Probing Reversible Guest Binding with Hyperpolarized 129Xe-NMR: Characteristics and Applications for Cucurbit[n]urils

Dynamic Interactions in Synthetic Receptors: A Guest Exchange Saturation Transfer Study

(2019) Liat Avram et al.   CHEMISTRY-A EUROPEAN JOURNAL

Assessment of brain perfusion using hyperpolarized 129 Xe MRI in a subject with established stroke

(2019) Madhwesha R. Rao et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

pH-Responsive Pillar[6]arene-based Water-Soluble Supramolecular Hexagonal Boxes

(2019) Dana Kaizerman-Kane et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rotaxane probes for the detection of hydrogen peroxide by 129Xe hyperCEST NMR

(2019) Sarah H. Klass et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Directly Functionalized Cucurbit[7]uril as a Biosensor for the Selective Detection of Protein Interactions by 129 Xe hyperCEST NMR

(2019) Ashley E. Truxal et al.   CHEMISTRY-A EUROPEAN JOURNAL

Facile Preparation of Cucurbit[6]uril-Based Polymer Nanocapsules for Targeted Photodynamic Therapy

(2019) Chen Sun et al.   ACS Applied Materials & Interfaces

Dissolved hyperpolarized xenon‐129 MRI in human kidneys

(2019) Jorge Chacon‐Caldera et al.   MAGNETIC RESONANCE IN MEDICINE

Applications of Cucurbiturils in Medicinal Chemistry and Chemical Biology

(2019) Debapratim Das et al.   Frontiers in Chemistry

Nanoparticle-Based Contrast Agents for 129Xe HyperCEST NMR and MRI Applications

(2019) Jabadurai Jayapaul et al.   Contrast Media & Molecular Imaging

Quantitative Assessment of Xenon Exchange Kinetics with Cucurbit[6]uril in Physiological Saline

(2018) Sergey Korchak et al.   CHEMPHYSCHEM

Pillar[n ]arenes at the Chemistry-Biology Interface

(2018) Peter J. Cragg   ISRAEL JOURNAL OF CHEMISTRY

Time-resolved monitoring of enzyme activity with ultrafast Hyper-CEST spectroscopy

(2018) Jörg Döpfert et al.   MAGNETIC RESONANCE IN CHEMISTRY

Imaging Human Brain Perfusion with Inhaled Hyperpolarized 129Xe MR Imaging

(2018) Madhwesha R. Rao et al.   RADIOLOGY

Supramolecular latching system based on ultrastable synthetic binding pairs as versatile tools for protein imaging

(2018) Kyung Lock Kim et al.   Nature Communications

High Exchange Rate Complexes of 129 Xe with Water-Soluble Pillar[5]arenes for Adjustable Magnetization Transfer MRI

(2018) Matthias Schnurr et al.   CHEMPHYSCHEM

Precise supramolecular control of surface coverage densities on polymer micro- and nanoparticles

(2018) Shuai Zhang et al.   Chemical Science

Evaluation of Three Morphologically Distinct Virus-Like Particles as Nanocarriers for Convection-Enhanced Drug Delivery to Glioblastoma

(2018) Joel Finbloom et al.   Nanomaterials

HYDROPHOBE Challenge: A Joint Experimental and Computational Study on the Host–Guest Binding of Hydrocarbons to Cucurbiturils, Allowing Explicit Evaluation of Guest Hydration Free-Energy Contributions

(2017) Khaleel I. Assaf et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Cucurbit[6]uril-Promoted Click Chemistry for Protein Modification

(2017) Joel A. Finbloom et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Preparation of biogenic gas vesicle nanostructures for use as contrast agents for ultrasound and MRI

(2017) Anupama Lakshmanan et al.   Nature Protocols

In situ generated D‐peptidic nanofibrils as multifaceted apoptotic inducers to target cancer cells

(2017) Xuewen Du et al.   Cell Death & Disease

In vivo detection of cucurbit[6]uril, a hyperpolarized xenon contrast agent for a xenon magnetic resonance imaging biosensor

