Triptolide mitigates radiation-induced pulmonary fibrosis via inhibition of axis of alveolar macrophages-NOXes-ROS-myofibroblasts

p47phox contributes to albuminuria and kidney fibrosis in mice

(2015) Hongtao Wang et al.   KIDNEY INTERNATIONAL

Deficiency of NOX1 or NOX4 Prevents Liver Inflammation and Fibrosis in Mice through Inhibition of Hepatic Stellate Cell Activation

(2015) Tian Lan et al.   PLoS One

Inorganic Arsenic Activates Reduced NADPH Oxidase in Human Primary Macrophages through a Rho Kinase/p38 Kinase Pathway

(2014) Anthony Lemarie et al.   JOURNAL OF IMMUNOLOGY

Anti-inflammatory effects of triptolide by inhibiting the NF-κB signalling pathway in LPS-induced acute lung injury in a murine model

(2014) XIAN WANG et al.   Molecular Medicine Reports

Reversal of Persistent Fibrosis in Aging by Targeting Nox4-Nrf2 Redox Imbalance

(2014) L. Hecker et al.   Science Translational Medicine

Targeting NOX enzymes in pulmonary fibrosis

(2012) Louise Hecker et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Ethanol Induces Oxidative Stress in Alveolar Macrophages via Upregulation of NADPH Oxidases

(2012) S. M. Yeligar et al.   JOURNAL OF IMMUNOLOGY

Development and Licensure of Medical Countermeasures to Treat Lung Damage Resulting from a Radiological or Nuclear Incident

(2012) Andrea L. DiCarlo et al.   RADIATION RESEARCH

Ly6ChiMonocytes Direct Alternatively Activated Profibrotic Macrophage Regulation of Lung Fibrosis

(2011) Michael A. Gibbons et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A Key Role for NOX4 in Epithelial Cell Death During Development of Lung Fibrosis

(2011) Stephanie Carnesecchi et al.   ANTIOXIDANTS & REDOX SIGNALING

Inflammation and wound healing: the role of the macrophage

(2011) Timothy J. Koh et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Triptolide Mitigates Radiation-induced Pulmonary Fibrosis and Its Action Mechanism

(2011) S. Yang et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Myofibroblast differentiation during fibrosis: role of NAD(P)H oxidases

(2011) Jeffrey L. Barnes et al.   KIDNEY INTERNATIONAL

Antifibrotic Effects of Triptolide on Hepatic Stellate Cells and Dimethylnitrosamine-intoxicated Rats

(2011) Lee-Won Chong et al.   PHYTOTHERAPY RESEARCH

Triptolide attenuates renal interstitial fibrosis in rats with unilateral ureteral obstruction

(2010) XIAO-PENG YUAN et al.   NEPHROLOGY

Reactive Oxygen Species Are Required for Maintenance and Differentiation of Primary Lung Fibroblasts in Idiopathic Pulmonary Fibrosis

(2010) Marialuisa Bocchino et al.   PLoS One

Pathogenetic mechanisms in radiation fibrosis

(2010) John Yarnold et al.   RADIOTHERAPY AND ONCOLOGY

NOX Enzymes and Pulmonary Disease

(2009) Brian Griffith et al.   ANTIOXIDANTS & REDOX SIGNALING

NAD(P)H Oxidase Mediates TGF- 1-Induced Activation of Kidney Myofibroblasts

(2009) C. D. Bondi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury

(2009) Louise Hecker et al.   NATURE MEDICINE

Homocysteine enhances cell proliferation in hepatic myofibroblastic stellate cells

(2008) Cheng-Gang Zou et al.   JOURNAL OF MOLECULAR MEDICINE-JMM