Article
Critical Care Medicine
Boon Kiat Kenneth Tan, Yun Xin Chin, Zhi Xiong Koh, Nur Ain Zafirah Bte Md Said, Masnita Rahmat, Stephanie Fook-Chong, Yih Yng Ng, Marcus Eng Hock Ong
Summary: This study investigated the use of intraosseous access in out-of-hospital cardiac arrest patients, showing that using IO resulted in higher vascular access success rates and faster adrenaline administration, but did not significantly impact ROSC, survival to discharge, or good neurological outcomes.
Article
Critical Care Medicine
Tatsuma Fukuda, Naoko Ohashi-Fukuda, Ryota Inokuchi, Yutaka Kondo, Takayuki Taira, Ichiro Kukita
Summary: This study analyzed nationwide registry data in Japan and found that delayed epinephrine administration was associated with lower 1-month neurologically favorable survival among out-of-hospital cardiac arrest patients.
Article
Emergency Medicine
Shang-Chiao Yang, Yu-Hao Hsu, Yung -Hsiang Chang, Liang-Tien Chien, I. -Chung Chen, Wen-Chu Chiang
Summary: This study compares the success rates of establishing the access route, epinephrine administration rates, and time-to-epinephrine between adult patients with OHCA with IO access and those with IV access established by paramedics in the prehospital setting. The study found that IO access performed better than IV access in terms of success rates, epinephrine administration rates, and time-to-epinephrine.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2023)
Article
Critical Care Medicine
Kalin Kempster, Stuart Howell, Stephen Bernard, Karen Smith, Peter Cameron, Judith Finn, Dion Stub, Peter Morley, Janet Bray
Summary: The study found wide variation in survival between different EDs, which was associated with hospital characteristics. It suggests the need for a detailed review of ED deaths, particularly in non-cardiac arrest centres, and potentially the need for monitoring ED survival as a measure of quality.
Article
Critical Care Medicine
Kevin T. Schwalbach, Sylvia S. Yong, R. Chad Wade, Joseph Barney
Summary: During in-hospital cardiac arrest, intraosseous injection is associated with lower survival rates and lower rates of survival with favorable neurologic status compared to peripheral intravenous injection. Additionally, rates-of-ROSC and time-to-ROSC are longer with intraosseous injection.
Article
Critical Care Medicine
Kirstie L. Haywood, Chen Ji, Tom Quinn, Jerry P. Nolan, Charles D. Deakin, Charlotte Scomparin, Ranjit Lall, Simon Gates, John Long, Scott Regan, Rachael T. Fothergill, Helen Pocock, Nigel Rees, Lyndsey O'Shea, Gavin D. Perkins
Summary: The PARAMEDIC2 trial compared the effects of adrenaline on early outcomes in out-of-hospital cardiac arrest patients. Adrenaline improved survival up to 12 months follow-up but did not show evidence of improving favorable neurological outcomes. At 6 months, there was a slight increase in favorable neurological outcomes and survival in the adrenaline group compared to the placebo group.
Article
Critical Care Medicine
Sharvari Vadeyar, Alexandra Buckle, Amy Hooper, Scott Booth, Charles D. Deakin, Rachael Fothergill, Chen Ji, Jerry P. Nolan, Martina Brown, Alan Cowley, Emma Harris, Maureen Ince, Robert Marriott, John Pike, Robert Spaight, Gavin Perkins, Keith Couper
Summary: This study aimed to explore changes over time in the use of intraosseous and intravenous drug routes in out-of-hospital cardiac arrest in England. The results showed that the use of intraosseous access has progressively increased, while the use of intravenous access has decreased.
Article
Cardiac & Cardiovascular Systems
Purav Mody, Ambarish Pandey, Arthur S. Slutsky, Matthew W. Segar, Alex Kiss, Paul Dorian, Janet Parsons, Damon C. Scales, Valeria E. Rac, Sheldon Cheskes, Arlene S. Bierman, Beth L. Abramson, Sara Gray, Rob A. Fowler, Katie N. Dainty, Ahamed H. Idris, Laurie Morrison
Summary: Studies have shown that despite a higher likelihood of return of spontaneous circulation, women do not have higher survival rates after out-of-hospital cardiac arrest, especially among patients considered to have a favorable prognosis.