(2017) Francis T. Hane et al.   Scientific Reports

Diamagnetic Imaging Agents with a Modular Chemical Design for Quantitative Detection of β-Galactosidase and β-Glucuronidase Activities with CatalyCEST MRI

(2016) Gabriela Fernández-Cuervo et al.   BIOCONJUGATE CHEMISTRY

A CatalyCEST MRI Contrast Agent that Can Simultaneously Detect Two Enzyme Activities

(2016) Gabriela Fernández-Cuervo et al.   CHEMBIOCHEM

Rotaxane-mediated suppression and activation of cucurbit[6]uril for molecular detection by 129Xe hyperCEST NMR

(2016) Joel A. Finbloom et al.   CHEMICAL COMMUNICATIONS

Detection of Sulfatase Enzyme Activity with a CatalyCEST MRI Contrast Agent

(2016) Sanhita Sinharay et al.   CHEMISTRY-A EUROPEAN JOURNAL

Design and comparison of exchange spectroscopy approaches to cryptophane–xenon host–guest kinetics

(2016) Sergey Korchak et al.   JOURNAL OF MAGNETIC RESONANCE

15N Heteronuclear Chemical Exchange Saturation Transfer MRI

(2016) Haifeng Zeng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Integrating Enzymatic Self-Assembly and Mitochondria Targeting for Selectively Killing Cancer Cells without Acquired Drug Resistance

(2016) Huaimin Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enzyme-Regulated Supramolecular Assemblies of Cholesterol Conjugates against Drug-Resistant Ovarian Cancer Cells

(2016) Huaimin Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

High resolution spectroscopy and chemical shift imaging of hyperpolarized129Xe dissolved in the human brain in vivo at 1.5 tesla

(2016) Madhwesha Rao et al.   MAGNETIC RESONANCE IN MEDICINE

Noninvasive detection of enzyme activity in tumor models of human ovarian cancer using catalyCEST MRI

(2016) Sanhita Sinharay et al.   MAGNETIC RESONANCE IN MEDICINE

Amplifying undetectable NMR signals to study host–guest interactions and exchange

(2016) Liat Avram et al.   Chemical Science

Supramolecular Assays for Mapping Enzyme Activity by Displacement-Triggered Change in Hyperpolarized129Xe Magnetization Transfer NMR Spectroscopy

(2015) Matthias Schnurr et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enzyme-Instructed Self-Assembly: A Multistep Process for Potential Cancer Therapy

(2015) Jie Zhou et al.   BIOCONJUGATE CHEMISTRY

Cucurbituril-Based Molecular Recognition

(2015) Steven J. Barrow et al.   CHEMICAL REVIEWS

Cucurbiturils: from synthesis to high-affinity binding and catalysis

(2015) Khaleel I. Assaf et al.   CHEMICAL SOCIETY REVIEWS

Comprehensive Synthesis of Monohydroxy–Cucurbit[n]urils (n = 5, 6, 7, 8): High Purity and High Conversions

(2015) Mehmet M. Ayhan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cancer Cell Death Induced by the Intracellular Self-Assembly of an Enzyme-Responsive Supramolecular Gelator

(2015) Akiko Tanaka et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Controlling Cancer Cell Fate Using Localized Biocatalytic Self-Assembly of an Aromatic Carbohydrate Amphiphile

(2015) Ricardo A. Pires et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An artificial molecular pump

(2015) Chuyang Cheng et al.   Nature Nanotechnology

Continuous-wave saturation considerations for efficient xenon depolarization

(2015) Martin Kunth et al.   NMR IN BIOMEDICINE

Transient assembly of active materials fueled by a chemical reaction

(2015) J. Boekhoven et al.   SCIENCE

Identification, classification, and signal amplification capabilities of high-turnover gas binding hosts in ultra-sensitive NMR

(2015) Martin Kunth et al.   Chemical Science

Tunable solid-state fluorescent materials for supramolecular encryption

(2015) Xisen Hou et al.   Nature Communications

Self-Assemblies Based on the “Outer-Surface Interactions” of Cucurbit[n]urils: New Opportunities for Supramolecular Architectures and Materials

(2014) Xin-Long Ni et al.   ACCOUNTS OF CHEMICAL RESEARCH

Supramolecular Chemistry of p-Sulfonatocalix[n]arenes and Its Biological Applications

