Article
Medicine, General & Internal
Romain Vial, Marion Gully, Mickael Bobot, Violaine Scarfogliere, Philippe Brunet, Dammar Bouchouareb, Ariane Duval, He-oh Zino, Julien Faraut, Oceane Jehel, Yael Berdad-Haddad, Stephane Burtey, Pierre-Andre Jarrot, Guillaume Lano, Thomas Robert
Summary: Eosinophil count can serve as a rapid tool for screening symptomatic chronic hemodialysis patients suspected of COVID-19, with high sensitivity and specificity, facilitating quick diagnosis.
JOURNAL OF CLINICAL MEDICINE
(2021)
Editorial Material
Urology & Nephrology
Tony Lopez, Debasish Banerjee
Summary: Fluid overload is a common and important complication in patients with end-stage kidney failure receiving hemodialysis, leading to adverse outcomes, necessitating the search for accurate methods for assessing fluid status.
KIDNEY INTERNATIONAL
(2021)
Article
Respiratory System
Yanan Cui, Wenye Zhang, Yiming Ma, Zijie Zhan, Yan Chen
Summary: The study aimed to evaluate the stability of blood eosinophils in hospitalized acute exacerbation of COPD patients and found that changes in blood eosinophils are associated with outcomes during hospitalization and in the long term.
RESPIRATORY RESEARCH
(2021)
Article
Endocrinology & Metabolism
Ting Xiang, Ping Fu, Li Zhou
Summary: The aim of this study was to explore the prevalence of sarcopenia and its association with osteoporosis and to determine its impact on survival risk in hemodialysis patients. The study found a significant association between muscle mass and strength with bone density in hemodialysis patients, and those with osteosarcopenia had a higher mortality rate.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Biotechnology & Applied Microbiology
Ting-Yun Lin, Ping-Hsun Wu, Yi-Ting Lin, Szu-Chun Hung
Summary: The relationship between gut dysbiosis, inflammation, and adverse outcomes in chronic kidney disease patients is still unclear. Higher microbial diversity in hemodialysis patients is associated with a 74% lower risk of death. Nonsurvivors have lower microbial diversity and higher proinflammatory cytokine levels, with reduced abundance of certain beneficial bacteria like Succinivibrio and Anaerostipes.
NPJ BIOFILMS AND MICROBIOMES
(2021)
Article
Endocrinology & Metabolism
Hirotaka Komaba, Takayuki Hamano, Naohiko Fujii, Kensuke Moriwaki, Atsushi Wada, Ikuto Masakane, Kosaku Nitta, Masafumi Fukagawa
Summary: This study compared the risk of mortality between parathyroidectomy (PTx) and cinacalcet treatment in hemodialysis patients. The results showed that PTx resulted in greater reductions in intact PTH, calcium, and phosphorus levels compared with cinacalcet. PTx was associated with a lower risk of mortality, particularly among patients with severe secondary hyperparathyroidism.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Multidisciplinary Sciences
Kunihiro Ishioka, Sumi Hidaka, Naoki Fujiwara, Mizuki Yamano, Yasuhiro Mochida, Machiko Oka, Kyoko Maesato, Hidekazu Moriya, Takayasu Ohtake, Shuzo Kobayashi
Summary: This study investigated the association between zinc deficiency and aorta stiffness in non-diabetic HD patients. The results showed that patients in the zinc deficiency group were older and had higher levels of CRP and hypoalbuminemia. They also had higher levels of baPWV and lower levels of ABI. After adjusting for malnutrition and inflammation, multivariate analysis indicated that age and zinc level were independent predictors of baPWV.
Article
Medicine, General & Internal
Ana Mafalda Abrantes, Bernardo Marques da Silva, Carolina Branco, Claudia Costa, Nadiesda Peres, Ana Cardoso, Mariana Sant'Ana, Jose Agapito Fonseca, Cristina Outerelo, Cristina Resina, Jose Antonio Lopes, Joana Gameiro
Summary: This study aimed to evaluate the CHA2DS2-VASc score as a tool for predicting one-year mortality after hemodialysis initiation and identifying factors associated with higher mortality. The results showed that patients with higher CHA2DS2-VASc scores had higher mortality rates, and the score could predict one-year mortality risk well. Additionally, a CHA2DS2-VASc score ≥3.5 and the use of central venous catheter at hemodialysis initiation were significant predictors of one-year mortality.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Biochemistry & Molecular Biology
Seok-Hui Kang, Bo-Yeon Kim, Eun-Jung Son, Gui-Ok Kim, Jun-Young Do
Summary: The study aimed to evaluate the effect of different types of beta-blockers on patient survival in hemodialysis. The results showed no significant difference in patient survival based on the use or types of beta-blockers.
