Chronic Dicer1 deficiency promotes atrophic and neovascular outer retinal pathologies in mice
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Chronic Dicer1 deficiency promotes atrophic and neovascular outer retinal pathologies in mice
Authors
Keywords
-
Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 117, Issue 5, Pages 2579-2587
Publisher
Proceedings of the National Academy of Sciences
Online
2020-01-22
DOI
10.1073/pnas.1909761117
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Transduction Patterns of Adeno-associated Viral Vectors in a Laser-Induced Choroidal Neovascularization Mouse Model
- (2018) Si Hyung Lee et al. Molecular Therapy-Methods & Clinical Development
- Delivery of CR2-fH Using AAV Vector Therapy as Treatment Strategy in the Mouse Model of Choroidal Neovascularization
- (2018) Gloriane Schnabolk et al. Molecular Therapy-Methods & Clinical Development
- MicroRNA-processing Enzymes Are Essential for Survival and Function of Mature Retinal Pigmented Epithelial Cells in Mice
- (2017) Thomas R. Sundermeier et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inflammatory signals from photoreceptor modulate pathological retinal angiogenesis via c-Fos
- (2017) Ye Sun et al. JOURNAL OF EXPERIMENTAL MEDICINE
- cGAS drives noncanonical-inflammasome activation in age-related macular degeneration
- (2017) Nagaraj Kerur et al. NATURE MEDICINE
- Sema3f Protects Against Subretinal Neovascularization In Vivo
- (2017) Ye Sun et al. EBioMedicine
- An easy, rapid method to isolate RPE cell protein from the mouse eye
- (2016) Hong Wei et al. EXPERIMENTAL EYE RESEARCH
- Geographic Atrophy and Choroidal Neovascularization in the Same Eye: A Review
- (2016) Patrick Kaszubski et al. OPHTHALMIC RESEARCH
- Re-evaluation of the roles ofDROSHA,Exportin 5, andDICERin microRNA biogenesis
- (2016) Young-Kook Kim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Distal retinal ganglion cell axon transport loss and activation of p38 MAPK stress pathway following VEGF-A antagonism
- (2016) R Foxton et al. Cell Death & Disease
- TRBP ensures efficient Dicer processing of precursor microRNA in RNA-crowded environments
- (2016) Mohamed Fareh et al. Nature Communications
- ReducedDICER1Expression Bestows Rheumatoid Arthritis Synoviocytes Proinflammatory Properties and Resistance to Apoptotic Stimuli
- (2016) Ghada Alsaleh et al. Arthritis & Rheumatology
- Novel CCR3 Antagonists Are Effective Mono- and Combination Inhibitors of Choroidal Neovascular Growth and Vascular Permeability
- (2015) Nori Nagai et al. AMERICAN JOURNAL OF PATHOLOGY
- AAV2 Delivery of Flt23k Intraceptors Inhibits Murine Choroidal Neovascularization
- (2015) Xiaohui Zhang et al. MOLECULAR THERAPY
- Production of functional small interfering RNAs by an amino-terminal deletion mutant of human Dicer
- (2015) Edward M. Kennedy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Increased Viral Dissemination in the Brain and Lethality in MCMV-Infected, Dicer-Deficient Neonates
- (2015) Eleonore Ostermann et al. Viruses-Basel
- MicroRNA-107 contributes to post-stroke angiogenesis by targeting Dicer-1
- (2015) Yanan Li et al. Scientific Reports
- Iron Toxicity in the Retina Requires Alu RNA and the NLRP3 Inflammasome
- (2015) Bradley D. Gelfand et al. Cell Reports
- Global microRNA depletion suppresses tumor angiogenesis
- (2014) S. Chen et al. GENES & DEVELOPMENT
- miRDB: an online resource for microRNA target prediction and functional annotations
- (2014) Nathan Wong et al. NUCLEIC ACIDS RESEARCH
- Characterization of a Spontaneous Retinal Neovascular Mouse Model
- (2014) Eiichi Hasegawa et al. PLoS One
- DICER1/AluRNA dysmetabolism induces Caspase-8–mediated cell death in age-related macular degeneration
- (2014) Younghee Kim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nucleoside reverse transcriptase inhibitors possess intrinsic anti-inflammatory activity
