Article
Biochemistry & Molecular Biology
Chun-Yi Tsai, Keng-Hao Liu, Cheng-Chou Lai, Jun-Te Hsu, Shun -Wen Hsueh, Chia-Yen Hung, Kun-Yun Yeh, Yu-Shin Hung, Yung -Chang Lin, Wen-Chi Chou
Summary: This study aimed to investigate the association between frailty and postoperative delirium (POD) in aged cancer patients undergoing elective abdominal surgery. It found that frailty status was an independent risk factor for POD occurrence. Thus, preoperative assessment of frailty in older cancer patients is important in order to improve postoperative care.
BIOMEDICAL JOURNAL
(2023)
Article
Neurosciences
Zhiqiang Chen, Quanshui Hao, Rao Sun, Yanjing Zhang, Hui Fu, Shile Liu, Chenglei Luo, Hanwen Chen, Yiwen Zhang
Summary: The study aimed to investigate the relationship between preoperative geriatric nutritional risk index (GNRI) and postoperative delirium (POD) in elderly patients after cardiac surgery, and to evaluate the additional value of GNRI in predicting POD. Results showed that patients with lower GNRI scores had a higher risk of developing POD. The addition of GNRI improved the predictive accuracy in some models.
CNS NEUROSCIENCE & THERAPEUTICS
(2023)
Article
Geriatrics & Gerontology
Frances Y. Hu, Lynne O'Mara, Samir Tulebaev, Ariela R. Orkaby, Zara Cooper, Rachelle E. Bernacki
Summary: Geriatric service involvement addresses a high burden of both geriatric and palliative care needs in older EGS patients. Geriatric recommendations may direct interventions for surgical education in fundamental geriatric and palliative care knowledge to maximize geriatric resources for the most high-risk patients.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2022)
Article
Oncology
Kotaro Yamashita, Makoto Yamasaki, Tomoki Makino, Koji Tanaka, Takuro Saito, Kazuyoshi Yamamoto, Tsuyoshi Takahashi, Yukinori Kurokawa, Yukiko Yasunobe, Hiroshi Akasaka, Hiromi Rakugi, Kiyokazu Nakajima, Hidetoshi Eguchi, Yuichiro Doki
Summary: Preoperative comprehensive geriatric assessment (CGA) is associated with the risk of postoperative complications in older patients with esophageal cancer. Patients in the frail group have a higher incidence of postoperative complications, longer hospitalization time, and lower survival rate.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Geriatrics & Gerontology
Janani Thillainadesan, Sarah J. Aitken, Sue R. Monaro, John S. Cullen, Richard Kerdic, Sarah N. Hilmer, Vasi Naganathan
Summary: This study evaluates the impact of a novel model of care called Geriatric Comanagement of Older Vascular surgery inpatients, showing a reduction in hospital-acquired geriatric syndromes and delirium after implementation, with more significant effects observed in frail patients.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2022)
Article
Chemistry, Medicinal
Jin-Jin Yang, Lei Lei, Di Qiu, Sai Chen, Jing-Wei Zhao, Yuan -Yuan Mao, Jian-Jun Yang
Summary: This randomized controlled trial aimed to evaluate the relationship between remimazolam and postoperative delirium in older adult patients undergoing orthopedic surgery. The incidence of postoperative delirium in the remimazolam group was 15.6%, while it was 12.4% in the propofol group, with no significant difference observed. Although patients in the remimazolam group had a lower incidence of hypotension and consumed fewer vasoactive drugs intraoperatively, they experienced longer postoperative extubation time and PACU stay.
DRUG DESIGN DEVELOPMENT AND THERAPY
(2023)
Review
Medicine, General & Internal
Yu He, Wenchen Zou, Xiaochai Han, Caitao Chen, Anren Zhang, Nianyi Sun
Summary: The aging population and advancements in surgery and anesthesia have led to a greater need for surgical services for geriatric patients. Neurocognitive disorders are common complications experienced by older individuals after surgery. Improving perioperative brain health in older adults has become crucial for multidisciplinary perioperative care teams. This systematic review aims to assess the effectiveness and safety of cognitive prehabilitation programs for geriatric patients undergoing elective surgery.
