Blood natural killer cell deficiency reveals an immunotherapy strategy for atopic dermatitis

Chronic Pruritus of Unknown Origin (CPUO): Uniform Nomenclature and Diagnosis as a Pathway to Standardized Understanding and Treatment

(2019) Brian S. Kim et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

NK cells are activated and primed for skin-homing during acute dengue virus infection in humans

(2019) Christine L. Zimmer et al.   Nature Communications

First-in-human phase 1 clinical study of the IL-15 superagonist complex ALT-803 to treat relapse after transplantation

(2018) Rizwan Romee et al.   BLOOD

British Association of Dermatologists’ guidelines for the investigation and management of generalized pruritus in adults without an underlying dermatosis, 2018

(2018) G.W.M. Millington et al.   BRITISH JOURNAL OF DERMATOLOGY

Diversification of human NK cells: Lessons from deep profiling

(2018) Aaron J. Wilk et al.   JOURNAL OF LEUKOCYTE BIOLOGY

ALT-803, an IL-15 superagonist, in combination with nivolumab in patients with metastatic non-small cell lung cancer: a non-randomised, open-label, phase 1b trial

(2018) John M Wrangle et al.   LANCET ONCOLOGY

CD56 Expression Marks Human Group 2 Innate Lymphoid Cell Divergence from a Shared NK Cell and Group 3 Innate Lymphoid Cell Developmental Pathway

(2018) Luxi Chen et al.   IMMUNITY

Anti-NKG2A mAb Is a Checkpoint Inhibitor that Promotes Anti-tumor Immunity by Unleashing Both T and NK Cells

(2018) Pascale André et al.   CELL

Gene Regulatory Programs Conferring Phenotypic Identities to Human NK Cells

(2018) Patrick L. Collins et al.   CELL

Combination therapy with IL-15 superagonist (ALT-803) and PD-1 blockade enhances human NK cell immunotherapy against ovarian cancer

(2017) M.A. Geller et al.   GYNECOLOGIC ONCOLOGY

CD56bright NK cells exhibit potent antitumor responses following IL-15 priming

(2017) Julia A. Wagner, Maximillian Rosario, Rizwan Romee, Melissa M. Berrien-Elliott, Stephanie E. Schneider, Jeffrey W. Leong, Ryan P. Sullivan, Brea A. Jewell, Michelle Becker-Hapak, Timothy Schappe, Sara Abdel-Latif, Aaron R. Ireland, Devika Jaishankar, Justin A. King, Ravi Vij, Dennis Clement, Jodie Goodridge, Karl-Johan Malmberg, Hing C. Wong, Todd A. Fehniger   JOURNAL OF CLINICAL INVESTIGATION

NK Cells Alleviate Lung Inflammation by Negatively Regulating Group 2 Innate Lymphoid Cells

(2017) Jiacheng Bi et al.   JOURNAL OF IMMUNOLOGY

Increased Risk of Cutaneous and Systemic Infections in Atopic Dermatitis—A Cohort Study

(2017) Sinéad M. Langan et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The Burden of Atopic Dermatitis: Summary of a Report for the National Eczema Association

(2017) Aaron M. Drucker et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Global Skin Disease Morbidity and Mortality

(2017) Chante Karimkhani et al.   JAMA Dermatology

Relationship ofNKG2CCopy Number with the Distribution of Distinct Cytomegalovirus-Induced Adaptive NK Cell Subsets

(2016) Aura Muntasell et al.   JOURNAL OF IMMUNOLOGY

Retrospective analysis of data from an itch center: Integrating validated tools in the electronic health record

(2016) Nicholas K. Mollanazar et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Immune dysregulation underlies a subset of patients with chronic idiopathic pruritus

(2016) Amy Z. Xu et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Efficacy and safety of dupilumab in adults with moderate-to-severe atopic dermatitis inadequately controlled by topical treatments: a randomised, placebo-controlled, dose-ranging phase 2b trial

(2016) Diamant Thaçi et al.   LANCET

Inflammatory triggers associated with exacerbations of COPD orchestrate plasticity of group 2 innate lymphoid cells in the lungs

(2016) Jonathan S Silver et al.   NATURE IMMUNOLOGY

Two Phase 3 Trials of Dupilumab versus Placebo in Atopic Dermatitis

(2016) Eric L. Simpson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cytokine-induced memory-like natural killer cells exhibit enhanced responses against myeloid leukemia

(2016) Rizwan Romee et al.   Science Translational Medicine

Imputation of KIR Types from SNP Variation Data

(2015) Damjan Vukcevic et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Game, set, match for factor VIII mismatch?

