Review
Genetics & Heredity
Katy Vandereyken, Alejandro Sifrim, Bernard Thienpont, Thierry Voet
Summary: The joint analysis of multiple molecular modalities from single cells, such as the genome, epigenome, transcriptome, proteome, and metabolome, is transforming our understanding of cell biology in health and disease. This review discusses the advances in single-cell and spatial multi-omics technologies and the computational strategies for integrating information across these molecular layers. It also highlights their impact on fundamental cell biology and translational research, current challenges, and future prospects.
NATURE REVIEWS GENETICS
(2023)
Article
Ecology
Atte Moilanen, Pauli Lehtinen, Ilmari Kohonen, Joel Jalkanen, Elina A. Virtanen, Heini Kujala
Summary: Spatial (conservation) prioritization integrates data on biodiversity, costs, and threats to create spatial priority maps for ecologically informed land use planning. This article describes novel methods that enhance the utility of spatial priority ranking in large-scale analyses and interactive planning.
METHODS IN ECOLOGY AND EVOLUTION
(2022)
Article
Ecology
Ellen C. Martin, Brage Bremset Hansen, Aline Magdalena Lee, Ivar Herfindal
Summary: Spatial population synchrony is common and important for predicting extinction risk. The extent of synchrony can be explained by environmental conditions and species sensitivity to the environment. Populations that are closer together experience more similar fluctuations in their environments and are therefore more synchronized.
JOURNAL OF ANIMAL ECOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Yann X. C. Bourgeois, Ben H. Warren
Summary: The continuous improvement of high-throughput sequencing techniques has enabled the production of whole genome data in various species, which in turn provides better tools for integrating selection into historical frameworks. However, the plethora of analytical tools may confuse users and hinder the dissemination of the latest methods.
Article
Ecology
Ellen C. Martin, Brage Bremset Hansen, Ivar Herfindal, Aline Magdalena Lee
Summary: Spatially synchronized population dynamics are common in nature and understanding their causes is crucial for species persistence. However, for migratory species, the degree of spatial autocorrelation in the environment may change across seasons and vary by their geographic location along the migratory route or on a nonbreeding ground, complicating the synchronizing effect of the environment.
Article
Economics
Rodrigo Garcia Arancibia, Pamela Llop, Mariel Lovatto
Summary: We present five nonparametric kriging-type predictors for spatial data without covariates. These methods aim to fully utilize the information from spatial proximity and similarity among neighborhoods of the variable of interest through different combinations of kernels (one or two kernels) and distances (multiplicative and additive). Simulation studies and housing price predictions demonstrate the good performance of the proposed methods.
PAPERS IN REGIONAL SCIENCE
(2023)
Review
Chemistry, Multidisciplinary
David Goyard, Angela Martin-Serrano Ortiz, Didier Boturyn, Olivier Renaudet
Summary: This review summarizes the synthetic strategies of using click chemistry to decorate synthetic multivalent scaffolds with glycans. It discusses the potential of multiple copies of glycans conjugated to cyclopeptide scaffolds (multivalent glycocyclopeptides) to interact with carbohydrate binding proteins and stimulate immunity against tumor cells.
CHEMICAL SOCIETY REVIEWS
(2022)
Article
Plant Sciences
Min-Xin Luo, Hsin-Pei Lu, Min-Wei Chai, Jui-Tse Chang, Pei-Chun Liao
Summary: The study found that in Taiwan, populations of A. caudatifolium have shifted upward and northward, while its close relative A. morrisonense has expanded downward. Northern populations of A. caudatifolium have diverse chlorotypes and high genetic diversity, but gene flow between north and south is obstructed by topography, geographic distance, and climate heterogeneities.
Editorial Material
Biochemical Research Methods
Shaina Lu, Daniel Furth, Jesse Gillis
Summary: Computational methods employ various integrative strategies to address the challenges of spatially resolved transcriptomics data analysis.
Article
Materials Science, Multidisciplinary
Jose A. F. O. Correia, Shun-Peng Zhu, Filippo Berto
Summary: Current research employs a mechanism-based approach to study fatigue performance of advanced materials. This special issue consists of 27 research articles that cover various topics including additive manufacturing, microstructure effects, probabilistic modeling, and fatigue approaches. The research aims to guide further improvement and application of new materials in engineering.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2023)
Article
Computer Science, Artificial Intelligence
Yunqi Li, Hanxiong Chen, Shuyuan Xu, Yingqiang Ge, Juntao Tan, Shuchang Liu, Yongfeng Zhang
Summary: This survey provides a systematic overview of existing works on fairness in recommendation, introducing fundamental concepts of fairness and presenting methods and challenges in considering fairness in recommender systems.
ACM TRANSACTIONS ON INTELLIGENT SYSTEMS AND TECHNOLOGY
(2023)
Article
Economics
Alois Humer, Rodrigo Cardoso, Evert Meijers
Summary: This paper criticizes traditional models of urban-regional expansion and reconceptualizes the relations between cores and rings. By analyzing local population data in functional urban regions in Finland, Austria, and the Netherlands, the results show a 'break of the cycle' in polycentric regions and a shift towards a new period, which is termed 'syncurbanization'.
