Biliary cancer: Utility of next-generation sequencing for clinical management

Surgery for Recurrent Biliary Tract Cancer

(2015) Yu Takahashi et al.   ANNALS OF SURGERY

Comprehensive genomic profiling of extrahepatic cholangiocarcinoma reveals a long tail of therapeutic targets

(2015) Hwajeong Lee et al.   JOURNAL OF CLINICAL PATHOLOGY

HER2/neu-directed therapy for biliary tract cancer

(2015) Milind Javle et al.   Journal of Hematology & Oncology

Abstract PL04-05: The first reported results of AG-120, a first-in-class, potent inhibitor of the IDH1 mutant protein, in a Phase I study of patients with advanced IDH1-mutant solid tumors, including gliomas

(2015) Howard Burris et al.   MOLECULAR CANCER THERAPEUTICS

Prognosis and Clinicopathologic Features of Patients With Advanced Stage Isocitrate Dehydrogenase (IDH) Mutant and IDH Wild-Type Intrahepatic Cholangiocarcinoma

(2015) L. Goyal et al.   ONCOLOGIST

Outcomes in biliary malignancy

(2014) Bas Groot Koerkamp et al.   JOURNAL OF SURGICAL ONCOLOGY

Cholangiocarcinoma

(2014) Nataliya Razumilava et al.   LANCET

New Routes to Targeted Therapy of Intrahepatic Cholangiocarcinomas Revealed by Next-Generation Sequencing

(2014) J. S. Ross et al.   ONCOLOGIST

Mutation Profiling in Cholangiocarcinoma: Prognostic and Therapeutic Implications

(2014) Chaitanya R. Churi et al.   PLoS One

Distal Cholangiocarcinoma

(2014) Paxton V. Dickson et al.   SURGICAL CLINICS OF NORTH AMERICA

Proximal Biliary Tumors

(2014) Kimberly M. Brown et al.   SURGICAL CLINICS OF NORTH AMERICA

Gallbladder Cancer

(2014) Jessica A. Wernberg et al.   SURGICAL CLINICS OF NORTH AMERICA

Mutational landscape of intrahepatic cholangiocarcinoma

(2014) Shanshan Zou et al.   Nature Communications

Integrated Genomic Characterization Reveals Novel, Therapeutically Relevant Drug Targets in FGFR and EGFR Pathways in Sporadic Intrahepatic Cholangiocarcinoma

(2014) Mitesh J. Borad et al.   PLoS Genetics

Molecular Diagnostics in the Neoplasms of the Pancreas, Liver, Gall Bladder, and Extrahepatic Biliary Tract

(2013) Michael Weindel et al.   CLINICS IN LABORATORY MEDICINE

Pathogenesis, Diagnosis, and Management of Cholangiocarcinoma

(2013) Sumera Rizvi et al.   GASTROENTEROLOGY

Integrative Molecular Analysis of Intrahepatic Cholangiocarcinoma Reveals 2 Classes That Have Different Outcomes

(2013) Daniela Sia et al.   GASTROENTEROLOGY

Fibroblast growth factor receptor 2 tyrosine kinase fusions define a unique molecular subtype of cholangiocarcinoma

(2013) Yasuhito Arai et al.   HEPATOLOGY

Molecular profiling of cholangiocarcinoma shows potential for targeted therapy treatment decisions

(2013) Jesse S. Voss et al.   HUMAN PATHOLOGY

The frequency of KRAS and BRAF mutations in intrahepatic cholangiocarcinomas and their correlation with clinical outcome

(2013) Scott Robertson et al.   HUMAN PATHOLOGY

Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing

(2013) Garrett M Frampton et al.   NATURE BIOTECHNOLOGY

Epidemiology and Risk Factors of Biliary Tract and Primary Liver Tumors

(2013) Mathew M. Augustine et al.   Surgical Oncology Clinics of North America

Identification of Targetable FGFR Gene Fusions in Diverse Cancers

(2013) Yi-Mi Wu et al.   Cancer Discovery

Classification, Diagnosis, and Management of Cholangiocarcinoma

(2012) Nataliya Razumilava et al.   Clinical Gastroenterology and Hepatology

Biliary tract carcinomas: From chemotherapy to targeted therapy

(2012) Donatella Marino et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Genetic profiling of intrahepatic cholangiocarcinoma

(2012) Jesper B. Andersen et al.   CURRENT OPINION IN GASTROENTEROLOGY

Isocitrate dehydrogenase 1 and 2 mutations in cholangiocarcinoma

(2012) Benjamin R. Kipp et al.   HUMAN PATHOLOGY

Adjuvant Therapy in the Treatment of Biliary Tract Cancer: A Systematic Review and Meta-Analysis

(2012) Anne M. Horgan et al.   JOURNAL OF CLINICAL ONCOLOGY

Targeted therapy for biliary tract cancers

(2012) Jason E. Faris et al.   Journal of Hepato-Biliary-Pancreatic Sciences

Functional analysis of receptor tyrosine kinase mutations in lung cancer identifies oncogenic extracellular domain mutations of ERBB2

(2012) H. Greulich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomic and Genetic Characterization of Cholangiocarcinoma Identifies Therapeutic Targets for Tyrosine Kinase Inhibitors

(2011) Jesper B. Andersen et al.   GASTROENTEROLOGY

How to apply de Bruijn graphs to genome assembly

(2011) Phillip E C Compeau et al.   NATURE BIOTECHNOLOGY

Clinical diagnosis and staging of cholangiocarcinoma

(2011) Boris Blechacz et al.   Nature Reviews Gastroenterology & Hepatology

Genetics of Biliary Tract Cancers and Emerging Targeted Therapies

(2010) Aram F. Hezel et al.   JOURNAL OF CLINICAL ONCOLOGY

Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations

(2010) Stefan Gross et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Isocitrate Dehydrogenase 1 and 2 Mutations in Cancer: Alterations at a Crossroads of Cellular Metabolism

(2010) Z. J. Reitman et al.   JNCI-Journal of the National Cancer Institute

COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

(2010) S. A. Forbes et al.   NUCLEIC ACIDS RESEARCH

EGFR and HER2 expression in advanced biliary tract cancer

(2009) Jan Harder et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Systemic Therapy for Biliary Tract Cancers

(2008) A. F. Hezel et al.   ONCOLOGIST