(2015) C. H. Miller   BLOOD

Cytomegalovirus Infection Drives Adaptive Epigenetic Diversification of NK Cells with Altered Signaling and Effector Function

(2015) Heinrich Schlums et al.   IMMUNITY

Interleukin-33 and Interferon-γ Counter-Regulate Group 2 Innate Lymphoid Cell Activation during Immune Perturbation

(2015) Ari B. Molofsky et al.   IMMUNITY

IL-15 Superagonist–Mediated Immunotoxicity: Role of NK Cells and IFN-γ

(2015) Yin Guo et al.   JOURNAL OF IMMUNOLOGY

Interferon and IL-27 antagonize the function of group 2 innate lymphoid cells and type 2 innate immune responses

(2015) Kazuyo Moro et al.   NATURE IMMUNOLOGY

Robust enumeration of cell subsets from tissue expression profiles

(2015) Aaron M Newman et al.   NATURE METHODS

Palladium-based mass tag cell barcoding with a doublet-filtering scheme and single-cell deconvolution algorithm

(2015) Eli R Zunder et al.   Nature Protocols

Human NK cell repertoire diversity reflects immune experience and correlates with viral susceptibility

(2015) Dara M. Strauss-Albee et al.   Science Translational Medicine

Basophils Promote Innate Lymphoid Cell Responses in Inflamed Skin

(2014) Brian S. Kim et al.   JOURNAL OF IMMUNOLOGY

Guidelines of care for the management of atopic dermatitis

(2014) Robert Sidbury et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Dupilumab Treatment in Adults with Moderate-to-Severe Atopic Dermatitis

(2014) Lisa A. Beck et al.   NEW ENGLAND JOURNAL OF MEDICINE

Tissue-resident natural killer (NK) cells are cell lineages distinct from thymic and conventional splenic NK cells

(2014) Dorothy K Sojka et al.   eLife

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

NK cell CD16 surface expression and function is regulated by a disintegrin and metalloprotease-17 (ADAM17)

(2013) R. Romee et al.   BLOOD

Normalization of mass cytometry data with bead standards

(2013) Rachel Finck et al.   CYTOMETRY PART A

Adaptive reconfiguration of the human NK-cell compartment in response to cytomegalovirus: A different perspective of the host-pathogen interaction

(2013) Aura Muntasell et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Protective effect of the KIR2DS1 gene in atopic dermatitis

(2013) Wanda Niepiekło-Miniewska et al.   GENE

Basophils and allergic inflammation

(2013) Mark C. Siracusa et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A role for IL-25 and IL-33–driven type-2 innate lymphoid cells in atopic dermatitis

(2013) Maryam Salimi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions

(2013) Roderick J. Hay et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Cutaneous immunosurveillance and regulation of inflammation by group 2 innate lymphoid cells

(2013) Ben Roediger et al.   NATURE IMMUNOLOGY

TSLP Elicits IL-33-Independent Innate Lymphoid Cell Responses to Promote Skin Inflammation

(2013) B. S. Kim et al.   Science Translational Medicine

Functional Significance of CD57 Expression on Human NK Cells and Relevance to Disease

(2013) Carolyn M. Nielsen et al.   Frontiers in Immunology

RSeQC: quality control of RNA-seq experiments

(2012) Liguo Wang et al.   BIOINFORMATICS

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Peripheral natural killer cells exhibit qualitative and quantitative changes in patients with psoriasis and atopic dermatitis

(2012) C. Luci et al.   BRITISH JOURNAL OF DERMATOLOGY

Identification of human NK cells that are deficient for signaling adaptor FcR  and specialized for antibody-dependent immune functions

(2012) I. Hwang et al.   INTERNATIONAL IMMUNOLOGY

IgE, Mast Cells, and Eosinophils in Atopic Dermatitis

(2011) Fu-Tong Liu et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Fate mapping analysis of lymphoid cells expressing the NKp46 cell surface receptor

(2011) E. Narni-Mancinelli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression patterns of NKG2A, KIR, and CD57 define a process of CD56dim NK-cell differentiation uncoupled from NK-cell education

(2010) N. K. Bjorkstrom et al.   BLOOD

PRDM1/Blimp-1 Controls Effector Cytokine Production in Human NK Cells

(2010) M. A. Smith et al.   JOURNAL OF IMMUNOLOGY

CD56 negative NK cells: origin, function, and role in chronic viral disease

(2010) Niklas K. Björkström et al.   TRENDS IN IMMUNOLOGY

GAGE: generally applicable gene set enrichment for pathway analysis

(2009) Weijun Luo et al.   BMC BIOINFORMATICS

Expansion of CD56− NK cells in chronic HCV/HIV-1 co-infection: Reversion by antiviral treatment with pegylated IFNα and ribavirin

(2008) Veronica D. Gonzalez et al.   CLINICAL IMMUNOLOGY