Leveraging genome-wide data to investigate differences between opioid use vs. opioid dependence in 41,176 individuals from the Psychiatric Genomics Consortium

Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use

(2019) Mengzhen Liu et al.   NATURE GENETICS

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

(2019) Richard Karlsson Linnér et al.   NATURE GENETICS

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions

(2019) David M. Howard et al.   NATURE NEUROSCIENCE

Identification of common genetic risk variants for autism spectrum disorder

(2019) Jakob Grove et al.   NATURE GENETICS

The Missing Diversity in Human Genetic Studies

(2019) Giorgio Sirugo et al.   CELL

Defining the Genetic, Genomic, Cellular, and Diagnostic Architectures of Psychiatric Disorders

(2019) Patrick F. Sullivan et al.   CELL

Genome‐wide association studies of alcohol dependence, DSM‐IV criterion count, and individual criteria

(2019) Dongbing Lai et al.   GENES BRAIN AND BEHAVIOR

Management of acute musculoskeletal pain (excluding low back pain): protocol for a systematic review and network meta-analysis of randomised trials

(2019) Jason W Busse et al.   BMJ Open

Genome-wide association study of post-traumatic stress disorder reexperiencing symptoms in >165,000 US veterans

(2019) Joel Gelernter et al.   NATURE NEUROSCIENCE

Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations

(2019) Henry R. Kranzler et al.   Nature Communications

A global overview of pleiotropy and genetic architecture in complex traits

(2019) Kyoko Watanabe et al.   NATURE GENETICS

Psychiatric Genomics: An Update and an Agenda

(2018) Patrick F. Sullivan et al.   AMERICAN JOURNAL OF PSYCHIATRY

Genome-wide Association Study Identifies a Regulatory Variant of RGMA Associated With Opioid Dependence in European Americans

(2018) Zhongshan Cheng et al.   BIOLOGICAL PSYCHIATRY

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

(2018) Naomi R. Wray et al.   NATURE GENETICS

Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways

(2018) Mats Nagel et al.   NATURE GENETICS

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

(2018) James J. Lee et al.   NATURE GENETICS

Real-life helping behaviours in North America: A genome-wide association approach

(2018) Georg Primes et al.   PLoS One

GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal influence of schizophrenia

(2018) Joëlle A. Pasman et al.   NATURE NEUROSCIENCE

Leveraging Polygenic Functional Enrichment to Improve GWAS Power

(2018) Gleb Kichaev et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts

(2018) Sandra Sanchez-Roige et al.   AMERICAN JOURNAL OF PSYCHIATRY

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

(2018) Raymond K. Walters et al.   NATURE NEUROSCIENCE

Identification of CDC42BPG as a novel susceptibility locus for hyperuricemia in a Japanese population

(2017) Yoshiki Yasukochi et al.   MOLECULAR GENETICS AND GENOMICS

Genetic effects on gene expression across human tissues

(2017) François Aguet et al.   NATURE

Functional mapping and annotation of genetic associations with FUMA

(2017) Kyoko Watanabe et al.   Nature Communications

Power estimation and sample size determination for replication studies of genome-wide association studies

(2016) Wei Jiang et al.   BMC GENOMICS

Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation

(2016) Thomas J Hoffmann et al.   NATURE GENETICS

Nonmedical Prescription-Opioid Use and Heroin Use

(2016)   NEW ENGLAND JOURNAL OF MEDICINE

The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog)

(2016) Jacqueline MacArthur et al.   NUCLEIC ACIDS RESEARCH

Increases in Drug and Opioid Overdose Deaths — United States, 2000–2014

(2016) Rose A. Rudd et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Genome-Wide Association of Heroin Dependence in Han Chinese

(2016) Gursharan Kalsi et al.   PLoS One

Evidence of CNIH3 involvement in opioid dependence

(2015) E C Nelson et al.   MOLECULAR PSYCHIATRY

A global reference for human genetic variation

(2015) Richard A. Gibbs et al.   NATURE

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

(2015) Brendan K Bulik-Sullivan et al.   NATURE GENETICS

MAGMA: Generalized Gene-Set Analysis of GWAS Data

(2015) Christiaan A. de Leeuw et al.   PLoS Computational Biology

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

(2015) Cathie Sudlow et al.   PLOS MEDICINE

PRSice: Polygenic Risk Score software

(2014) Jack Euesden et al.   BIOINFORMATICS

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

Genetic variability in the regulation of gene expression in ten regions of the human brain

(2014) Adaikalavan Ramasamy et al.   NATURE NEUROSCIENCE

Medication-Assisted Therapies — Tackling the Opioid-Overdose Epidemic

(2014) Nora D. Volkow et al.   NEW ENGLAND JOURNAL OF MEDICINE

A General Approach for Haplotype Phasing across the Full Spectrum of Relatedness

(2014) Jared O'Connell et al.   PLoS Genetics

Genome-Wide Association Study of Opioid Dependence: Multiple Associations Mapped to Calcium and Potassium Pathways

(2013) Joel Gelernter et al.   BIOLOGICAL PSYCHIATRY

Effectively Identifying eQTLs from Multiple Tissues by Combining Mixed Model and Meta-analytic Approaches

(2013) Jae Hoon Sul et al.   PLoS Genetics

Treatment of substance abusing patients with comorbid psychiatric disorders

(2011) Thomas M. Kelly et al.   ADDICTIVE BEHAVIORS

Molecular signatures database (MSigDB) 3.0

(2011) A. Liberzon et al.   BIOINFORMATICS

METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS

Integrating common and rare genetic variation in diverse human populations

(2010)   NATURE

A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

(2009) Bryan N. Howie et al.   PLoS Genetics