Therapy-induced senescence — an induced synthetic lethality in liver cancer?

Inducing and exploiting vulnerabilities for the treatment of liver cancer

(2019) Cun Wang et al.   NATURE

Synthetic lethality as an engine for cancer drug target discovery

(2019) Alan Huang et al.   NATURE REVIEWS DRUG DISCOVERY

Senescent cells: an emerging target for diseases of ageing

(2017) Bennett G. Childs et al.   NATURE REVIEWS DRUG DISCOVERY

Cellular senescence in gastrointestinal diseases: from pathogenesis to therapeutics

(2017) Nina Frey et al.   Nature Reviews Gastroenterology & Hepatology

Distinct Functions of Senescence-Associated Immune Responses in Liver Tumor Surveillance and Tumor Progression

(2016) Tobias Eggert et al.   CANCER CELL

Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice

(2015) Jianhui Chang et al.   NATURE MEDICINE

Enhancing Chemotherapy Efficacy in Pten -Deficient Prostate Tumors by Activating the Senescence-Associated Antitumor Immunity

(2014) Alberto Toso et al.   Cell Reports

Tumour heterogeneity in the clinic

(2013) Philippe L. Bedard et al.   NATURE

Senescence surveillance of pre-malignant hepatocytes limits liver cancer development

(2011) Tae-Won Kang et al.   NATURE