Global analysis of LARP1 translation targets reveals tunable and dynamic features of 5′ TOP motifs

Transcriptome-wide measurement of translation by ribosome profiling

(2017) Nicholas J. McGlincy et al.   METHODS

Autogenous Control of 5′TOP mRNA Stability by 40S Ribosomes

(2017) Antonio Gentilella et al.   MOLECULAR CELL

La-related protein 1 (LARP1) repression of TOP mRNA translation is mediated through its cap-binding domain and controlled by an adjacent regulatory region

(2017) Lucas Philippe et al.   NUCLEIC ACIDS RESEARCH

mTORC1 Balances Cellular Amino Acid Supply with Demand for Protein Synthesis through Post-transcriptional Control of ATF4

(2017) Yeonwoo Park et al.   Cell Reports

Cap-proximal nucleotides via differential eIF4E binding and alternative promoter usage mediate translational response to energy stress

(2017) Ana Tamarkin-Ben-Harush et al.   eLife

La-related protein 1 (LARP1) binds the mRNA cap, blocking eIF4F assembly on TOP mRNAs

(2017) Roni M Lahr et al.   eLife

The race to decipher the top secrets of TOP mRNAs

(2015) Oded Meyuhas et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

La-related Protein 1 (LARP1) Represses Terminal Oligopyrimidine (TOP) mRNA Translation Downstream of mTOR Complex 1 (mTORC1)

(2015) Bruno D. Fonseca et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gateways to the FANTOM5 promoter level mammalian expression atlas

(2015) Marina Lizio et al.   GENOME BIOLOGY

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Proteomic analysis of cap-dependent translation identifies LARP1 as a key regulator of 5'TOP mRNA translation

(2014) J. Tcherkezian et al.   GENES & DEVELOPMENT

Reassessment of the Role of TSC, mTORC1 and MicroRNAs in Amino Acids-Meditated Translational Control of TOP mRNAs

(2014) Ilona Patursky-Polischuk et al.   PLoS One

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

A unifying model for mTORC1-mediated regulation of mRNA translation

(2012) Carson C. Thoreen et al.   NATURE

The translational landscape of mTOR signalling steers cancer initiation and metastasis

(2012) Andrew C. Hsieh et al.   NATURE

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Efficient Solid-Phase Chemical Synthesis of 5′-Triphosphates of DNA, RNA, and their Analogues

(2010) Ivan Zlatev et al.   ORGANIC LETTERS

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets

(2009) Nahum Sonenberg et al.   CELL

An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1

(2009) Carson C. Thoreen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DBTSS provides a tissue specific dynamic view of Transcription Start Sites

(2009) Riu Yamashita et al.   NUCLEIC ACIDS RESEARCH

A comprehensive analysis of the La-motif protein superfamily

(2009) C. Bousquet-Antonelli et al.   RNA

A Base-Labile Group for 2′-OH Protection of Ribonucleosides: A Major Challenge for RNA Synthesis

(2008) Thomas Lavergne et al.   CHEMISTRY-A EUROPEAN JOURNAL

Comprehensive detection of human terminal oligo-pyrimidine (TOP) genes and analysis of their characteristics

(2008) Riu Yamashita et al.   NUCLEIC ACIDS RESEARCH