Article
Geriatrics & Gerontology
Richard D. Shih, Christopher R. Carpenter, Vaishal Tolia, Ellen F. Binder, Joseph G. Ouslander
Summary: The article discusses the publication and endorsement of the Geriatric Emergency Department (GED) Guidelines in 2014, the challenges in implementing the guidelines in emergency departments, and the realistic expectations for non-Geriatric ED accredited institutions.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2022)
Review
Emergency Medicine
Fei Chen, Libo Liu, Yetong Wang, Ying Liu, Luodan Fan, Junting Chi
Summary: This meta-analysis examined the prevalence of delirium and its related factors among geriatric emergency department patients. The findings indicated that delirium is common in geriatric patients in the emergency department, and its prevalence is influenced by factors such as region, age, and sample size. It is recommended to enhance screening, prevention, and treatment of delirium in geriatric patients, and implement appropriate interventions to reduce its occurrence and adverse outcomes.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2022)
Article
Medicine, General & Internal
Yanan Song, Yajie Liu, Yi Yuan, Xixi Jia, Wenchao Zhang, Geng Wang, Yunyang Jia, Xiaoxiao Wang, Lei Liu, Weitian Li, Xinping Li, Nan Cai, Chang Liu, Yue Li, Yongzheng Han, Yang Zhou, Xinning Mi, Chengmei Shi, John Q. Wang, Alain Vuylsteke, Xiangyang Guo, Zhengqian Li
Summary: This study compared the impact of subarachnoid anesthesia (SA) and general anesthesia (GA) on melatonin secretion, sleep circadian rhythm, and postoperative delirium in elderly hip fracture surgery patients. Results showed that SA had less disruption on melatonin rhythm and sleep patterns, and lower incidence of postoperative delirium compared to GA.
Article
Medicine, General & Internal
Hyun-Jung Shin, Soo Lyoen Choi, Hyo-Seok Na
Summary: Postoperative delirium remains a challenge in cardiac surgery, with no significant difference in incidence between patients receiving sevoflurane and dexmedetomidine-based versus propofol-based anesthesia. The only notable difference was a lower occurrence of hyperactive delirium in the former group. Older age, lower preoperative albumin levels, and emergency surgery were identified as significant risk factors for postoperative delirium.
Article
Surgery
Sean J. Donohue, Caroline E. Reinke, Susan L. Evans, Mary M. Jordan, Yancey E. Warren, Timothy Hetherington, Marc Kowalkowski, Addison K. May, Brent D. Matthews, Samuel W. Ross
Summary: This study evaluated the use of laparoscopic surgery in emergency general surgery procedures and found that it was associated with improved outcomes, while open surgery was highly correlated with inpatient mortality. Conversion to open surgery was a protective factor at all time points.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Anesthesiology
Jun Ma, Chuanyao Li, Wei Zhang, Ling Zhou, Shuhua Shu, Sheng Wang, Di Wang, Xiaoqing Chai
Summary: This study investigated the effect of preoperative anxiety on postoperative delirium and found that patients with anxiety had a higher incidence of delirium. Age, alcohol abuse, history of stroke, HADS-A scores, and education level were identified as predictors of delirium. Early intervention for preoperative anxiety may be effective in preventing delirium among total hip arthroplasty patients.
BMC ANESTHESIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Yusuke Iizuka, Koichi Yoshinaga, Kyosuke Takahashi, Sayaka Oki, Yoshihiko Chiba, Masamitsu Sanui, Naoyuki Kimura, Atsushi Yamaguchi
Summary: This prospective observational study aimed to measure pre- and postoperative plasma ascorbic acid levels and examine their association with delirium. The results showed that lower postoperative plasma ascorbic acid levels may be associated with the development of delirium in patients undergoing cardiovascular surgery.
JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE
(2023)
Article
Surgery
Lakshika Tennakoon, Nicholas A. Hakes, Aussama K. Nassar, David A. Spain, Lisa M. Knowlton
Summary: Emergency general surgery among cardiac surgery patients is increasingly common and consequential. In this retrospective analysis of hospitalized complex cardiac patients, it was found that those who underwent emergency general surgery had significantly higher mortality rates, longer length of stays, higher rates of nonroutine discharge, and higher hospitalization costs compared to those who did not. These findings highlight the significant impact of emergency general surgery on cardiac surgery patients.
JOURNAL OF SURGICAL RESEARCH
(2023)
