4.2 Article

Gender and Age Determinants of Psychogenic Movement Disorders: A Clinical Profile of 73 Patients

Journal

CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES
Volume 43, Issue 2, Pages 268-277

Publisher

CAMBRIDGE UNIV PRESS
DOI: 10.1017/cjn.2015.365

Keywords

Dystonia; myoclonus; movement disorder; psychogenic; tremor

Funding

  1. Indian Council of Medical Research
  2. Department of Science and Technology
  3. Department of Biotechnology

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Background: Psychogenic movement disorders (PMD) is a group of disorders that cannot be attributed to any structural or biochemical abnormality, but has an underlying psychiatric illness. The profile of PMD varies according to country and socioeconomic factors. Methods: The present study reports the clinical profile of patients with PMD from India. Seventy-three patients with documented or clinically established PMD were seen over a period of 14 years with detailed neurological and psychiatric examinations. Results: The mean age at presentation was 29.115.1 years (women, 51%). Approximately 30% were 18 years of age (boys, 63.6%). The onset of symptoms was abrupt in 61.6% and the initial body part most often affected was right upper limb (adults, 29.4%; children, 31.8%). Tremor was observed in 31.4% of adults and 9% of children, whereas myoclonus was more common in children (36.4%). Tremors were more often seen in women (42.3%) than in men (20%), whereas myoclonus was almost equally prevalent in girls (37.5%) and boys (35.7%). Depression was the most common psychiatric comorbidity (men, 16%; women, 15.4%). About 42.5% required hospital admission and 57.5% had significant reduction or complete cessation of PMD after counseling, antidepressants, and/ or placebo. Conclusions: PMD was equally prevalent among women and men. Tremor was most often observed in adults, whereas myoclonus was most often observed in children. Electrophysiology and placebo were useful supplementary tools for diagnosing PMD.

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