Article
Critical Care Medicine
Callahan Brebner, Michael Asamoah-Boaheng, Bianca Zaidel, Justin Yap, Frank Scheuermeyer, Valerie Mok, Michael Christian, Takahisa Kawano, Lovepreet Singh, Sean van Diepen, Jim Christenson, Brian Grunau
Summary: This study examined the association between using the humerus or tibia as the first-attempted vascular access site for out-of-hospital cardiac arrest and clinical outcomes. The results showed no significant association between the two sites and favorable neurological outcomes or survival at hospital discharge.
Article
Cardiac & Cardiovascular Systems
Carlo Alberto Barcella, Daniel Molager Christensen, Lars Idorn, Nishan Mudalige, Morten Malmborg, Frederik Folke, Christian Torp-Pedersen, Gunnar Gislason, Mohamad El-Chouli
Summary: This epidemiological study based on a registry found that patients with congenital heart disease (CHD) have a higher risk of out-of-hospital cardiac arrest (OHCA) compared to the general population. However, the 30-day survival rate for OHCA patients with CHD is similar to that of OHCA patients without CHD, and this survival relies on pre-hospital cardiopulmonary resuscitation and defibrillation.
EUROPEAN HEART JOURNAL
(2023)
Article
Critical Care Medicine
Mahshid Abir, Sydney Fouche, Jessica Lehrich, Jason Goldstick, Neil Kamdar, Michael O'Leary, Christopher Nelson, Peter Mendel, Wilson Nham, Claude Setodji, Robert Domeier, Anthony Hsu, Theresa Shields, Rama Salhi, Robert W. Neumar, Brahmajee K. Nallamothu
Summary: The study found substantial differences in sustained ROSC rates upon ED arrival across EMS agencies in Michigan, with an average adjusted rate of 23.8% but notable variation between agencies. The top five agencies had higher rates of sustained ROSC, while the bottom five had lower rates. These differences suggest opportunities for identifying and improving best practices in EMS agencies to enhance OHCA care.
Article
Health Care Sciences & Services
Yu Wang, Qun Zhang, Guang Bo Qu, Fang Fang, Xiao Kang Dai, Liang Xi Yu, Hong Zhang
Summary: This study evaluated the effects of advanced airway management (AAM) and adrenaline treatment on the outcomes of out-of-hospital cardiac arrest (OHCA) patients in China. The results showed that the combined treatment of AAM and adrenaline can increase the rate of return of spontaneous circulation (ROSC) and the rate of survival to admission in OHCA patients.
BMC HEALTH SERVICES RESEARCH
(2022)
Article
Critical Care Medicine
Ryan Huebinger, Veer Vithalani, Lesley Osborn, Cameron Decker, Jeff Jarvis, Robert Dickson, Mark Escott, Lynn White, Rabab Al-Araji, Peter Nikonowicz, Normandy Villa, Micah Panczyk, Henry Wang, Bentley Bobrow
Summary: The study found that compared to white neighborhoods, black neighborhoods had lower rates of AED use, Hispanic/Latino neighborhoods had lower rates of bystander CPR, AED use, and survival. Lower income was associated with lower rates of bystander CPR, AED use, and survival, lower high school graduation with lower rates of bystander CPR and AED use, and higher unemployment with lower rates of bystander CPR and AED use.
Article
Emergency Medicine
Jiri Karasek, Jiri Seiner, Metodej Renza, Frantisek Salanda, Martin Moudry, Matej Strycek, Jan Lejsek, Rostislav Polasek, Petr Ostadal
Summary: This study analyzed data from a regional CAC's prospective OHCA registry and found that patients transported to a CAC had significantly longer transport times, but hemodynamic parameters and outcomes were not affected.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Pedram Sultanian, Peter Lundgren, Anneli Stromsoe, Solveig Aune, Goran Bergstrom, Eva Hagberg, Jacob Hollenberg, Jonny Lindqvist, Therese Djarv, Albert Castelheim, Anna Thoren, Fredrik Hessulf, Leif Svensson, Andreas Claesson, Hans Friberg, Per Nordberg, Elmir Omerovic, Annika Rosengren, Johan Herlitz, Araz Rawshani
Summary: During the COVID-19 pandemic, cardiac arrest cases had higher mortality rates with COVID-19 positive cases compared to COVID-19 negative cases, both in OHCA and IHCA settings.
EUROPEAN HEART JOURNAL
(2021)