Triglyceride-lowering effect of the aldose reductase inhibitor cemtirestat—another factor that may contribute to attenuation of symptoms of peripheral neuropathy in STZ-diabetic rats

3-Mercapto-5H-1,2,4-Triazino[5,6-b]Indole-5-Acetic Acid (Cemtirestat) Alleviates Symptoms of Peripheral Diabetic Neuropathy in Zucker Diabetic Fatty (ZDF) Rats: A Role of Aldose Reductase

(2019) Marta Soltesova Prnova et al.   NEUROCHEMICAL RESEARCH

Exploring the interactional details between aldose reductase (AKR1B1) and 3-Mercapto-5H-1,2,4-triazino[5,6-b]indole-5-acetic acid through molecular dynamics simulations

(2018) Jiu-Yu Zhan et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Identification of Novel Aldose Reductase Inhibitors Based on Carboxymethylated Mercaptotriazinoindole Scaffold

(2015) Milan Stefek et al.   JOURNAL OF MEDICINAL CHEMISTRY

Updates on Aldose Reductase Inhibitors for Management of Diabetic Complications and Non-diabetic Diseases

(2015) Ajmer Singh Grewal et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

A streptozotocin-induced diabetic neuropathic pain model for static or dynamic mechanical allodynia and vulvodynia: validation using topical and systemic gabapentin

(2015) Gowhar Ali et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Targeting Aldose Reductase for the Treatment of Diabetes Complications and Inflammatory Diseases: New Insights and Future Directions

(2014) Rosanna Maccari et al.   JOURNAL OF MEDICINAL CHEMISTRY

Phenotyping animal models of diabetic neuropathy: a consensus statement of the diabetic neuropathy study group of the EASD (Neurodiab)

(2014) G.J. Biessels et al.   JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM

Optimal interval for hot water immersion tail-flick test in rats

(2013) Quanhong Zhou et al.   ACTA NEUROPSYCHIATRICA

The Effects of Atorvastatin Therapy on Rheological Characteristics of Erythrocyte Membrane, Serum Lipid Profile and Oxidative Status in Patients with Dyslipidemia

(2012) Hüseyin Avni Uydu et al.   JOURNAL OF MEMBRANE BIOLOGY

Inhibition of Aldose Reductase Activates Hepatic Peroxisome Proliferator-Activated Receptor-αand Ameliorates Hepatosteatosis in Diabetic db/db Mice

(2011) Longxin Qiu et al.   Experimental Diabetes Research

PARP inhibition alleviates diabetes-induced systemic oxidative stress and neural tissue 4-hydroxynonenal adduct accumulation: Correlation with peripheral nerve function

(2011) Sergey Lupachyk et al.   FREE RADICAL BIOLOGY AND MEDICINE

Animal models and biomarkers of neuropathy in diabetic rodents

(2010) RS Somani et al.   INDIAN JOURNAL OF PHARMACOLOGY

The Eurodiab study: What has this taught us about diabetic peripheral neuropathy?

(2009) Solomon Tesfaye et al.   Current Diabetes Reports

Aldose Reductase Enzyme and its Implication to Major Health Problems of the 21st Century

(2009) Polyxeni Alexiou et al.   CURRENT MEDICINAL CHEMISTRY

Elevated Triglycerides Correlate With Progression of Diabetic Neuropathy

(2009) T. D. Wiggin et al.   DIABETES

Aldose Reductase, Still a Compelling Target for Diabetic Neuropathy

(2008) Peter Oates   CURRENT DRUG TARGETS

PARP inhibition or gene deficiency counteracts intraepidermal nerve fiber loss and neuropathic pain in advanced diabetic neuropathy

(2007) Irina G. Obrosova et al.   FREE RADICAL BIOLOGY AND MEDICINE

Glucose neurotoxicity

(2007) David R. Tomlinson et al.   NATURE REVIEWS NEUROSCIENCE