(2014) Dong-Sheng Guo et al.   ACCOUNTS OF CHEMICAL RESEARCH

Supramolecular Inhibition of Amyloid Fibrillation by Cucurbit[7]uril

(2014) Hong Hee Lee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fast Gradient-Encoded CEST Spectroscopy of Hyperpolarized Xenon

(2014) Jörg Döpfert et al.   CHEMPHYSCHEM

Past and Future Solid-State NMR Spectroscopy Studies at the Convergence Point between Biology and Materials Research

(2014) Gil Goobes   ISRAEL JOURNAL OF CHEMISTRY

Quantitative chemical exchange saturation transfer with hyperpolarized nuclei (qHyper-CEST): Sensing xenon-host exchange dynamics and binding affinities by NMR

(2014) M. Kunth et al.   JOURNAL OF CHEMICAL PHYSICS

Observing and preventing rubidium runaway in a direct-infusion xenon-spin hyperpolarizer optimized for high-resolution hyper-CEST (chemical exchange saturation transfer using hyperpolarized nuclei) NMR

(2014) C. Witte et al.   JOURNAL OF CHEMICAL PHYSICS

Ultrafast CEST imaging

(2014) Jörg Döpfert et al.   JOURNAL OF MAGNETIC RESONANCE

Multichannel MRI Labeling of Mammalian Cells by Switchable Nanocarriers for Hyperpolarized Xenon

(2014) Stefan Klippel et al.   NANO LETTERS

Genetically encoded reporters for hyperpolarized xenon magnetic resonance imaging

(2014) Mikhail G. Shapiro et al.   Nature Chemistry

Development of an antibody-based, modular biosensor for 129Xe NMR molecular imaging of cells at nanomolar concentrations

(2014) H. M. Rose et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The influence of equatorial substitution and K+ion concentration: an encapsulation study of CH4, CH3F, CH3Cl, CH2F2and CF4, in Q[5], CyP5Q[5] and a CyP5Q[5]-carboxylate derivative

(2014) C. Pradeep Kumar et al.   SUPRAMOLECULAR CHEMISTRY

Magic Angle Spinning NMR of Paramagnetic Proteins

(2013) Michael J. Knight et al.   ACCOUNTS OF CHEMICAL RESEARCH

Back Cover: Supramolecular Velcro for Reversible Underwater Adhesion (Angew. Chem. Int. Ed. 11/2013)

(2013) Youngjoo Ahn et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ultrafast Scanning of Exchangeable Sites by NMR Spectroscopy

(2013) Xiang Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Twisted Cucurbit[14]uril

(2013) Xiao-Jie Cheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Probing Slow Chemical Exchange at Carbonyl Sites in Proteins by Chemical Exchange Saturation Transfer NMR Spectroscopy

(2013) Pramodh Vallurupalli et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cucurbit[7]uril Containers for Targeted Delivery of Oxaliplatin to Cancer Cells

(2013) Liping Cao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Protein Structure Determination by Magic-Angle Spinning Solid-State NMR, and Insights into the Formation, Structure, and Stability of Amyloid Fibrils

(2013) Gemma Comellas et al.   Annual Review of Biophysics

Potential 129Xe-NMR biosensors based on secondary and tertiary complexes of a water-soluble pillar[5]arene derivative

(2013) Tal Adiri et al.   CHEMICAL COMMUNICATIONS

An approach to networks based on coordination of alkyl-substituted cucurbit[5]urils and potassium ions

(2013) Zhong-Fei Li et al.   CRYSTENGCOMM

Synthesis of Cucurbit[6]uril Derivatives and Insights into Their Solubility in Water

(2013) Véronique Lewin et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Slice-selective gradient-encoded CEST spectroscopy for monitoring dynamic parameters and high-throughput sample characterization