Review
Ecology
Stefano Palmero, Joe Premier, Stephanie Kramer-Schadt, Pedro Monterroso, Marco Heurich
Summary: Robust monitoring is crucial for successful conservation planning, especially for elusive and low-density species like felids. This study examined the impact of sampling designs on the precision of population density estimates for territorial felids. Analysis of 137 camera-trapping and spatial capture-recapture studies revealed that the number of individuals captured, recapture frequency, and capture probability are the most important variables affecting precision. Guidelines for future studies and a reporting protocol were provided to improve the reproducibility and comparability of spatial capture-recapture research.
Article
Clinical Neurology
Yifan Yang, Bangyue Wang, Xinbo Ge, Wenpeng Lu, Chao Peng, Yan Zhao, Jian Li, Jinghua Wang, Ping Lei, Jianning Zhang, Lei Feng, Zhenbo Liu, Xinyu Yang
Summary: This study aimed to determine the mortality rate and predictors of mortality in Chinese patients with untreated ruptured intracranial aneurysms. The study found that approximately 58.6% of patients with ruptured intracranial aneurysms died within 1 month of symptom onset, and 68.1% died within 2 years. Hunt and Hess grades 3 to 5, loss of consciousness at symptom onset, and aneurysm size ≥5 mm were identified as predictors of mortality during the 2-year follow-up. The study also highlighted a significant number of patients refusing surgical treatment.
Article
Multidisciplinary Sciences
Yan Zhou, Jose Russo, Jose Rueff, Marcelo A. M. Pires, Guilherme Bezerra de Castro
Summary: Population study reveals that Xavante Indians have distinct genetic compositions and extremely low risk of breast cancer, providing new insights for breast cancer research.
SCIENTIFIC REPORTS
(2023)
Article
Geography, Physical
Hamidreza Rabiei-Dastjerdi, Gavin McArdle, Stephen A. Matthews, Peter Keenan
Summary: Searching for a property involves making a decision based on household needs, building facilities, and location characteristics. Despite the availability of digital earth data, real-estate websites are found to be lacking in providing sufficient location information for efficient spatial decision making.
INTERNATIONAL JOURNAL OF DIGITAL EARTH
(2021)
Article
Sociology
Tse-Chuan Yang, Seulki Kim, Stephen A. Matthews
Summary: This study examines the mechanisms of social capital and socio-behavior that potentially link unemployment rates to opioid-related mortality. The findings suggest that high unemployment rates indirectly contribute to opioid-related mortality through decreased social capital, increased social isolation, and higher prevalence of smoking. These pathways are stronger in counties of states experiencing a rapid growth in opioid-related mortality rates.
Article
Geography
Tse-Chuan Yang, Seulki Kim, Stephen A. Matthews
Summary: In New York City, there is significant variation in face mask violation rates and COVID-19-related death rates, with similar spatial distributions, higher rates found in Brooklyn and the Bronx. The positive association between police-enforced face mask violation rates and COVID-19-related death rates persists, and is linked to specific ethnicities and limited English proficiency in households. This study expands the COVID-19 literature by highlighting more aggressive enforcement of face mask rules in certain minority and limited English proficiency communities.
PROFESSIONAL GEOGRAPHER
(2021)
Article
Health Care Sciences & Services
Soheil Hashtarkhani, Behzad Kiani, Alireza Mohammadi, Shahab MohammadEbrahimi, Mohammad Dehghan-Tezerjani, Tahereh Samimi, Mahmood Tara, Stephen A. Matthews
Summary: This study aimed to describe the characteristics of EMS callers and analyze the space-time distribution of emergency requests in a large urban area. It found that high-response time clustered areas had a low overlap with general spatial clusters, suggesting unknown factors influencing response times. This research can help policymakers allocate resources and implement interventions to enhance urban EMS systems.
Article
Biology
Soheil Hashtarkhani, Behzad Kiani, Alireza Mohammadi, Shahab MohammadEbrahimi, Saeid Eslami, Mahmood Tara, Stephen A. Matthews
Summary: Emergency Medical Services (EMS) is the primary contact point for people in critical condition and in need of urgent healthcare. In Iran, as in other countries, a lack of adequate EMS-related infrastructure often results in people in need of emergency services dying or suffering permanent injuries. By examining the response times and spatiotemporal patterns of EMS calls, improvements can be made to time-sensitive patient outcomes.
BMC RESEARCH NOTES
(2022)
Article
Demography
Federico Benassi, Massimiliano Crisci, Stephen A. Matthews, Stefania M. L. Rimoldi
Summary: This study examines the residential segregation of migrants in Rome and Milan over the past two decades, using original and partially unpublished data. A 5-class concentric ring typology is introduced to analyze the spatial distribution of four selected foreign nationalities, revealing heterogeneity in overall and nationality-specific patterns. The findings highlight the complexity of urban demographics in Italy and raise questions about current theories of residential segregation in Southern European cities.
