TRIM21 is a novel regulator of Par-4 in colon and pancreatic cancer cells

Platinum-based drugs: past, present and future

(2016) Shahana Dilruba et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Inhibition of AKT promotes FOXO3a-dependent apoptosis in prostate cancer

(2016) T P Das et al.   Cell Death & Disease

Post-translational regulation of the cleaved fragment of Par-4 in ovarian and endometrial cancer cells

(2016) Kevin Brasseur et al.   Oncotarget

Novel therapeutic agents in the treatment of metastatic colorectal cancer

(2016) Sachin Gopalkrishna Pai   World Journal of Gastrointestinal Oncology

Is metastatic pancreatic cancer an untargetable malignancy?

(2016) Hampig Raphael Kourie et al.   World Journal of Gastrointestinal Oncology

Degradation of Stop Codon Read-through Mutant Proteins via the Ubiquitin-Proteasome System Causes Hereditary Disorders

(2015) Norihito Shibata et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reduced expression of TRIM21/Ro52 predicts poor prognosis in diffuse large B-cell lymphoma patients with and without rheumatic disease

(2015) S. Brauner et al.   JOURNAL OF INTERNAL MEDICINE

Downregulation of TRIM21 contributes to hepatocellular carcinoma carcinogenesis and indicates poor prognosis of cancers

(2015) Qianshan Ding et al.   TUMOR BIOLOGY

Fbxo45-mediated degradation of the tumor-suppressor Par-4 regulates cancer cell survival

(2014) X Chen et al.   CELL DEATH AND DIFFERENTIATION

The E3 Ubiquitin Ligase Ro52 Negatively Regulates IFN-  Production Post-Pathogen Recognition by Polyubiquitin-Mediated Degradation of IRF3

(2014) R. Higgs et al.   JOURNAL OF IMMUNOLOGY

TRIpartite Motif 21 (TRIM21) Differentially Regulates the Stability of Interferon Regulatory Factor 5 (IRF5) Isoforms

(2014) Elisa Lazzari et al.   PLoS One

ROS-dependent prostate apoptosis response-4 (Par-4) up-regulation and ceramide generation are the prime signaling events associated with curcumin-induced autophagic cell death in human malignant glioma

(2014) Faisal Thayyullathil et al.   FEBS Open Bio

Par-4 downregulation confers cisplatin resistance in pancreatic cancer cells via PI3K/Akt pathway-dependent EMT

(2013) Jiaxin Tan et al.   TOXICOLOGY LETTERS

Par-4 as a potential target for cancer therapy

(2012) Rosalyn B Irby et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

The immunobiology of Ro52 (TRIM21) in autoimmunity: A critical review

(2012) Vilija Oke et al.   JOURNAL OF AUTOIMMUNITY

The E3 ubiquitin ligase TRIM21 negatively regulates the innate immune response to intracellular double-stranded DNA

(2012) Zhiqiang Zhang et al.   NATURE IMMUNOLOGY

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

SS-A/Ro52 promotes apoptosis by regulating Bcl-2 production

(2011) Siti Nur Aisyah Jauharoh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Akt Inhibitor ISC-4 Activates Prostate Apoptosis Response Protein-4 and Reduces Colon Tumor Growth in a Nude Mouse Model

(2011) A. K. Sharma et al.   CLINICAL CANCER RESEARCH

Prostate Apoptosis Response 4 (Par-4), a Novel Substrate of Caspase-3 during Apoptosis Activation

(2011) P. Chaudhry et al.   MOLECULAR AND CELLULAR BIOLOGY

Delivery of PAR-4 plasmid in vivo via nanoliposomes sensitizes colon tumor cells subcutaneously implanted into nude mice to 5-FU

(2010) Christina Leah Kline et al.   CANCER BIOLOGY & THERAPY

Overexpression of Par-4 sensitizes TRAIL-induced apoptosis via inactivation of NF-κB and Akt signaling pathways in renal cancer cells

(2010) Tae-Jin Lee et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Par-4 inhibits Akt and suppresses Ras-induced lung tumorigenesis

(2008) Jayashree Joshi et al.   EMBO JOURNAL

Critical role of prostate apoptosis response-4 in determining the sensitivity of pancreatic cancer cells to small-molecule inhibitor-induced apoptosis

(2008) A. S. Azmi et al.   MOLECULAR CANCER THERAPEUTICS

Chemoprevention of Pancreatic Cancer: Characterization of Par-4 and its Modulation by 3,3′ Diindolylmethane (DIM)

(2008) Asfar Sohail Azmi et al.   PHARMACEUTICAL RESEARCH

Overexpression of Par-4 enhances thapsigargin-induced apoptosis via down-regulation of XIAP and inactivation of Akt in human renal cancer cells

(2007) Tae-Jin Lee et al.   JOURNAL OF CELLULAR BIOCHEMISTRY