In Silico, Ex Vivo and In Vivo Studies of Roflumilast as a Potential Antidiarrheal and Antispasmodic agent: Inhibition of the PDE-4 Enzyme and Voltage-gated Ca++ ion Channels

Roflumilast, a phosphodiesterase 4 inhibitor, attenuates cadmium-induced renal toxicity via modulation of NF-κB activation and induction of NQO1 in rats

(2019) MN Ansari et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Protective role of Roflumilast against cadmium-induced cardiotoxicity through inhibition of oxidative stress and NF-κB signaling in rats

(2019) Mohd Nazam Ansari et al.   SAUDI PHARMACEUTICAL JOURNAL

Do Halogen–Hydrogen Bond Donor Interactions Dominate the Favorable Contribution of Halogens to Ligand–Protein Binding?

(2017) Fang-Yu Lin et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Apremilast reversed carfilzomib-induced cardiotoxicity through inhibition of oxidative stress, NF-κB and MAPK signaling in rats

(2016) Faisal Imam et al.   TOXICOLOGY MECHANISMS AND METHODS

Apremilast reversed carfilzomib-induced cardiotoxicity through inhibition of oxidative stress, NF-κB and MAPK signaling in rats

(2016) Faisal Imam et al.   TOXICOLOGY MECHANISMS AND METHODS

Antidiarrheal effect of Alpinia oxyphylla Miq. (Zingiberaceae) in experimental mice and its possible mechanism of action

(2015) Sheng Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Antidiarrheal and Antispasmodic Activities ofBuddleja polystachyaare Mediated Through Dual Inhibition of Ca++Influx and Phosphodiesterase Enzyme

(2015) Najeeb-ur Rehman et al.   PHYTOTHERAPY RESEARCH

Pharmacological Basis for Medicinal Use ofLens culinarisin Gastrointestinal and Respiratory Disorders

(2014) Munasib Khan et al.   PHYTOTHERAPY RESEARCH

Pathogenesis of adherent–invasiveEscherichia coli

(2013) Emma J Smith et al.   Future Microbiology

Pharmacological basis for the medicinal use of Psidium guajava leave in hyperactive gut disorders

(2012) Abdul Jabbar Shah et al.   Bangladesh Journal of Pharmacology

Medicinal plants used by the Bapedi traditional healers to treat diarrhoea in the Limpopo Province, South Africa

(2012) S.S. Semenya et al.   JOURNAL OF ETHNOPHARMACOLOGY

Species Differences in the Antidiarrheal and Antispasmodic Activities ofLepidium sativumand Insight into Underlying Mechanisms

(2012) Anwarul-Hassan Gilani et al.   PHYTOTHERAPY RESEARCH

Antispasmodic and Antidiarrheal Activities ofValeriana hardwickiiWall. Rhizome Are Putatively Mediated through Calcium Channel Blockade

(2011) Samra Bashir et al.   Evidence-based Complementary and Alternative Medicine

The role of cAMP regulation in controlling inflammation

(2010) A. R. MOORE et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Bacterial Enteropathogens and Risk Factors Associated with Childhood Diarrhea

(2010) Abdel Moati Kh. Al Jarousha et al.   INDIAN JOURNAL OF PEDIATRICS

Antidiarrheal activity of ethanolic bark extract of Mitragyna diversifolia

(2009) Jebunnessa et al.   Bangladesh Journal of Pharmacology

New Clinical Method for Distinguishing D-IBS from Other Gastrointestinal Conditions Causing Diarrhea: The LA/IBS Diagnostic Strategy

(2009) Mark Pimentel et al.   DIGESTIVE DISEASES AND SCIENCES

Phosphodiesterase inhibitors

(2006) Victoria Boswell-Smith et al.   BRITISH JOURNAL OF PHARMACOLOGY