Article
Public, Environmental & Occupational Health
Tse-Chuan Yang, Stephen A. Matthews, Feinuo Sun
Summary: This study examines the heterogeneity of the associations between social determinants and COVID-19 fully vaccinated rate using a multiscale geographically weighted regression. The findings suggest that the percentage of Republican votes, demographic compositions, and local spatial processes play important roles in shaping fully vaccinated rates. This challenges the 1-size-fits-all approach and highlights the importance of a place-based perspective in ecological health research.
AMERICAN JOURNAL OF PREVENTIVE MEDICINE
(2022)
Article
Social Sciences, Interdisciplinary
R. L'Heureux Lewis-Mccoy, Natasha Warikoo, Stephen A. Matthews, Nadirah Farah Foley
Summary: This introduction focuses on suburban inequality and highlights the gaps in our understanding of how inequality operates in suburban communities. It covers various aspects such as measurement, forgotten scholarship, demographic change, poverty, social supports, race, immigration, education, politics, policing, and future directions for suburban studies.
RSF-THE RUSSELL SAGE JOURNAL OF THE SOCIAL SCIENCES
(2023)
Article
Social Sciences, Interdisciplinary
R. L'heureux Lewis-Mccoy, Natasha Warikoo, Stephen A. Matthews, Nadirah Farah Foley
Summary: This introduction addresses the limited related scholarship on suburban inequality, describes how inequality unfolds differently in suburban communities than in urban and rural communities, and draws attention to urgent issues related to stratification between and within suburban communities. The critical review covers areas such as measurement, forgotten suburban scholarship, demographic change, suburban poverty, social supports, race, immigration, education, politics, policing, and future directions for suburban studies. In our call for resisting amnesia, we also draw attention to forgotten suburban histories and studies of a diverse range of suburban communities.
RSF-THE RUSSELL SAGE JOURNAL OF THE SOCIAL SCIENCES
(2023)
Article
Health Care Sciences & Services
Soheil Hashtarkhani, Stephen A. Matthews, Ping Yin, Alireza Mohammadi, Shahab MohammadEbrahimi, Mahmood Tara, Behzad Kiani
Summary: This study combines GIS with mathematical optimization to improve EMS coverage in a county in northeast Iran. EMS demand locations were determined through analysis of one-year EMS call data. Two scenarios were implemented, including a relocation model for existing ambulances and an allocation model for new ambulances, using a list of candidate locations. The incorporation of GIS techniques into optimization modeling shows promise for efficient management of healthcare resources.
Article
Geriatrics & Gerontology
Tse-Chuan Yang, Seulki Kim, Stephen A. Matthews, Carla Shoff
Summary: This study explores the relationship between social vulnerability and the prevalence of opioid use disorder (OUD) among older adults. The findings suggest that higher social vulnerability is associated with a higher prevalence of OUD. Furthermore, the correlates of OUD prevalence vary across different levels of social vulnerability.
JOURNALS OF GERONTOLOGY SERIES B-PSYCHOLOGICAL SCIENCES AND SOCIAL SCIENCES
(2023)
Editorial Material
Public, Environmental & Occupational Health
Brittany Victoria Barber, George Kephart, Ruth Martin-Misener, Michael Vallis, Stephen Matthews, Lou Atkins, Christine Cassidy, Janet Curran, Daniel Rainham
Summary: The long-term economic viability of modern health care systems is uncertain due to increasing costs of health care at the end of life and the rising utilization associated with multiple chronic diseases. Preventive investments in reducing disease risk are necessary to control health care spending and sustain delivery of services. Behavior change interventions have proven effective in reducing risk and preventing chronic diseases, however, large-scale efforts to reduce population-level chronic diseases are challenging. This paper suggests integrating health geography and behavioral economics principles to strengthen behavior change interventions for chronic disease prevention by disrupting high-risk behavior patterns with context-specific interventions.
TRANSLATIONAL BEHAVIORAL MEDICINE
(2023)
Article
Geography
Samantha L. Powers, Stephen A. Matthews, Andrew J. Mowen
Summary: Social capital provides important benefits for health, economy, and community, particularly connections between diverse individuals. Research has shown significant spatial variation in the relationships between racial, ethnic, and income diversity and social capital across the United States, emphasizing the need for more attention to local variation.
Article
Demography
Stephen A. Matthews, Laura Stiberman, James Raymer, Tse-Chuan Yang, Ezra Gayawan, Sayambhu Saita, Sai Thein Than Tun, Daniel M. Parker, Deborah Balk, Stefan Leyk, Mark Montgomery, Katherine J. Curtis, David W. S. Wong
SPATIAL DEMOGRAPHY
(2021)
Article
Geography
Hamidreza Rabiei-Dastjerdi, Stephen A. Matthews
Summary: Urban spatial inequality is multidimensional and complex. This study combines data on accessibility, environmental conditions, and socio-economic conditions to derive a composite index for Tehran, Iran. The findings contribute to the evidence-base on urban spatial inequality and may inform urban policy decisions aimed at reducing spatial inequality.
REGIONAL SCIENCE POLICY AND PRACTICE
(2021)