(2013) Jörg Döpfert et al.   JOURNAL OF MAGNETIC RESONANCE

Visualizing Side Chains of Invisible Protein Conformers by Solution NMR

(2013) Guillaume Bouvignies et al.   JOURNAL OF MOLECULAR BIOLOGY

Ultrafast Z-Spectroscopy for 129Xe NMR-Based Sensors

(2013) Céline Boutin et al.   Journal of Physical Chemistry Letters

Metal Ion Sensing Using Ion Chemical Exchange Saturation Transfer 19F Magnetic Resonance Imaging

(2013) Amnon Bar-Shir et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A CatalyCEST MRI Contrast Agent That Detects the Enzyme-Catalyzed Creation of a Covalent Bond

(2013) Dina V. Hingorani et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

In Vivo Targeting of Hydrogen Peroxide by Activatable Cell-Penetrating Peptides

(2013) Roy Weinstain et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The role of iron and reactive oxygen species in cell death

(2013) Scott J Dixon et al.   Nature Chemical Biology

Chemistry inside molecular containers in the gas phase

(2013) Tung-Chun Lee et al.   Nature Chemistry

NMR paves the way for atomic level descriptions of sparsely populated, transiently formed biomolecular conformers

(2013) A. Sekhar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Near-unity nuclear polarization with an open-source 129Xe hyperpolarizer for NMR and MRI

(2013) P. Nikolaou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantitative Emergence of Hetero[4]rotaxanes by Template-Directed Click Chemistry

(2012) Chenfeng Ke et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Optimized Use of Reversible Binding for Fast and Selective NMR Localization of Caged Xenon

(2012) Martin Kunth et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The preferential targeting of the diseased microvasculature by disk-like particles

(2012) Giulia Adriani et al.   BIOMATERIALS

Monofunctionalised cucurbit[6]uril synthesis using imidazolium host–guest complexation

(2012) Nan Zhao et al.   CHEMICAL COMMUNICATIONS

Supramolecular Tandem Enzyme Assays

(2012) Roy N. Dsouza et al.   CHEMISTRY-A EUROPEAN JOURNAL

Analytical solution for the depolarization of hyperpolarized nuclei by chemical exchange saturation transfer between free and encapsulated xenon (HyperCEST)

(2012) Moritz Zaiss et al.   JOURNAL OF CHEMICAL PHYSICS

Studying “Invisible” Excited Protein States in Slow Exchange with a Major State Conformation

(2012) Pramodh Vallurupalli et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis and Self-Assembly Processes of Monofunctionalized Cucurbit[7]uril

(2012) Brittany Vinciguerra et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Daisy Chain Assembly Formed from a Cucurbit[6]uril Derivative

(2012) Liping Cao et al.   ORGANIC LETTERS

Structure and backbone dynamics of a microcrystalline metalloprotein by solid-state NMR

(2012) M. J. Knight et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Design and Assembly of Rotaxane-Based Molecular Switches and Machines

(2012) Wenlong Yang et al.   Small

Solid-state nuclear magnetic resonance structural studies of proteins using paramagnetic probes

(2012) Christopher P. Jaroniec   SOLID STATE NUCLEAR MAGNETIC RESONANCE

Imaging enzyme-triggered self-assembly of small molecules inside live cells

(2012) Yuan Gao et al.   Nature Communications

Solid-State NMR Studies of Amyloid Fibril Structure

(2011) Robert Tycko   Annual Review of Physical Chemistry

Cancer cells metabolically "fertilize" the tumor microenvironment with hydrogen peroxide, driving the Warburg effect

(2011) Ubaldo E. Martinez-Outschoorn et al.   CELL CYCLE

Interaction of Xenon with Cucurbit[5]uril in Water

(2011) Gaspard Huber et al.   CHEMPHYSCHEM

Encapsulation of Drug Molecules by Cucurbiturils: Effects on their Chemical Properties in Aqueous Solution

(2011) Donal H. Macartney   ISRAEL JOURNAL OF CHEMISTRY

Deep Inside Cucurbiturils: Physical Properties and Volumes of their Inner Cavity Determine the Hydrophobic Driving Force for Host-Guest Complexation

(2011) Werner M. Nau et al.   ISRAEL JOURNAL OF CHEMISTRY

Locating the Cyclopentano Cousins of the Cucurbit[n]uril Family

(2011) Feng Wu et al.   JOURNAL OF ORGANIC CHEMISTRY

Templated Synthesis of Glycoluril Hexamer and Monofunctionalized Cucurbit[6]uril Derivatives

