Integrated safety profile of selinexor in multiple myeloma: experience from 437 patients enrolled in clinical trials
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Title
Integrated safety profile of selinexor in multiple myeloma: experience from 437 patients enrolled in clinical trials
Authors
Keywords
-
Journal
LEUKEMIA
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-02-24
DOI
10.1038/s41375-020-0756-6
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- Global Burden of Multiple Myeloma
- (2018) Andrew J. Cowan et al. JAMA Oncology
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- Promising activity of selinexor in the treatment of a patient with refractory diffuse large B-cell lymphoma and central nervous system involvement
- (2017) Sabela Bobillo et al. HAEMATOLOGICA
- 2016 MASCC and ESMO guideline update for the prevention of chemotherapy- and radiotherapy-induced nausea and vomiting and of nausea and vomiting in advanced cancer patients
- (2016) F. Roila et al. ANNALS OF ONCOLOGY
- Carfilzomib and dexamethasone versus bortezomib and dexamethasone for patients with relapsed or refractory multiple myeloma (ENDEAVOR): a randomised, phase 3, open-label, multicentre study
- (2016) Meletios A Dimopoulos et al. LANCET ONCOLOGY
- Next-generation XPO1 inhibitor shows improved efficacy and in vivo tolerability in hematological malignancies
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- (2014) Ho Yee Joyce Fung et al. SEMINARS IN CANCER BIOLOGY
- Genome-wide studies in multiple myeloma identify XPO1/CRM1 as a critical target validated using the selective nuclear export inhibitor KPT-276
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- CRM1 inhibition induces tumor cell cytotoxicity and impairs osteoclastogenesis in multiple myeloma: molecular mechanisms and therapeutic implications
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- A phase 2 study of single-agent carfilzomib (PX-171-003-A1) in patients with relapsed and refractory multiple myeloma
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- Selective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemia
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- Safety and efficacy of single-agent lenalidomide in patients with relapsed and refractory multiple myeloma
- (2009) P. Richardson et al. BLOOD
- Treatment of cancer-related anorexia with olanzapine and megestrol acetate: a randomized trial
- (2009) Rudolph M. Navari et al. SUPPORTIVE CARE IN CANCER
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