Cryo-EM structures of the ionotropic glutamate receptor GluD1 reveal a non-swapped architecture

Mechanisms underlying the synaptic trafficking of the glutamate delta receptor GluD1

(2019) Wucheng Tao et al.   MOLECULAR PSYCHIATRY

Architecture and subunit arrangement of native AMPA receptors elucidated by cryo-EM

(2019) Yan Zhao et al.   SCIENCE

CM01: a facility for cryo-electron microscopy at the European Synchrotron

(2019) Eaazhisai Kandiah et al.   Acta Crystallographica Section D-Structural Biology

Namdinator – automatic molecular dynamics flexible fitting of structural models into cryo-EM and crystallography experimental maps

(2019) Rune Thomas Kidmose et al.   IUCrJ

Structural biology of glutamate receptor ion channels: towards an understanding of mechanism

(2019) Ingo H Greger et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Postsynaptic δ1 glutamate receptor assembles and maintains hippocampal synapses via Cbln2 and neurexin

(2018) Wucheng Tao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Real-space refinement in PHENIX for cryo-EM and crystallography

(2018) Pavel V. Afonine et al.   Acta Crystallographica Section D-Structural Biology

Mechanism of NMDA receptor channel block by MK-801 and memantine

(2018) Xianqiang Song et al.   NATURE

Mechanisms for Zinc and Proton Inhibition of the GluN1/GluN2A NMDA Receptor

(2018) Farzad Jalali-Yazdi et al.   CELL

GluD1, linked to schizophrenia, controls the burst firing of dopamine neurons

(2017) N Benamer et al.   MOLECULAR PSYCHIATRY

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination

(2017) Ali Punjani et al.   NATURE METHODS

Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes

(2017) Edward C. Twomey et al.   NEURON

mGlu1 receptor canonical signaling pathway contributes to the opening of the orphan GluD2 receptor

(2017) Selma Dadak et al.   NEUROPHARMACOLOGY

A GluD Coming-Of-Age Story

(2017) Michisuke Yuzaki et al.   TRENDS IN NEUROSCIENCES

Preferential assembly of heteromeric kainate and AMPA receptor amino terminal domains

(2017) Huaying Zhao et al.   eLife

Gctf: Real-time CTF determination and correction

(2016) Kai Zhang   JOURNAL OF STRUCTURAL BIOLOGY

Transsynaptic Modulation of Kainate Receptor Functions by C1q-like Proteins

(2016) Keiko Matsuda et al.   NEURON

Structural basis for integration of GluD receptors within synaptic organizer complexes

(2016) Jonathan Elegheert et al.   SCIENCE

Conformational Plasticity in the Transsynaptic Neurexin-Cerebellin-Glutamate Receptor Adhesion Complex

(2016) Shouqiang Cheng et al.   STRUCTURE

Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States

(2014) Katharina L. Dürr et al.   CELL

Early-onset autosomal recessive cerebellar ataxia associated with retinal dystrophy: new human hotfoot phenotype caused by homozygous GRID2 deletion

(2014) Kristof Van Schil et al.   GENETICS IN MEDICINE

Structural mechanism of glutamate receptor activation and desensitization

(2014) Joel R. Meyerson et al.   NATURE

Screening and large-scale expression of membrane proteins in mammalian cells for structural studies

(2014) April Goehring et al.   Nature Protocols

A New Mouse Allele of Glutamate Receptor Delta 2 with Cerebellar Atrophy and Progressive Ataxia

(2014) Yuka Miyoshi et al.   PLoS One

Type 1 metabotropic glutamate receptors (mGlu1) trigger the gating of GluD2 delta glutamate receptors

(2013) Visou Ady et al.   EMBO REPORTS

The delta subfamily of glutamate receptors: characterization of receptor chimeras and mutants

(2013) Angela Orth et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

A Homozygous Deletion in GRID2 Causes a Human Phenotype With Cerebellar Ataxia and Atrophy

(2013) G. Eda Utine et al.   JOURNAL OF CHILD NEUROLOGY

Analysis of high-affinity assembly for AMPA receptor amino-terminal domains

(2013) Huaying Zhao et al.   JOURNAL OF GENERAL PHYSIOLOGY

The  2 glutamate receptor gates long-term depression by coordinating interactions between two AMPA receptor phosphorylation sites

(2013) K. Kohda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GluR 2 Assembles Four Neurexins into Trans-Synaptic Triad to Trigger Synapse Formation

(2012) S.-J. Lee et al.   JOURNAL OF NEUROSCIENCE

Prevention of overfitting in cryo-EM structure determination

(2012) Sjors H W Scheres et al.   NATURE METHODS

Deletion of Glutamate Delta-1 Receptor in Mouse Leads to Aberrant Emotional and Social Behaviors

(2012) Roopali Yadav et al.   PLoS One

Mutations in the transmembrane domain M3 generate spontaneously open orphan glutamate delta 1 receptor

(2011) Roopali Yadav et al.   BRAIN RESEARCH

Glutamate receptor δ1 induces preferentially inhibitory presynaptic differentiation of cortical neurons by interacting with neurexins through cerebellin precursor protein subtypes

(2011) Misato Yasumura et al.   JOURNAL OF NEUROCHEMISTRY

Trans-Synaptic Interaction of GluRδ2 and Neurexin through Cbln1 Mediates Synapse Formation in the Cerebellum

(2010) Takeshi Uemura et al.   CELL

Contribution of the Global Subunit Structure and Stargazin on the Maturation of AMPA Receptors

(2010) N. F. Shanks et al.   JOURNAL OF NEUROSCIENCE

Cbln1 Is a Ligand for an Orphan Glutamate Receptor  2, a Bidirectional Synapse Organizer

(2010) K. Matsuda et al.   SCIENCE

Modulation of the Dimer Interface at Ionotropic Glutamate-Like Receptor  2 by D-Serine and Extracellular Calcium

(2009) K. B. Hansen et al.   JOURNAL OF NEUROSCIENCE

X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor

(2009) Alexander I. Sobolevsky et al.   NATURE

The glutamate receptor subunit delta2 is capable of gating its intrinsic ion channel as revealed by ligand binding domain transplantation

(2009) S. M. Schmid et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Energetics of glutamate receptor ligand binding domain dimer assembly are modulated by allosteric ions

(2009) C. Chaudhry et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct Interaction Enables Cross-talk between Ionotropic and Group I Metabotropic Glutamate Receptors

(2008) Julie Perroy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

To Gate or not to Gate: Are the Delta Subunits in the Glutamate Receptor Family Functional Ion Channels?

(2008) Sabine M. Schmid et al.   MOLECULAR NEUROBIOLOGY