Qianqian Zhang, Xiaojun Zhou, Chuanglong He
Summary: This study combines deferoxamine-loaded ethosomes with GelMA/GGMA hybrid bioink to create a 3D-printed scaffold using photo and ion-crosslinking. In vitro and in vivo experiments show that this composite scaffold promotes angiogenesis and bone regeneration, making it a promising candidate for bone defect treatment.
CARBOHYDRATE POLYMERS
(2022)
Article
Multidisciplinary Sciences
Asli Aybike Dogan, Martin Dufva
Summary: There is a high demand for complex cell cultures in various fields, with Transwell inserts being popular due to their commercial availability, ease of use, and versatility. Customizing inserts can offer potential benefits in terms of layers, height, and membrane composition, allowing for tailored experiments and improved culture formation.
SCIENTIFIC REPORTS
(2022)
Correction
Multidisciplinary Sciences
Asli Aybike Dogan, Martin Dufva
SCIENTIFIC REPORTS
(2022)
Correction
Multidisciplinary Sciences
Alessandro Fiorenzano, Edoardo Sozzi, Marcella Birtele, Janko Kajtez, Jessica Giacomoni, Fredrik Nilsson, Andreas Bruzelius, Yogita Sharma, Yu Zhang, Bengt Mattsson, Jenny Emneus, Daniella Rylander Ottosson, Petter Storm, Malin Parmar
NATURE COMMUNICATIONS
(2022)
Article
Chemistry, Multidisciplinary
Janko Kajtez, Milan Finn Wesseler, Marcella Birtele, Farinaz Riyahi Khorasgani, Daniella Rylander Ottosson, Arto Heiskanen, Tom Kamperman, Jeroen Leijten, Alberto Martinez-Serrano, Niels B. Larsen, Thomas E. Angelini, Malin Parmar, Johan U. Lind, Jenny Emneus
Summary: This article presents a modular platform for bioengineering of neuronal networks through direct embedded 3D printing of human stem cells inside Self-Healing Annealable Particle-Extracellular matrix (SHAPE) composites. The developed approach allows precise patterning of human stem cells and generation of mature subtype-specific neurons. Additionally, it enables multi-ink deposition, real-time monitoring of oxygen levels, and creation of vascular-like channels.
Article
Biochemistry & Molecular Biology
Shashank Vasudevan, Andrea Dotti, Janko Kajtez, Alberto Martinez-Serrano, Carsten Gundlach, Sandrina Campos Macas, Karin Lauschke, Anne-Marie Vinngaard, Silvia Garcia Lopez, Marta Pereira, Arto Heiskanen, Stephan S. Keller, Jenny Emneus
Summary: This study introduces a novel approach to generate Omni-LOEFs using laser ablation and demonstrates that dopamine detection current recorded from neurons differentiated on Omni-LOEFs upon light-induced stimulation is significantly higher compared to other materials.
BIOELECTROCHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Maria Niora, Mathilde Hauge Lerche, Martin Dufva, Kirstine Berg-Sorensen
Summary: Fluorescent nanodiamonds (FNDs) with negative nitrogen-vacancy (NV-) defect centers are ideal probes for biosensing applications and can potentially serve as biomarkers for cell differentiation. The uptake of FNDs by THP-1 monocytes and monocyte-derived M0-macrophages is studied, revealing differing FND-cell interactions and time-dependent uptake. FND uptake allows for distinction between cell subtypes based on phagocytic capacity, and FNDs demonstrate effective cell labeling and have potential for sensing biological processes involving cell differentiation.
Article
Biotechnology & Applied Microbiology
Asli Aybike Dogan, Martin Dufva
Summary: This study introduces a customized hanging insert for cultivating Caco-2 cells on hydrogel membranes under flow conditions. The device consists of an apical channel-like chamber for cell culture with shear force and a basolateral chamber that is mixed when rocked. The experiment investigates the impact of seeding density and flow on the growth of the cells. The results show that low seeding density and flow promote the formation of three-dimensional structures and improve barrier function.