Article
Nutrition & Dietetics
M. Luz Sanchez-Tocino, Blanca Miranda-Serrano, Antonio Lopez-Gonzalez, Silvia Villoria-Gonzalez, Monica Pereira-Garcia, Carolina Gracia-Iguacel, Isabel Gonzalez-Ibarguren, Alberto Ortiz-Arduan, Sebastian Mas-Fontao, Emilio Gonzalez-Parra
Summary: This study demonstrates an association between sarcopenia defined by the Working Group on Sarcopenia in Older People (EWGSOP2) diagnostic criteria and mortality in very elderly hemodialysis patients at 24 months.
Article
Medicine, Research & Experimental
Chun Zhou, Yuanyuan Zhang, Jianghua Chen, Changlin Mei, Fei Xiong, Wei Shi, Wei Zhou, Xusheng Liu, Shiren Sun, Jianwei Tian, Ziliang Ye, Qimeng Wu, Xianhui Qin, Jianping Jiang, Fan Fan Hou
Summary: This study aimed to assess the correlation of serum advanced oxidation protein products (AOPP) levels with the risk of all-cause mortality in hemodialysis (HD) patients in China. The results showed that elevated serum AOPP levels were associated with a higher risk of all-cause mortality in Chinese maintenance HD patients, particularly in those with AOPP levels >=87 mu mol/L.
JOURNAL OF TRANSLATIONAL MEDICINE
(2021)
Article
Computer Science, Interdisciplinary Applications
Yu Wang, Yilin Zhu, Guofeng Lou, Ping Zhang, Jianghua Chen, Jingsong Li
Summary: This study proposed a method for predicting the mortality of HD patients using longitudinal HD data, utilizing the LSTM AE model and anomaly detection theory to identify high-risk patients in an imbalanced dataset caused by lost to follow-up.
JOURNAL OF BIOMEDICAL INFORMATICS
(2021)
Article
Medicine, General & Internal
Seok-Hui Kang, Gui-Ok Kim, Bo-Yeon Kim, Eun-Jung Son, Jun-Young Do
Summary: This study investigated the effect of statin solubility on the survival of hemodialysis patients. The retrospective study found that patients taking lipophilic statins had a higher survival rate compared to those who did not receive statins.
Review
Immunology
Elizabeth A. Jacobsen, David J. Jackson, Enrico Heffler, Sameer K. Mathur, Albert J. Bredenoord, Ian D. Pavord, Praveen Akuthota, Florence Roufosse, Marc E. Rothenberg
Summary: Research on manipulating mouse and human eosinophils through experimental systems has made significant progress in revealing their roles in the immune system. Anti-eosinophil therapeutics have emerged as a new class of drugs, offering valuable insights into the consequences of eosinophil knockout in humans.
ANNUAL REVIEW OF IMMUNOLOGY, VOL 39
(2021)
Review
Public, Environmental & Occupational Health
Fan Zhang, Hui Wang, Weiqiong Wang, Huachun Zhang
Summary: Physical activity is related to improved outcomes in hemodialysis patients, and promoting physical activity can be an important approach to improving cardiovascular health and clinical outcomes.
FRONTIERS IN PUBLIC HEALTH
(2022)
Review
Urology & Nephrology
Rajiv Agarwal, James Burton, Maurizio Gallieni, Kamyar Kalantar-Zadeh, Gert Mayer, Carol Pollock, Jacek C. Szepietowski
Summary: Despite the limited increase in life expectancy for patients with end-stage kidney disease after the breakthrough of kidney replacement therapy, the quality of life and relief of symptoms have become increasingly important to patients. Currently, most dialysis-associated symptoms and adverse effects do not have approved treatments, and the few available treatments may add further adverse effects. This article demonstrates how understanding the pathophysiology of a particular symptom (chronic kidney disease-associated pruritus) in dialysis led to the development and regulatory approval of a treatment for that symptom. This approach can be applied to other dialysis-associated symptoms, improving the remaining years of patients' lives.
CLINICAL KIDNEY JOURNAL
(2023)
Editorial Material
Urology & Nephrology
Ekamol Tantisattamo, Ramy M. Hanna, Kamyar Kalantar-Zadeh
CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION
(2023)
Review
Urology & Nephrology
Ramy M. M. Hanna, Rebecca S. S. Ahdoot, Connie M. M. Rhee, Ekamol Tantisattamo, Fawaz Al Ammar, Kamyar Kalantar-Zadeh
Summary: A low protein diet is often recommended for the nutritional management of chronic kidney disease, but there is a need for more exploration of dietary recommendations for different types of renal patients. Proteinuria is a serious issue for renal disease patients, and nutritional strategies need to be explored to control proteinuria and inflammation, which is of great significance for the treatment of autoimmune kidney diseases such as glomerulonephritis.
CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION
(2023)
Review
Urology & Nephrology
Dawn P. Edwards, Kamyar Kalantar-Zadeh, Elani Streja, Rebecca S. Ahdoot, Keith C. Norris, Donald Molony
CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION
(2023)
Review
Urology & Nephrology
Fawaz Al Ammary, Abimereki D. Muzaale, Ekamol Tantisattamoa, Ramy M. Hanna, Uttam G. Reddy, Suphamai Bunnapradist, Kamyar Kalantar-Zadeh
Summary: There has been a decrease in living kidney donation over the past two decades, particularly among low-income families and racial/ethnic minorities who face barriers to completing complex evaluations. Telemedicine, specifically the use of live-video visits, is seen as a potential solution to overcome these barriers and improve access to transplant centers for donor evaluation. However, providers perceive payor policy and out-of-state licensing as major obstacles to the growth of telemedicine.
CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION
(2023)
Review
Urology & Nephrology
Maria Clarissa Tio, Tariq Shafi, Xiaoqian Zhu, Kamyar Kalantar-Zadeh, Alexandre Chan, Lee Nguyen
Summary: This review focuses on the evolution of GFR estimating equations, nuances in eGFR interpretation, and the utility of eGFR in drug dosing.
CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION
(2023)
Review
Urology & Nephrology
Ekamol Tantisattamo, Kamyar Kalantar-Zadeh
Summary: Living donor kidney transplantation may lead to long-term complications, but dietary interventions have the potential to prevent them and improve the health outcomes of donors. Low protein and low sodium intake, as well as certain healthy dietary patterns, may help slow down the decline in kidney function. However, further research is needed to determine the optimal protein and sodium intake as well as the appropriate dietary patterns for living kidney donors.
CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION
(2023)
Review
Peripheral Vascular Disease
Takahiko Nakagawa, Ana Andres-Hernando, Tomoki G. Kosugi, Laura Sanchez-Lozada, Peter Stenvinkel, Karolina Kublickiene, S. Ananth Karumanchi, Duk-Hee Kang, Hideto Kojima, Bernardo R. Rodriguez-Iturbe, Dean A. Tolan, Miguel J. Lanaspa, Richard Johnson
Summary: Preeclampsia is a hypertensive disorder of pregnancy caused by abnormal placentation. Fructose, which plays a critical role in fetal growth, is produced in the placenta during early pregnancy to assist fetal survival in a hypoxic environment. Impaired placentation leads to excessive fructose production, which drives various pathological features of preeclampsia. In addition, dietary fructose intake has been identified as an independent risk factor for preeclampsia.
HYPERTENSION RESEARCH
(2023)
Editorial Material
Peripheral Vascular Disease
Takahiko Nakagawa, Duk-Hee Kang, Richard J. J. Johnson
HYPERTENSION RESEARCH
(2023)
Article
Nutrition & Dietetics
Yoshikazu Miyasato, Ramy M. Hanna, Jun Morinaga, Masashi Mukoyama, Kamyar Kalantar-Zadeh
Summary: Prognostic nutritional index (PNI), calculated from serum albumin level and total lymphocyte count, is a useful prognostic marker for both cancer patients and patients undergoing hemodialysis.
Editorial Material
Nutrition & Dietetics
Kamyar Kalantar-Zadeh, Rachelle Bross, Christina Wang, Linda W. Moore
JOURNAL OF RENAL NUTRITION
(2023)
Article
Transplantation
Juan Carlos Ayus, Kamyar Kalantar-Zadeh, Ekamol Tantisattamo, Connie M. Rhee, Armando L. Negri
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2023)
Editorial Material
Urology & Nephrology
Ahmet Murt, Kamyar Kalantar-Zadeh
CLINICAL KIDNEY JOURNAL
(2023)
Article
Urology & Nephrology
Connie M. M. Rhee, Amy S. S. You, Victoria Page, Glen Hayashida, Merle Kataoka-Yahiro, James Davis, Linda L. L. Wong, Yoko Narasaki, Kamyar Kalantar-Zadeh
Summary: Several studies suggest that Asian-American and NHOPI racial/ethnic groups have a heightened risk of CKD, but provide limited inference due to the aggregation of these groups. In this study, we examined the association of granularly defined racial/ethnic groups with specific CKD indicators among a diverse group of participants.
Article
Pharmacology & Pharmacy
Praveen K. Potukuchi, Hamid Moradi, Frank Park, Cameron Kaplan, Fridtjof Thomas, Ankur A. Dashputre, Keiichi Sumida, Miklos Z. Molnar, Abduzhappar Gaipov, Justin D. Gatwood, Connie Rhee, Elani Streja, Kamyar Kalantar-Zadeh, Csaba P. Kovesdy
Summary: This observational study found no association between cannabis use and the risk of acute kidney injury in patients with advanced chronic kidney disease.
CANNABIS AND CANNABINOID RESEARCH
(2023)