Structural insight into T cell coinhibition by PD-1H (VISTA)

Siglec-15 as an immune suppressor and potential target for normalization cancer immunotherapy

(2019) Jun Wang et al.   NATURE MEDICINE

Small-Molecule Immune Checkpoint Inhibitors Targeting PD-1/PD-L1 and Other Emerging Checkpoint Pathways

(2018) Pottayil G. Sasikumar et al.   BIODRUGS

A Paradigm Shift in Cancer Immunotherapy: From Enhancement to Normalization

(2018) Miguel F. Sanmamed et al.   CELL

UniProt: a worldwide hub of protein knowledge

(2018)   NUCLEIC ACIDS RESEARCH

The Pfam protein families database in 2019

(2018) Sara El-Gebali et al.   NUCLEIC ACIDS RESEARCH

High resolution X-ray and NMR structural study of human T-cell immunoglobulin and mucin domain containing protein-3

(2018) Amit K. Gandhi et al.   Scientific Reports

Blocking the VISTA pathway enhances disease progression in (NZB × NZW) F1 female mice

(2017) PA Sergent et al.   LUPUS

VISTA is an inhibitory immune checkpoint that is increased after ipilimumab therapy in patients with prostate cancer

(2017) Jianjun Gao et al.   NATURE MEDICINE

VISTA Deficiency Accelerates the Development of Fatal Murine Lupus Nephritis

(2017) Sabrina Ceeraz et al.   Arthritis & Rheumatology

Immune-checkpoint protein VISTA critically regulates the IL-23/IL-17 inflammatory axis

(2017) Na Li et al.   Scientific Reports

Initiation of T cell signaling by CD45 segregation at 'close contacts'

(2016) Veronica T Chang et al.   NATURE IMMUNOLOGY

Dali server update

(2016) Liisa Holm et al.   NUCLEIC ACIDS RESEARCH

Neuron-specific SALM5 limits inflammation in the CNS via its interaction with HVEM

(2016) Y. Zhu et al.   Science Advances

PD-1 Upregulated on Regulatory T Cells during Chronic Virus Infection Enhances the Suppression of CD8+T Cell Immune Response via the Interaction with PD-L1 Expressed on CD8+T Cells

(2015) Hyo Jin Park et al.   JOURNAL OF IMMUNOLOGY

Immune-checkpoint proteins VISTA and PD-1 nonredundantly regulate murine T-cell responses

(2015) Jun Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Control of signaling-mediated clearance of apoptotic cells by the tumor suppressor p53

(2015) K. W. Yoon et al.   SCIENCE

VISTA Regulates the Development of Protective Antitumor Immunity

(2014) I. Le Mercier et al.   CANCER RESEARCH

Coinhibitory receptor PD-1H preferentially suppresses CD4+ T cell–mediated immunity

(2014) Dallas B. Flies et al.   JOURNAL OF CLINICAL INVESTIGATION

Deciphering key features in protein structures with the new ENDscript server

(2014) Xavier Robert et al.   NUCLEIC ACIDS RESEARCH

Disruption of the immune-checkpoint VISTA gene imparts a proinflammatory phenotype with predisposition to the development of autoimmunity

(2014) L. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acidic extracellular microenvironment and cancer

(2013) Yasumasa Kato et al.   Cancer Cell International

The multiple roles of histidine in protein interactions

(2013) Si-Ming Liao et al.   Chemistry Central Journal

Evolution of the B7 family: co-evolution of B7H6 and NKp30, identification of a new B7 family member, B7H7, and of B7's historical relationship with the MHC

(2012) Martin F. Flajnik et al.   IMMUNOGENETICS

Cell Surface Signaling Molecules in the Control of Immune Responses: A Tide Model

(2011) Yuwen Zhu et al.   IMMUNITY

VISTA, a novel mouse Ig superfamily ligand that negatively regulates T cell responses

(2011) Li Wang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: A Monoclonal Antibody Specific for the Programmed Death-1 Homolog Prevents Graft-versus-Host Disease in Mouse Models

(2011) D. B. Flies et al.   JOURNAL OF IMMUNOLOGY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structural Basis of the CD8  /MHC Class I Interaction: Focused Recognition Orients CD8  to a T Cell Proximal Position

(2009) R. Wang et al.   JOURNAL OF IMMUNOLOGY

The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors

(2008) D. Y.-w. Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA