Metformin enhances the immunomodulatory potential of adipose-derived mesenchymal stem cells through STAT1 in an animal model of lupus

Metformin and Autoimmunity: A “New Deal” of an Old Drug

(2018) Francesco Ursini et al.   Frontiers in Immunology

IFN-γ orchestrates mesenchymal stem cell plasticity through the signal transducer and activator of transcription 1 and 3 and mammalian target of rapamycin pathways

(2017) Tiziana Vigo et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Therapeutic Potential of Targeting the Th17/Treg Axis in Autoimmune Disorders

(2017) Patrizia Fasching et al.   MOLECULES

Pathways leading to an immunological disease: systemic lupus erythematosus

(2017) Olga Zharkova et al.   RHEUMATOLOGY

Assessing Autophagy in Mouse Models and Patients with Systemic Autoimmune Diseases

(2017) Fengjuan Wang et al.   Cells

Inhibition of SHP2 ameliorates the pathogenesis of systemic lupus erythematosus

(2016) Jianxun Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Overexpression of soluble RAGE in mesenchymal stem cells enhances their immunoregulatory potential for cellular therapy in autoimmune arthritis

(2016) Min-Jung Park et al.   Scientific Reports

PI3kα and STAT1 Interplay Regulates Human Mesenchymal Stem Cell Immune Polarization

(2015) Marwan Mounayar et al.   STEM CELLS

Function of the Th17/Interleukin-17A Immune Response in Murine Lupus Nephritis

(2015) Tilman Schmidt et al.   Arthritis & Rheumatology

Th17 and regulatory T cell balance in autoimmune and inflammatory diseases

(2014) Mélissa Noack et al.   AUTOIMMUNITY REVIEWS

Metformin: From Mechanisms of Action to Therapies

(2014) Marc Foretz et al.   Cell Metabolism

Double Negative (DN) αβ T Cells: misperception and overdue recognition

(2014) Maria N Martina et al.   IMMUNOLOGY AND CELL BIOLOGY

Expanded Double Negative T Cells in Patients with Systemic Lupus Erythematosus Produce IL-17 and Infiltrate the Kidneys

(2014) J. C. Crispin et al.   JOURNAL OF IMMUNOLOGY

Mesenchymal Stem Cells Induce an Inflammatory Response After Intravenous Infusion

(2013) Martin J. Hoogduijn et al.   STEM CELLS AND DEVELOPMENT

Adipose Tissue-Derived Multipotent Stromal Cells Have a Higher Immunomodulatory Capacity Than Their Bone Marrow-Derived Counterparts

(2013) Sara M. Melief et al.   Stem Cells Translational Medicine

Mesenchymal stem cells are conditionally therapeutic in preclinical models of rheumatoid arthritis

(2012) Anastasia Papadopoulou et al.   ANNALS OF THE RHEUMATIC DISEASES

Mesenchymal Stem Cell treatment for autoimmune diseases: a critical review

(2012) Fernando E Figueroa et al.   BIOLOGICAL RESEARCH

Interleukin-17 Cytokines Are Critical in Development of Fatal Lupus Glomerulonephritis

(2012) Prapaporn Pisitkun et al.   IMMUNITY

Absence of CD59 Exacerbates Systemic Autoimmunity in MRL/lpr Mice

(2012) T. Miwa et al.   JOURNAL OF IMMUNOLOGY

Therapeutic metformin/AMPK activation blocked lymphoma cell growth via inhibition of mTOR pathway and induction of autophagy

(2012) W-Y Shi et al.   Cell Death & Disease

Toll-Like Receptors as Modulators of Mesenchymal Stem Cells

(2012) Olga DelaRosa et al.   Frontiers in Immunology

AMPK and mTOR in Cellular Energy Homeostasis and Drug Targets

(2011) Ken Inoki et al.   Annual Review of Pharmacology and Toxicology

Disturbed Th1, Th2, Th17 and Treg balance in patients with systemic lupus erythematosus

(2011) Sebastian Dolff et al.   CLINICAL IMMUNOLOGY

Murine Models of Systemic Lupus Erythematosus

(2011) Daniel Perry et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Systemic Lupus Erythematosus

(2011) George C. Tsokos   NEW ENGLAND JOURNAL OF MEDICINE

Elevated Th17 cells are accompanied by FoxP3+ Treg cells decrease in patients with lupus nephritis

(2011) Qian Xing et al.   RHEUMATOLOGY INTERNATIONAL

Pretreatment with Interferon-γ Enhances the Therapeutic Activity of Mesenchymal Stromal Cells in Animal Models of Colitis

(2011) Marjolijn Duijvestein et al.   STEM CELLS

Dysregulated balance of Th17 and Th1 cells in systemic lupus erythematosus

(2010) Kamini Shah et al.   ARTHRITIS RESEARCH & THERAPY

Cross-regulation of Signaling Pathways by Interferon-γ: Implications for Immune Responses and Autoimmune Diseases

(2009) Xiaoyu Hu et al.   IMMUNITY

Inactivation of Mammalian Target of Rapamycin Increases STAT1 Nuclear Content and Transcriptional Activity in α4- and Protein Phosphatase 2A-dependent Fashion

(2009) Jill A. Fielhaber et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Requirement of IFN-γ–Mediated Indoleamine 2,3-Dioxygenase Expression in the Modulation of Lymphocyte Proliferation by Human Adipose–Derived Stem Cells

(2009) Olga DelaRosa et al.   TISSUE ENGINEERING PART A

TGF-β and Regulatory T Cell in Immunity and Autoimmunity

(2008) Yisong Y. Wan et al.   JOURNAL OF CLINICAL IMMUNOLOGY

A critical function for TGF-β signaling in the development of natural CD4+CD25+Foxp3+ regulatory T cells

(2008) Yongzhong Liu et al.   NATURE IMMUNOLOGY