Scutellarin, a modulator of mTOR, attenuates hepatic insulin resistance by regulating hepatocyte lipid metabolism via SREBP‐1c suppression
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Title
Scutellarin, a modulator of mTOR, attenuates hepatic insulin resistance by regulating hepatocyte lipid metabolism via SREBP‐1c suppression
Authors
Keywords
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Journal
PHYTOTHERAPY RESEARCH
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2019-12-12
DOI
10.1002/ptr.6582
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Note: Only part of the references are listed.- CoMFA, CoMSIA, Topomer CoMFA, HQSAR, molecular docking and molecular dynamics simulations study of triazine morpholino derivatives as mTOR inhibitors for the treatment of breast cancer
- (2019) Dhara M. Chhatbar et al. COMPUTATIONAL BIOLOGY AND CHEMISTRY
- Molecular mechanisms of hepatic lipid accumulation in non-alcoholic fatty liver disease
- (2018) David Højland Ipsen et al. CELLULAR AND MOLECULAR LIFE SCIENCES
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- (2018) F. Phan et al. JOURNAL OF HEPATOLOGY
- In Vitro Comparative Study of the Inhibitory Effects of Mangiferin and Its Aglycone Norathyriol towards UDP-Glucuronosyl Transferase (UGT) Isoforms
- (2017) Dan Sun et al. MOLECULES
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- (2017) Erika Calvo-Ochoa et al. NEUROCHEMISTRY INTERNATIONAL
- The role of curcumin in disruption of HIF-1α accumulation to alleviate adipose fibrosis via AMPK-mediated mTOR pathway in high-fat diet fed mice
- (2017) Zhixia Qiu et al. Journal of Functional Foods
- Anti-hyperlipidemic effect of rice bran polysaccharide and its potential mechanism in high-fat diet mice
- (2017) Ying Nie et al. Food & Function
- mTORC1 signaling in hepatic lipid metabolism
- (2017) Jinbo Han et al. Protein & Cell
- Scutellarin Prevents Nonalcoholic Fatty Liver Disease (NAFLD) and Hyperlipidemia via PI3K/AKT-Dependent Activation of Nuclear Factor (Erythroid-Derived 2)-Like 2 (Nrf2) in Rats
- (2017) Hua Fan et al. MEDICAL SCIENCE MONITOR
- MHY1485 activates mTOR and protects osteoblasts from dexamethasone
- (2016) Sai Zhao et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Parkinsonia aculeata (Caesalpineaceae) improves high-fat diet-induced insulin resistance in mice through the enhancement of insulin signaling and mitochondrial biogenesis
- (2016) Tiago Gomes Araújo et al. JOURNAL OF ETHNOPHARMACOLOGY
- Targeting hepatic glucose metabolism in the treatment of type 2 diabetes
- (2016) Amy K. Rines et al. NATURE REVIEWS DRUG DISCOVERY
- Role of Hyperketonemia in Inducing Oxidative Stress and Cellular Damage in Cultured Hepatocytes and Type 1 Diabetic Rat Liver
- (2015) Preeti Kanikarla-Marie et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Role of hepatocyte S6K1 in palmitic acid-induced endoplasmic reticulum stress, lipotoxicity, insulin resistance and in oleic acid-induced protection
- (2015) Virginia Pardo et al. FOOD AND CHEMICAL TOXICOLOGY
- A New and Practical Synthetic Method for the Synthesis of 6-O-Methyl-scutellarein: One Metabolite of Scutellarin in Vivo
- (2015) Hang Lin et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Scutellarin from Scutellaria baicalensis Suppresses Adipogenesis by Upregulating PPARα in 3T3-L1 Cells
- (2013) Kaihui Lu et al. JOURNAL OF NATURAL PRODUCTS
- Antidiabetic Effects of Pterosin A, a Small-Molecular-Weight Natural Product, on Diabetic Mouse Models
- (2012) F.-L. Hsu et al. DIABETES
- Insulin stimulation of SREBP-1c processing in transgenic rat hepatocytes requires p70 S6-kinase
- (2012) J. L. Owen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway
- (2011) Timothy R. Peterson et al. CELL
- Akt Stimulates Hepatic SREBP1c and Lipogenesis through Parallel mTORC1-Dependent and Independent Pathways
- (2011) Jessica L. Yecies et al. Cell Metabolism
- Leucine Deprivation Increases Hepatic Insulin Sensitivity via GCN2/mTOR/S6K1 and AMPK Pathways
- (2011) Fei Xiao et al. DIABETES
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- (2011) Chin-Lin Hsu et al. Food & Function
- Mammalian Target of Rapamycin Complex 1 Suppresses Lipolysis, Stimulates Lipogenesis, and Promotes Fat Storage
- (2010) P. Chakrabarti et al. DIABETES
- Lipid-induced insulin resistance: unravelling the mechanism
- (2010) Varman T Samuel et al. LANCET
- Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis
- (2010) Shijie Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Imatinib Mesylate Reduces Endoplasmic Reticulum Stress and Induces Remission of Diabetes in db/db Mice
- (2009) M. S. Han et al. DIABETES
- Skeletal Muscle Insulin Resistance Is the Primary Defect in Type 2 Diabetes
- (2009) R. A. DeFronzo et al. DIABETES CARE
- Suppression of Diet-Induced Hypercholesterolemia by Scutellarin in Rats
- (2009) Qing Li et al. PLANTA MEDICA
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