- (2014) B. J. Fowler et al. SCIENCE
- Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis
- (2014) Wan Ling Wong et al. Lancet Global Health
- Transfection of siRNAs can alter miRNA levels and trigger non-specific protein degradation in mammalian cells
- (2013) Xue-hai Liang et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- A Retrotransposon-Driven Dicer Isoform Directs Endogenous Small Interfering RNA Production in Mouse Oocytes
- (2013) Matyas Flemr et al. CELL
- Photoreceptor avascular privilege is shielded by soluble VEGF receptor-1
- (2013) Ling Luo et al. eLife
- MicroRNAs Regulate Tumor Angiogenesis Modulated by Endothelial Progenitor Cells
- (2012) P. N. Plummer et al. CANCER RESEARCH
- DICER1 Loss and Alu RNA Induce Age-Related Macular Degeneration via the NLRP3 Inflammasome and MyD88
- (2012) Valeria Tarallo et al. CELL
- In-vivo and ex-vivo characterization of laser-induced choroidal neovascularization variability in mice
- (2012) Robert Hoerster et al. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
- DICER- and AGO3-dependent generation of retinoic acid–induced DR2 Alu RNAs regulates human stem cell proliferation
- (2012) QiDong Hu et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Deregulation of Type I IFN-Dependent Genes Correlates with Increased Susceptibility to Cytomegalovirus Acute Infection of Dicer Mutant Mice
- (2012) Eleonore Ostermann et al. PLoS One
- Dicer-Dependent Biogenesis of Small RNAs Derived from 7SL RNA
- (2012) Yong-Feng Ren et al. PLoS One
- ERK1/2 activation is a therapeutic target in age-related macular degeneration
- (2012) S. Dridi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- In vivo structure-function analysis of human Dicer reveals directional processing of precursor miRNAs
- (2012) A. M. Gurtan et al. RNA
- Active role of small non-coding RNAs derived from SINE/B1 retrotransposon during early mouse development
- (2011) Yusuke Ohnishi et al. MOLECULAR BIOLOGY REPORTS
- Dicer recognizes the 5′ end of RNA for efficient and accurate processing
- (2011) Jong-Eun Park et al. NATURE
- DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration
- (2011) Hiroki Kaneko et al. NATURE
- Subretinal delivery of adeno-associated virus serotype 2 results in minimal immune responses that allow repeat vector administration in immunocompetent mice
- (2009) Susie E. Barker et al. JOURNAL OF GENE MEDICINE
- Effect of Genome Size on AAV Vector Packaging
- (2009) Zhijian Wu et al. MOLECULAR THERAPY
- Dicer Is Required for Maintaining Adult Pancreas
- (2009) Sumiyo Morita et al. PLoS One
- Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicer-dependent small RNAs
- (2008) J. E. Babiarz et al. GENES & DEVELOPMENT
- Impaired microRNA processing causes corpus luteum insufficiency and infertility in mice
- (2008) Motoyuki Otsuka et al. JOURNAL OF CLINICAL INVESTIGATION
- Autoinhibition of Human Dicer by Its Internal Helicase Domain
- (2008) Enbo Ma et al. JOURNAL OF MOLECULAR BIOLOGY
- Safety and Efficacy of Gene Transfer for Leber's Congenital Amaurosis
- (2008) Albert M. Maguire et al. NEW ENGLAND JOURNAL OF MEDICINE
- Effect of Gene Therapy on Visual Function in Leber's Congenital Amaurosis
- (2008) James W.B. Bainbridge et al. NEW ENGLAND JOURNAL OF MEDICINE
- Structural and biochemical insights into the dicing mechanism of mouse Dicer: A conserved lysine is critical for dsRNA cleavage
- (2008) Z. Du et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A search for conserved sequences in coding regions reveals that the let-7 microRNA targets Dicer within its coding sequence
- (2008) J. J. Forman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dicer-dependent endothelial microRNAs are necessary for postnatal angiogenesis
- (2008) Y. Suarez et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started