BIOTECHNOLOGY AND BIOENGINEERING
(2023)
Article
Cardiac & Cardiovascular Systems
Didrik Lilja, Itai Schalit, Andreas Espinoza, Arnt Eltvedt Fiane, Gry Dahle, Helen Littorin-Sandbu, Fred -Johan Pettersen, Kristoffer E. Russell, Amrit P. S. Thiara, Ole Jakob Elle, Per Steinar Halvorsen
Summary: In a porcine model experiment, it was found that the changes in nonharmonic amplitudes (NHA) captured by the accelerometer can provide a reliable indication of subclinical gradual inflow obstructions, potentially supplementing PLVAD for earlier warnings and localization of pump.
JOURNAL OF HEART AND LUNG TRANSPLANTATION
(2023)
Article
Multidisciplinary Sciences
Martin Dufva
Summary: Out of 2828 screened articles, only 146 contained controls and quantified data for flow cell culture. Analysis of these articles showed that many biomarkers in all cell types were unaffected by flow, while only specific biomarkers responded strongly to flow.
SCIENTIFIC REPORTS
(2023)
Article
Multidisciplinary Sciences
Janko Kajtez, Carmen Radeke, Johan Ulrik Lind, Jenny Emneus
Summary: In the past decade, embedded 3D printing has emerged as a powerful tool for biofabrication of soft tissue constructs. However, the available granular gel support media have lacked the cell-adhesive and cell-instructive functions. To address this, a methodology for the generation of self-healing annealable particle-extracellular matrix (SHAPE) composites has been developed, which allows for both high-fidelity printing and adjustable biofunctional extracellular environment. This study demonstrates the precise biofabrication of human neural constructs using SHAPE composites.
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS
(2023)
Article
Chemistry, Analytical
Aaydha Chidambara Vinayaka, Van Ngoc Huynh, Than Linh Quyen, Trieu Nguyen, Mohsen Golabi, Mogens Madsen, Dang Duong Bang, Anders Wolff
Summary: Accurate and rapid detection of pathogens in animal-origin foods is crucial for the One Health Action Plan of the EU. We developed a LAMP-based point-of-care device called VETPOD for detecting Salmonella spp. The VETPOD uses a unique cartridge with pyramid-shaped optical structures for light detection, achieving comparable results to the ISO 6579-1 reference method with high sensitivity (96.51%) and specificity.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Trieu Nguyen, Aaydha Chidambara Vinayaka, Van Ngoc Huynh, Quyen Than Linh, Sune Zoega Andreasen, Mohsen Golabi, Dang Duong Bang, Jens Kjolseth Moller, Anders Wolff
Summary: This study presents a comprehensive work on the fabrication and clinical validation of a point of care (PoC) device for rapid and onsite detection of SARS-CoV-2. The device, named PATHPOD, can perform the detection of 10 different samples and two controls in less than 50 min, using a real-time reverse-transcription loop-mediated isothermal amplification (RT-LAMP) reaction on a polymer cartridge. The test has comparable sensitivity and specificity to the current golden standard RT-PCR.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Proceedings Paper
Engineering, Electrical & Electronic
Trieu Nguyen, Aaydha Chidambara Vinayaka, Van Ngoc Huynh, Quyen Than Linh, Sune Zoega Andreasen, Mohsen Golabi, Dang Duong Bang, Jens Kjolseth Moller, Anders Wolff
Summary: Sensitive and rapid on-site detection of SARS-CoV-2 using the PATHPOD device, which employs real-time reverse-transcription loop-mediated isothermal amplification (RT-rLAMP) reaction on a polymer cartridge, has been achieved. The PATHPOD PoC system, consisting of a standalone device and a cartridge, can identify 10 distinct samples and 2 controls in less than 50 minutes. This work presents the fabrication and clinical validation of the PATHPOD PoC system for the first time.
2023 IEEE 36TH INTERNATIONAL CONFERENCE ON MICRO ELECTRO MECHANICAL SYSTEMS, MEMS
(2023)
Article
Engineering, Biomedical
Salime Bazban-Shotorbani, Felicity Gavins, Krishna Kant, Martin Dufva, Nazila Kamaly
Summary: A dysfunctional endothelium is a hallmark of many diseases, including atherosclerosis. Researchers found that size plays a dominant role in nanoparticle targeting, with nanoparticles in the range of 30-60nm showing increased targeting to dysfunctional endothelium using a biomicrofluidic model. Additionally, treating dysfunctional endothelium with Annexin A1 resulted in restoration of adherens junctions and normalization of barrier integrity.
