Cucurbitacin E Inhibits Huh7 Hepatoma Carcinoma Cell Proliferation and Metastasis via Suppressing MAPKs and JAK/STAT3 Pathways

Cancer statistics, 2019

(2019) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

PG490-88, a derivative of triptolide, suppresses ischemia/reperfusion-induced lung damage by maintaining tight junction barriers and targeting multiple signaling pathways

(2019) Hsin-Ping Pao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Network-pharmacology-based identification of caveolin-1 as a key target of Oldenlandia diffusa to suppress breast cancer metastasis

(2019) Bowen Yang et al.   BIOMEDICINE & PHARMACOTHERAPY

Transcriptomic analyses reveal the molecular mechanisms of schisandrin B alleviates CCl4-induced liver fibrosis in rats by RNA-sequencing

(2019) Hai Zhang et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Mining Conditions Specific Hub Genes from RNA-Seq Gene Expression Data via Biclustering and its Application to Drug Discovery

(2019) ANKUSH MAIND et al.   IET Systems Biology

Norcantharidin Suppresses YD-15 Cell Invasion Through Inhibition of FAK/Paxillin and F-Actin Reorganization

(2019) Kyoung-Ok Hong et al.   MOLECULES

Piperlongumine Induces Apoptosis and Synergizes with Doxorubicin by Inhibiting the JAK2-STAT3 Pathway in Triple-Negative Breast Cancer

(2019) Di Chen et al.   MOLECULES

Clinical efficacy of combination of pertuzumab, trastuzumab, and docetaxel for treatment of patients with HER2-positive breast cancer

(2019) Yan-cui Liu et al.   MEDICINE

In Vitro and In Vivo Antitumor Activity of Cucurbitacin C, a Novel Natural Product From Cucumber

(2019) Dinglan Wu et al.   Frontiers in Pharmacology

Natural compounds and combination therapy in colorectal cancer treatment

(2018) A. Rejhová et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Hepatocellular carcinoma

(2018) Alejandro Forner et al.   LANCET

Targeting ERK, an Achilles' Heel of the MAPK pathway, in cancer therapy

(2018) Feifei Liu et al.   Acta Pharmaceutica Sinica B

Structure-based virtual screening for the identification of high affinity small molecule towards STAT3 for the clinical treatment of Osteosarcoma

(2018) Ravina Khandelwal et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Correlation of ERK/MAPK signaling pathway with proliferation and apoptosis of colon cancer cells

(2018) Gang Zhou et al.   Oncology Letters

From diagnosis to treatment of hepatocellular carcinoma: An epidemic problem for both developed and developing world

(2017) Dimitrios Dimitroulis et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Low-Dose Paclitaxel Inhibits Tumor Cell Growth by Regulating Glutaminolysis in Colorectal Carcinoma Cells

(2017) Chaoxiang Lv et al.   Frontiers in Pharmacology

Cucurbitacin E inhibits osteosarcoma cells proliferation and invasion through attenuation of PI3K/AKT/mTOR signalling pathway

(2016) Y. Wang et al.   BIOSCIENCE REPORTS

Negative feedback regulation of the ERK1/2 MAPK pathway

(2016) David Lake et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Cucurbitacin E Potently Modulates the Activity of Encephalitogenic Cells

(2016) Bojan Jevtić et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Therapeutic control and resistance of the EGFR-driven signaling network in glioblastoma

(2015) Francisco Azuaje et al.   Cell Communication and Signaling

Targeting Apoptosis and Multiple Signaling Pathways with Icariside II in Cancer Cells

(2015) Muhammad Khan et al.   International Journal of Biological Sciences

Pleiotropic Role of Dietary Phytochemicals in Cancer: Emerging Perspectives for Combinational Therapy

(2015) Sivanantham Banudevi et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Therapeutic ROS targeting of GADD45γ in the induction of G2/M arrest in primary human colorectal cancer cell lines by cucurbitacin E

(2014) Y-C Hsu et al.   Cell Death & Disease

Cucurbitacin E exhibits anti-inflammatory effect in RAW 264.7 cells via suppression of NF-κB nuclear translocation

(2013) Jing Qiao et al.   INFLAMMATION RESEARCH

Cucurbitacin E as Inducer of Cell Death and Apoptosis in Human Oral Squamous Cell Carcinoma Cell Line SAS

(2013) Chao-Ming Hung et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cucurbitacins as Inducers of Cell Death and a Rich Source of Potential Anticancer Compounds

(2012)   CURRENT PHARMACEUTICAL DESIGN

Microvascular Invasion Is a Better Predictor of Tumor Recurrence and Overall Survival Following Surgical Resection for Hepatocellular Carcinoma Compared to the Milan Criteria

(2011) Kheng-Choon Lim et al.   ANNALS OF SURGERY

Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90

(2011) Kamalika Moulick et al.   Nature Chemical Biology