Mammalian egg coat modifications and the block to polyspermy

Structure of mammalian plasma fetuin-B and its mechanism of selective metallopeptidase inhibition

(2019) Anna Cuppari et al.   IUCrJ

Mammalian plasma fetuin-B is a selective inhibitor of ovastacin and meprin metalloproteinases

(2019) Konstantin Karmilin et al.   Scientific Reports

Anchoring cortical granules in the cortex ensures trafficking to the plasma membrane for post-fertilization exocytosis

(2019) Edgar-John Vogt et al.   Nature Communications

Molecular basis of egg coat cross-linking sheds light on ZP1-associated female infertility

(2019) Kaoru Nishimura et al.   Nature Communications

Glycan-Independent Gamete Recognition Triggers Egg Zinc Sparks and ZP2 Cleavage to Prevent Polyspermy

(2018) Keizo Tokuhiro et al.   DEVELOPMENTAL CELL

Zinc sparks induce physiochemical changes in the egg zona pellucida that prevent polyspermy

(2017) Emily L. Que et al.   Integrative Biology

Intracellular activation of ovastacin mediates pre-fertilization hardening of the zona pellucida

(2017) Hagen Körschgen et al.   MOLECULAR HUMAN REPRODUCTION

Cell and genetic predictors of human blastocyst hatching success in assisted reproduction

(2017) Anastasiya G. Syrkasheva et al.   ZYGOTE

A Unique Egg Cortical Granule Localization Motif Is Required for Ovastacin Sequestration to Prevent Premature ZP2 Cleavage and Ensure Female Fertility in Mice

(2017) Bo Xiong et al.   PLoS Genetics

SAS1B Is an Egg Specific High Affinity Oolemmal Binding Partner for Sperm Specific Acrosomal SLLP1 During Fertilization.

(2017) Arabinda Mandal et al.   BIOLOGY OF REPRODUCTION

Mouse sperm begin to undergo acrosomal exocytosis in the upper isthmus of the oviduct

(2016) Florenza A. La Spina et al.   DEVELOPMENTAL BIOLOGY

Association of high fetuin-B concentrations in serum with fertilization rate in IVF: a cross-sectional pilot study

(2016) Julia Floehr et al.   HUMAN REPRODUCTION

Down-regulation of the liver-derived plasma protein fetuin-B mediates reversible female infertility

(2016) J. Floehr et al.   MOLECULAR HUMAN REPRODUCTION

Recombinant fetuin-B protein maintains high fertilization rate in cumulus cell-free mouse oocytes

(2016) E. Dietzel et al.   MOLECULAR HUMAN REPRODUCTION

A structured interdomain linker directs self-polymerization of human uromodulin

(2016) Marcel Bokhove et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The fertilization-induced zinc spark is a novel biomarker of mouse embryo quality and early development

(2016) Nan Zhang et al.   Scientific Reports

The zinc spark is an inorganic signature of human egg activation

(2016) Francesca E. Duncan et al.   Scientific Reports

The C-terminal region of OVGP1 remodels the zona pellucida and modifies fertility parameters

(2016) B. Algarra et al.   Scientific Reports

Oviductal estrogen receptor α signaling prevents protease-mediated embryo death

(2015) Wipawee Winuthayanon et al.   eLife

Glycosylated Chicken ZP2 Accumulates in the Egg Coat of Immature Oocytes and Remains Localized to the Germinal Disc Region of Mature Eggs1

(2014) Shunsuke Nishio et al.   BIOLOGY OF REPRODUCTION

A single domain of the ZP2 zona pellucida protein mediates gamete recognition in mice and humans

(2014) Matteo A. Avella et al.   JOURNAL OF CELL BIOLOGY

Juno is the egg Izumo receptor and is essential for mammalian fertilization

(2014) Enrica Bianchi et al.   NATURE

Quantitative mapping of zinc fluxes in the mammalian egg reveals the origin of fertilization-induced zinc sparks