ADVANCED NANOBIOMED RESEARCH
(2022)
Article
Biophysics
Reza Khodadadi, Manouchehr Eghbal, Hamideh Ofoghi, Alireza Balaei, Ali Tamayol, Karen Abrinia, Amir Sanati-Nezhad, Mohamadmahdi Samandari
Summary: This paper introduces an integrated portable centrifugal microfluidic system that automates cell and fluid manipulation for complete blood counting (CBC) analysis at the point-of-care (POC). The system utilizes a specially designed microfluidic disc for cell separation, solution metering and mixing, and cell counting, and is equipped with a custom script for automated quantification of cells. The proposed method shows a strong correlation with the gold standard hematology analyzer for various blood parameters. The portable system offers simplicity, affordability, and low power consumption, making it a potential solution for improving healthcare delivery in resource-limited settings and remote areas.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Nabil H. Bhuiyan, Joon S. Shim
Summary: Developing herd immunity is crucial for changing the course of the COVID-19 pandemic. An AI-driven point-of-care testing platform has been proposed for analyzing the body's response to SARS-CoV-2, and it has been successfully used for quantifying viral proteins and antibodies in blood samples. A data-receptive web-based dashboard system has also been developed for real-time analysis of herd immunity progress.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Alexiane Godain, Timothy M. Vogel, Pascal Fongarland, Naoufel Haddour
Summary: This study provides comprehensive insights into the intricate relationship between shear stress and electroactive biofilms in microbial fuel cells, highlighting the pivotal role of shear stress in influencing the growth kinetics, electrical performance, and physical structure of the biofilms. The study also emphasizes the complexities of extracellular electron transfer mechanisms and the need for complementary metaproteomic analyses.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Linjie Wang, Yixin Chen, Yang Ji, Shujun Zheng, Fei Wang, Caolong Li
Summary: A paper-based biosensor incorporating surface-enhanced Raman spectroscopy (SERS) and colorimetric detection has been developed for efficient quantification of intracellular glutathione (GSH). The biosensor exhibits excellent selectivity, stability, and precision, with low detection limits in both SERS and colorimetric modes. It has been successfully utilized for intracellular GSH detection and validated against a commercial GSH assay kit.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Quan Zhou, Jing Wang, Zhen Zhang, Alain Wuethrich, Richard J. Lobb, Matt Trau
Summary: This study presents a biosensor for sensitive detection of EMT-associated biomarkers on extracellular vesicles (EVs) surfaces during targeted therapy. Through longitudinal monitoring of patients, the biosensor shows its ability to identify the EMT-like phenotype switching on circulating EVs during the development of resistance.
BIOSENSORS & BIOELECTRONICS
(2024)
Review
Biophysics
Pratika Rai, Sabrina N. Hoba, Celine Buchmann, Robert J. Subirana-Slotos, Christian Kersten, Tanja Schirmeister, Kristina Endres, Bernd Bufe, Alexey Tarasov
Summary: Proteases have been proposed as potential biomarkers for various pathological conditions. The development of protease biosensors offers a more efficient way to investigate dysregulated proteases. This review article presents different optical and electrochemical detection methods for designing biosensors for all major protease families.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Chengxin Liu, Xu Shen, Li Yan, Runlian Qu, Yue Wang, Yaqin He, Zixuan Zhan, Piaopiao Chen, Feng Lin
Summary: In this study, a homogeneous rapid electrochemical aptasensor was developed to quantitatively detect CTCs in lung cancer patients. The aptasensor utilized a DNA nanosphere structure and a complementary aptamer to specifically detect mucin 1 as a marker for CTCs. The assay exhibited high specificity and sensitivity, and the results were consistent with other detection methods.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Danni Xue, Xing Dai, Jialong Zhao, Jiayao Zhang, Huan Liu, Kui Liu, Tao Xu, Chenjie Gu, Xingfei Zhou, Tao Jiang
