Editorial Material
Biochemistry & Molecular Biology
Richard Huskey
Summary: Gossip is more than just trash talk, it can influence behavior, foster cooperation, and increase group affiliation.
Editorial Material
Ecology
Patricia C. Lopes
Summary: An infection can lead to significant changes in the physiology and behavior of the host, affecting other organisms both inside and outside the host's body, with important ecological implications. Therefore, it is important to increase awareness and integration of these potential 'off-host' effects.
TRENDS IN ECOLOGY & EVOLUTION
(2023)
Article
Biochemistry & Molecular Biology
Elis Cristina Araujo Eleutherio, Rayne Stfhany Silva Magalhaes, Aline de Araujo Brasil, Jose Raphael Monteiro Neto, Luan de Holanda Paranhos
Summary: During cellular respiration, radicals like superoxide can cause cell damage, but cells use the enzyme Cu/Zn Superoxide Dismutase (SOD1) to convert superoxide into oxygen and hydrogen peroxide. In addition to its primary function, SOD1 also plays other roles, such as activating gene transcription or functioning as an RNA binding protein.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
(2021)
Article
Ethics
Anuj B. Mehta, Matthew K. Wynia
Summary: The article describes the inclusion of triage algorithms and other strategies in crisis standards of care plans, sparking vigorous debates on prioritizing patient survival predictions and values like equity in triage protocols. While the development of CSC triage protocols is based in medicine, public health, and ethics, the activation of CSC plans is ultimately a political decision.
HASTINGS CENTER REPORT
(2021)
Article
Biochemistry & Molecular Biology
Guillermo H. Jimenez Aleman, Venkatesh P. Thirumalaikumar, Georg Jander, Alisdair R. Fernie, Aleksandra Skirycz
Summary: The oxylipin 12-oxo-phytodienoic acid (OPDA) is a biosynthetic precursor of the plant hormone jasmonic acid, but also functions as a signaling molecule independent of jasmonates. OPDA is involved in various biological processes across plant species, including defense and stress responses, growth regulation, and development. This article summarizes what is known about OPDA metabolism and signaling, discussing its jasmonate dependent and independent roles, as well as open questions regarding the OPDA protein interactome and biological roles of OPDA conjugates.
Review
Immunology
Le Xiong, Stephen L. L. Nutt, Cyril Seillet
Summary: Innate lymphoid cells (ILCs) serve as a link between sensory cells and effector cells, contributing to tissue homeostasis and adaptation to changing environmental conditions. Studying the non-canonical functions of these cells provides insights into their regulation and adaptability.
FRONTIERS IN IMMUNOLOGY
(2022)
Review
Biotechnology & Applied Microbiology
Matthias W. Laschke, Thomas Spaeter, Michael D. Menger
Summary: Adipose tissue-derived microvascular fragments have the ability to rapidly reassemble into microvascular networks, exhibit angiogenic activity, and serve as a source of endothelial progenitor cells and multipotent mesenchymal stromal cells. They also play a crucial role in tissue integration of implanted biomaterials.
TRENDS IN BIOTECHNOLOGY
(2021)
Review
Microbiology
J. Knisz, R. Eckert, L. M. Gieg, A. Koerdt, J. S. Lee, E. R. Silva, T. L. Skovhus, B. A. An Stepec, S. A. Wade
Summary: Microbiologically influenced corrosion (MIC) is a growing concern affecting various materials and sectors. Despite the global efforts to address MIC, there is limited interdisciplinary collaboration and information sharing. This review emphasizes the importance of non-biological aspects in understanding MIC and proposes approaches to tackle MIC-related challenges. It also highlights the need for microbiologists' expertise in advancing this field. Overall, this review aims to bridge the siloed nature of MIC research and encourage microbiologists to contribute to this important topic.
FEMS MICROBIOLOGY REVIEWS
(2023)
Article
Psychology, Biological
Aisling Rayne, Hitaua Arahanga-Doyle, Bethany Cox, Murray P. Cox, Catherine M. Febria, Stephanie J. Galla, Shaun C. Hendy, Kirsten Locke, Anna Matheson, Aleksandra Pawlik, Tom Roa, Emma L. Sharp, Leilani A. Walker, Krushil Watene, Priscilla M. Wehi, Tammy E. Steeves
Summary: The current science system is unfair in its memberships, outputs, and outcomes. We advocate for collective action to establish a more just science system that shows care for all participants. To achieve this, we urge the science community to harness complexity processes with intention.
NATURE HUMAN BEHAVIOUR
(2023)
Editorial Material
Hematology
Bethany T. Samuelson Bannow
Summary: In the largest meta-analysis to date on the topic, Valeriani et al identified 4 clear benefits of using anticoagulation to treat splanchnic vein thrombosis (SVT), including increased recanalization, decreased thrombosis progression, decreased major bleeding, and decreased mortality.
Review
Cell Biology
Tautvydas Paskevicius, Rabih Abou Farraj, Marek Michalak, Luis B. Agellon
Summary: Calnexin is an integral ER membrane protein with distinct domains in the ER lumen and cytosol. It acts as a chaperone for folding and quality control of proteins, similar to calreticulin. Recent studies have shown that the cytosolic domain of calnexin undergoes post-translational modifications and interacts with various proteins, suggesting its role in coordinating ER functions with cytosolic events.
Editorial Material
Oncology
Song Chen, Andrew D. Luster
Summary: The study identifies that histamine released during allergic reactions and from tumor cells weakens the response to immunotherapy. Histamine H-1-receptor signaling induces a suppressive phenotype in tumor-associated macrophages and increases VISTA expression, thereby suppressing CD8(+) T cell function. Anti-histamines can reverse these effects and improve the efficacy of immunotherapy.
Review
Biochemistry & Molecular Biology
Yu-Hsuan Lee, Daan Ren, Byungsun Jeon, Hung-wen Liu
Summary: This review summarizes recent advances in the study of S-adenosyl-l-methionine (SAM) utilizing enzymes. SAM is a naturally occurring molecule that is commonly associated with methyltransfer reactions. However, it has been found that SAM can also donate other moieties during natural product biosynthetic reactions. The review focuses on the discovery of novel SAM utilizing enzymes and the role of SAM in sulfonium chemistry.
NATURAL PRODUCT REPORTS
(2023)
Review
Endocrinology & Metabolism
Hannah A. Taylor, Lena Przemylska, Eva M. Clavane, Paul J. Meakin
Summary: This review focuses on the research of beta-site amyloid precursor protein cleaving enzyme-1 (BACE1) and its role in metabolic diseases. It discusses the regulation of BACE1, its effect on metabolism, and the possibility of using BACE1 inhibitors as a treatment for obesity and its comorbidities. The study finds that BACE1 is expressed not only in the brain but also in various cell types, and its dysregulation is implicated in the development of metabolic diseases. Additionally, BACE1 knockout models and clinical trials of BACE1 inhibitors suggest a physiological role of BACE1 in energy metabolism and weight regulation.
Review
Agriculture, Multidisciplinary
Beatriz Gonzalez-Munoz, Fernanda Garrido-Vargas, Carolina Pavez, Fernando Osorio, Jianshe Chen, Edmundo Bordeu, Jose A. O'Brien, Natalia Brossard
Summary: Red wines are characterized by astringency, which is influenced by factors like tannins, salivary proteins, and anthocyanins. These interactions lead to different tactile sensations and require further research, particularly regarding the origins and development of astringency.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2022)