(2014) Emily L. Que et al.   Nature Chemistry

Mutant ZP1 in Familial Infertility

(2014) Hua-Lin Huang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Fetuin-B, a Liver-Derived Plasma Protein Is Essential for Fertilization

(2013) Eileen Dietzel et al.   DEVELOPMENTAL CELL

An oocyte-specific astacin family protease, alveolin, is released from cortical granules to trigger egg envelope hardening during fertilization in medaka (Oryzias latipes)

(2012) Yasushi Shibata et al.   DEVELOPMENTAL BIOLOGY

Human sperm bind to the N-terminal domain of ZP2 in humanized zonae pellucidae in transgenic mice

(2012) Boris Baibakov et al.   JOURNAL OF CELL BIOLOGY

Ovastacin, a cortical granule protease, cleaves ZP2 in the zona pellucida to prevent polyspermy

(2012) Anna D. Burkart et al.   JOURNAL OF CELL BIOLOGY

Zinc Sparks Are Triggered by Fertilization and Facilitate Cell Cycle Resumption in Mammalian Eggs

(2011) Alison M. Kim et al.   ACS Chemical Biology

A Structural View of Egg Coat Architecture and Function in Fertilization1

(2011) Magnus Monné et al.   BIOLOGY OF REPRODUCTION

Oocyte specific oolemmal SAS1B involved in sperm binding through intra-acrosomal SLLP1 during fertilization

(2011) Monika Sachdev et al.   DEVELOPMENTAL BIOLOGY

ZP2 and ZP3 cytoplasmic tails prevent premature interactions and ensure incorporation into the zona pellucida

(2011) M. Jimenez-Movilla et al.   JOURNAL OF CELL SCIENCE

Most fertilizing mouse spermatozoa begin their acrosome reaction before contact with the zona pellucida during in vitro fertilization

(2011) M. Jin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The biology and dynamics of mammalian cortical granules

(2011) Min Liu   Reproductive Biology and Endocrinology

Human Sperm Binding Is Mediated by the Sialyl-Lewisx Oligosaccharide on the Zona Pellucida

(2011) P.-C. Pang et al.   SCIENCE

Involvement of selectin-like carbohydrate binding specificity in human gamete interaction

(2010) S. Oehninger et al.   ANDROLOGIA

Insights into Egg Coat Assembly and Egg-Sperm Interaction from the X-Ray Structure of Full-Length ZP3

(2010) Ling Han et al.   CELL

In humans, zona pellucida glycoprotein-1 binds to spermatozoa and induces acrosomal exocytosis

(2010) Anasua Ganguly et al.   HUMAN REPRODUCTION

Zinc availability regulates exit from meiosis in maturing mammalian oocytes

(2010) Alison M Kim et al.   Nature Chemical Biology

A trefoil domain in the major rabbit zona pellucida protein

(2010) Peer Bork   PROTEIN SCIENCE

Gamete Recognition in Mice Depends on the Cleavage Status of an Egg's Zona Pellucida Protein

(2010) G. Gahlay et al.   SCIENCE

Mechanisms of Sperm-Egg Interactions: Between Sugars and Broken Bonds

(2010) P. E. Visconti et al.   Science Signaling

Mechanical properties of zona pellucida hardening

(2009) Massimiliano Papi et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Structural changes of the zona pellucida during fertilization and embryo development

(2008) Giuseppe Familiari   Frontiers in Bioscience-Landmark

Native human zona pellucida glycoproteins: purification and binding properties

(2008) P. C.N. Chiu et al.   HUMAN REPRODUCTION

Crystal structure of the ZP-N domain of ZP3 reveals the core fold of animal egg coats

(2008) Magnus Monné et al.   NATURE

Oviduct-specific glycoprotein and heparin modulate sperm-zona pellucida interaction during fertilization and contribute to the control of polyspermy

(2008) P. Coy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phylogenetic Analysis and Identification of Pseudogenes Reveal a Progressive Loss of Zona Pellucida Genes During Evolution of Vertebrates1

(2007) Ghylène Goudet et al.   BIOLOGY OF REPRODUCTION