Summary: In this study, a dual-enhancement SERS substrate based on Ti3C2TX and Ag nanocubes was fabricated for precise quantification of ritonavir and ibrutinib in serum. The formation of numerous electromagnetic hotspots between Ag nanocubes facilitated effective photo-induced charge transfer. The composite substrate showed excellent sensitivity, achieving low detection limits and high recoveries, making it promising for monitoring and identification of clinical blood drug concentration.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Tenghua Zhang, Zihui Xie, Xiaohe Zheng, Yuxin Liang, Yao Lu, Hankang Zhong, Feiyang Qian, Yuqing Zhu, Ruiting Sun, Yan Sheng, Jiaming Hu
Summary: This study reports a technology based on cationic lipid-polymer hybrid nanoparticles for efficient extracellular vesicle (EV) enrichment and in-situ detection of internal microRNAs. The technology demonstrates high EV enrichment efficiency and sensitive internal RNA detection, making it potentially useful for early pancreatic cancer diagnosis.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Wenjie Dai, Gaoxu Chen, Xiaoyan Wang, Shujun Zhen, Chengzhi Huang, Lei Zhan, Yuanfang Li
Summary: In this study, a novel metal organic gel (MOG) with dual electrochemiluminescence (ECL) properties was prepared by simple mixing. The MOG exhibited strong and stable anodic and cathodic ECL signals. By utilizing this MOG, an ECL resonance energy transfer (ECL-RET) biosensor was constructed for ultrasensitive detection of a specific gene. The study developed a straightforward technique for obtaining a single luminescent material with dual signals and expanded the analytical application of MOGs in the realm of ECL.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Lais Canniatti Brazaca, Amanda Hikari Imamura, Rodrigo Vieira Blasques, Jessica Rocha Camargo, Bruno Campos Janegitz, Emanuel Carrilho
Summary: The use of microfluidic paper-based analytical devices (muPADs) for medical diagnosis is a growing trend due to their low cost, easy use, simple manufacturing, and potential for application in low-resource settings. This review focuses on the advances in muPADs for medical diagnostics, discussing their use in detecting various biomarkers in common human biofluids. The challenges of biomarker detection in each sample are examined, along with innovative techniques to overcome these limitations. The commercialization difficulties of muPADs are also considered, along with future trends such as wearable devices and integrated platforms.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Minghong Jian, Xudong Sun, Hua Zhang, Xiaotong Li, Shasha Li, Zhenxin Wang
Summary: Matrix metalloproteinases (MMPs) are attractive biomarkers for cancer diagnosis and treatment, but their low abundance in biological samples, especially in the early stages of tumors, makes it challenging to precisely analyze MMP activities. In this study, a peptide microarray-based metal-enhanced fluorescence assay (PMMEFA) is proposed as a sensitive and specific method to simultaneously detect MMP-1, -2, -3, -7, -9, and -13 activities. The PMMEFA showed excellent sensitivity and was capable of detecting MMP activities in various matrices.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Kyung Ho Kim, Eunsu Ryu, Zinah Hilal Khaleel, Sung Eun Seo, Lina Kim, Yong Ho Kim, Hyun Gyu Park, Oh Seok Kwon
Summary: We have developed a novel strategy for discriminative detection of SARS-CoV-2 variants using the plasmonic photothermal effect of gold nanofilms and digital polymerase chain reaction (dPCR) technology. With this method, we were able to detect the delta and omicron variants with high sensitivity within 25 minutes from COVID-19 patients' clinical samples, making it a rapid and accurate point-of-care testing tool.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Zepeng Kang, Yuanming Wang, Haiyan Song, Xueli Wang, Job Zhang, Zhiguang Zhu
Summary: By designing a wearable and flexible lactic-acid/O2 EBFC with an air-breathing biocathode, the limitations of biocathode are effectively solved. The optimal performance conditions are determined through experiments, and the EBFC is successfully applied to power a low-power device.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Huayun Chen, Zhiheng You, Yuhui Hong, Xiao Wang, Mingming Zhao, Yushi Luan, Yibin Ying, Yixian Wang
Summary: This study developed a colorimetric sensor array using gas-responsive two-dimensional metal-organic framework (MOF) composites for highly sensitive detection of volatile organic compounds (VOCs). The dye/Zn-2(bim)(4) composites-based sensor arrays showed enhanced sensitivity and anti-interference properties. The findings demonstrate the potential use of dye/Zn-2(bim)(4) sensor arrays for early perception of plant diseases.
BIOSENSORS & BIOELECTRONICS
(2024)