SIRT1 protects against aortic dissection by regulating AP-1/decorin signaling-mediated PDCD4 activation

Chlorpyrifos activates cell pyroptosis and increases susceptibility on oxidative stress-induced toxicity by miR-181/SIRT1/PGC-1α/Nrf2 signaling pathway in human neuroblastoma SH-SY5Y cells: Implication for association between chlorpyrifos and Parkinson's

(2019) Meng-Wen Zhao et al.   ENVIRONMENTAL TOXICOLOGY

MicroRNA-21 Knockout Exacerbates Angiotensin II–Induced Thoracic Aortic Aneurysm and Dissection in Mice With Abnormal Transforming Growth Factor-β–SMAD3 SignalingHighlights

(2018) Xiaofan Huang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Gefäßnotfälle im Notarztdienst – Teil 2: rupturiertes Bauchaortenaneurysma und akute Aortendissektion

(2018) Tino Beck et al.   Notarzt

Glucocorticoids Regulate the Vascular Remodeling of Aortic Dissection Via the p38 MAPK-HSP27 Pathway Mediated by Soluble TNF-RII

(2018) Lei Zhang et al.   EBioMedicine

Upregulation of miR-181 Decreases c-Fos and SIRT-1 in the Hippocampus of 3xTg-AD Mice

(2018) Carlos J. Rodriguez-Ortiz et al.   JOURNAL OF ALZHEIMERS DISEASE

Licochalcone A attenuates abdominal aortic aneurysm induced by angiotensin II via regulating the miR-181b/SIRT1/HO-1 signaling

(2018) Xuhui Hou et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Gene expression profiling of acute type A aortic dissection combined with in vitro assessment†

(2017) Naoyuki Kimura et al.   EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY

miR-181b regulates vascular stiffness age dependently in part by regulating TGF-β signaling

(2017) Daijiro Hori et al.   PLoS One

Resveratrol Inhibits Aortic Root Dilatation in the Fbn1C1039G/+Marfan Mouse ModelHighlights

(2016) Stijntje Hibender et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Celastrol-Induced Suppression of the MiR-21/ERK Signalling Pathway Attenuates Cardiac Fibrosis and Dysfunction

(2016) Mian Cheng et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Vascular Smooth Muscle Sirtuin-1 Protects Against Diet-Induced Aortic StiffnessNovelty and Significance

(2016) Jessica L. Fry et al.   HYPERTENSION

miR-181b functions as an oncomiR in colorectal cancer by targeting PDCD4

(2016) Yanqing Liu et al.   Protein & Cell

β-Aminopropionitrile monofumarate induces thoracic aortic dissection in C57BL/6 mice

(2016) Weihong Ren et al.   Scientific Reports

Sirtuin 1 Is a Negative Regulator of Parathyroid Hormone Stimulation of Matrix Metalloproteinase 13 Expression in Osteoblastic Cells

(2015) Yurong Fei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Management of acute aortic dissection

(2015) Christoph A Nienaber et al.   LANCET

Possible Dual Role of Decorin in Abdominal Aortic Aneurysm

(2015) Koshiro Ueda et al.   PLoS One

Decorin and biglycan retain LDL in disease-prone valvular and aortic subendothelial intimal matrix

(2014) Edward B. Neufeld et al.   ATHEROSCLEROSIS

2014 ESC Guidelines on the diagnosis and treatment of aortic diseases

(2014)   EUROPEAN HEART JOURNAL

Comparative tissue proteomics analysis of thoracic aortic dissection with hypertension using the iTRAQ technique

(2014) Kefeng Zhang et al.   EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY

Population-Based Study of Incidence and Outcome of Acute Aortic Dissection and Premorbid Risk Factor Control

(2013) Dominic P.J. Howard et al.   CIRCULATION

Biological interplay between proteoglycans and their innate immune receptors in inflammation

(2013) Helena Frey et al.   FEBS Journal

Overexpression of SIRT1 in vascular smooth muscle cells attenuates angiotensin II-induced vascular remodeling and hypertension in mice

(2013) Peng Gao et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Molecular mechanisms of thoracic aortic dissection

(2013) Darrell Wu et al.   JOURNAL OF SURGICAL RESEARCH

Decorin

(2012) Thomas Neill et al.   AMERICAN JOURNAL OF PATHOLOGY

Vascular Smooth Muscle Cell Sirtuin 1 Protects Against DNA Damage and Inhibits Atherosclerosis

(2012) Isabelle Gorenne et al.   CIRCULATION

AP-1 Mediated Transcriptional Repression of Matrix Metalloproteinase-9 by Recruitment of Histone Deacetylase 1 in Response to Interferon β

(2012) Megan L. Mittelstadt et al.   PLoS One

Mechanical Stretch Modulates MicroRNA 21 Expression, Participating in Proliferation and Apoptosis in Cultured Human Aortic Smooth Muscle Cells

(2012) Jian tao Song et al.   PLoS One

MicroRNA-21 Blocks Abdominal Aortic Aneurysm Development and Nicotine-Augmented Expansion

(2012) L. Maegdefessel et al.   Science Translational Medicine

Sirtuin 1 Retards Hyperphosphatemia-Induced Calcification of Vascular Smooth Muscle Cells

(2011) Aya Takemura et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

SIRT1 Acts as a Modulator of Neointima Formation Following Vascular Injury in Mice

(2011) Li Li et al.   CIRCULATION RESEARCH

Signaling by the Matrix Proteoglycan Decorin Controls Inflammation and Cancer Through PDCD4 and MicroRNA-21

(2011) R. Merline et al.   Science Signaling

Serpina3n attenuates granzyme B-mediated decorin cleavage and rupture in a murine model of aortic aneurysm

(2011) L S Ang et al.   Cell Death & Disease

Proteoglycans in health and disease: novel regulatory signaling mechanisms evoked by the small leucine-rich proteoglycans

(2010) Renato V. Iozzo et al.   FEBS Journal

SIRT1 markedly extends replicative lifespan if the NAD+salvage pathway is enhanced

(2009) Cynthia Ho et al.   FEBS LETTERS

Recent progress in the biology and physiology of sirtuins

(2009) Toren Finkel et al.   NATURE

Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21

(2009) Frederick J Sheedy et al.   NATURE IMMUNOLOGY

Interactions between SIRT1 and AP-1 reveal a mechanistic insight into the growth promoting properties of alumina (Al2O3) nanoparticles in mouse skin epithelial cells

(2008) S. Dey et al.   CARCINOGENESIS

SirT1 Gain of Function Increases Energy Efficiency and Prevents Diabetes in Mice

(2008) Alexander S. Banks et al.   Cell Metabolism