(2011) Derick Lucas et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Determining Protease Substrate Selectivity and Inhibition by Label-Free Supramolecular Tandem Enzyme Assays

(2011) Garima Ghale et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Molecular Recognition of Insulin by a Synthetic Receptor

(2011) Jordan M. Chinai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Operational calixarene-based fluorescent sensing systems for choline and acetylcholine and their application to enzymatic reactions

(2011) Dong-Sheng Guo et al.   Chemical Science

Cucurbituril chemistry: a tale of supramolecular success

(2011) Eric Masson et al.   RSC Advances

Competitive Inhibition at the Glycine Site of the N-Methyl-d-Aspartate Receptor Mediates Xenon Neuroprotection against Hypoxia–Ischemia

(2010) Paul Banks et al.   ANESTHESIOLOGY

A self-calibrating PARACEST MRI contrast agent that detects esterase enzyme activity

(2010) Yuguo Li et al.   Contrast Media & Molecular Imaging

Implementation of anion-receptor macrocycles in supramolecular tandem assays for enzymes involving nucleotides as substrates, products, and cofactors

(2010) Mara Florea et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Toxicity of cucurbit[7]uril and cucurbit[8]uril: an exploratory in vitro and in vivo study

(2010) Vanya D. Uzunova et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Toxicology and Drug Delivery by Cucurbit[n]uril Type Molecular Containers

(2010) Gaya Hettiarachchi et al.   PLoS One

Substrate-Selective Supramolecular Tandem Assays: Monitoring Enzyme Inhibition of Arginase and Diamine Oxidase by Fluorescent Dye Displacement from Calixarene and Cucurbituril Macrocycles

(2009) Werner M. Nau et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cryptophane Xenon-129 Nuclear Magnetic Resonance Biosensors Targeting Human Carbonic Anhydrase

(2009) Jennifer M. Chambers et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish

(2009) Philipp Niethammer et al.   NATURE

Actin, a Central Player in Cell Shape and Movement

(2009) T. D. Pollard et al.   SCIENCE

Enzymatic Hydrogelation of Small Molecules

(2008) Zhimou Yang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Molecular Self-Assembly into One-Dimensional Nanostructures

(2008) Liam C. Palmer et al.   ACCOUNTS OF CHEMICAL RESEARCH

Single-crystal to single-crystal phase transition of cucurbit[5]uril hydrochloride hydrates: large water-filled channels transforming to layers of unusual stability

(2008) David Bardelang et al.   CHEMICAL COMMUNICATIONS

Water soluble cucurbit[6]uril derivative as a potential Xe carrier for 129Xe NMR-based biosensors

(2008) Byoung Soo Kim et al.   CHEMICAL COMMUNICATIONS

Cucurbit[n]urils: from mechanism to structure and function

(2008) Lyle Isaacs   CHEMICAL COMMUNICATIONS

Supramolecular Tandem Enzyme Assays for Multiparameter Sensor Arrays and Enantiomeric Excess Determination of Amino Acids

(2008) David M. Bailey et al.   CHEMISTRY-A EUROPEAN JOURNAL

Electronic Structure, Molecular Electrostatic Potential, and NMR Chemical Shifts in Cucurbit[n]urils (n= 5−8), Ferrocene, and Their Complexes

(2008) Rahul V. Pinjari et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Cucurbit[n]uril Formation Proceeds by Step-Growth Cyclo-oligomerization

(2008) Wei-Hao Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Using Enantioselective Indicator Displacement Assays To Determine the Enantiomeric Excess of α-Amino Acids

(2008) Diana Leung et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Integrative Self-Sorting: Construction of a Cascade-Stoppered Hetero[3]rotaxane

(2008) Wei Jiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Carbonic anhydrases: novel therapeutic applications for inhibitors and activators

(2008) Claudiu T. Supuran   NATURE REVIEWS DRUG DISCOVERY

Biosensing using laser-polarized xenon NMR/MRI

(2008) Patrick Berthault et al.   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY