Article
Clinical Neurology
Jianghong Liu, Andrea L. Glenn, Naixue Cui, Adrian Raine
Summary: The study found bidirectional relationships between sleep problems and behavior problems, indicating that early interventions targeting both issues may effectively prevent the aggravating health-behavior cycle.
Article
Psychology, Clinical
Darlynn M. Rojo-Wissar, Juliana Acosta, Karissa DiMarzio, Megan Hare, Chelsea F. Dale, Wesley Sanders, Justin M. Parent
Summary: This study examines the mediating role of sleep in the association between screen media activity (SMA) and youth behavioral health. The results show that SMA is associated with sleep disturbance and shorter sleep duration, and sleep disturbance is associated with worse behavioral health in youth. Sleep (including disturbance and duration) may partially account for the small associations observed between SMA and worse behavioral health in youth.
CHILD AND ADOLESCENT MENTAL HEALTH
(2023)
Article
Psychology, Developmental
Eoin McElroy, Philip Hyland, Mark Shevlin, Thanos Karatzias, Frederique Vallieres, Menachem Ben-Ezra, Maria Louison Vang, Boris Lorberg, Dmytro Martsenkovskyi
Summary: This study aims to estimate the degree of change in the mental health problems of Ukrainian children following Russia's invasion in February 2022 and to identify the risk factors associated with these changes. The results show that the ongoing war in Ukraine has led to an increase in common mental health problems among children. Further research is needed to determine the extent and consequences of this increase and to develop intervention strategies for those most in need.
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
(2023)
Article
Psychology, Developmental
Alexander Neumann, Alexia Jolicoeur-Martineau, Eszter Szekely, Hannah M. Sallis, Kieran O'Donnel, Celia M. T. Greenwood, Robert Levitan, Michael J. Meaney, Ashley Wazana, Jonathan Evans, Henning Tiemeier
Summary: The study found that PRS based on current GWAS of psychiatric phenotypes tends to be associated with general psychopathology, or both general and specific psychiatric domains, but not with one specific psychopathology domain only. Furthermore, PRSs can be combined to improve predictive ability. Users of PRS should be aware of nonspecificity and consider using multiple PRSs simultaneously when predicting psychiatric disorders.
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
(2022)
Article
Pediatrics
Gangsan Kim, Jiyoon Shin, Jae-Won Kim
Summary: The study investigates the effects of childhood trauma, internalizing symptoms, and externalizing symptoms on suicidality among adolescents. Childhood trauma has both direct and indirect effects on suicidality, through internalizing and externalizing symptoms. Internalizing symptoms directly influence suicidality, while externalizing symptoms indirectly influence suicidality through internalizing symptoms. These findings suggest that therapeutic interventions targeting both internalizing and externalizing symptoms may be crucial in preventing suicide in adolescents with childhood trauma.
CHILD AND ADOLESCENT PSYCHIATRY AND MENTAL HEALTH
(2021)
Article
Substance Abuse
Ashley L. L. Watts, David Watson, Andrew C. C. Heath, Kenneth J. J. Sher
Summary: Alcohol use disorder is often comorbid with other forms of psychopathology. This study found that different combinations of symptoms within alcohol use disorder can lead to disorder-specific expressions as well as tendencies towards externalizing and internalizing psychopathology.
Editorial Material
Biochemistry & Molecular Biology
Valentina Carpentieri, Silvia Cugno, Katarina Lockic, Esterina Pascale, Walter Adriani
Summary: Epigenetic modifications, specifically changes in DNA methylation, have been found to serve as biomarkers for predicting infant/adolescent psychopathology. Methylation changes in the DAT1/SLC6A3 gene have been linked to initial severe ADHD and the response to therapy. The study also suggests that genotype and family environment may influence symptomatology. These biomarkers can be used to predict internalizing or externalizing symptoms and involve ADHD-like psycho-pathological characteristics.
Article
Psychology, Developmental
Francesca Locati, Ilaria Maria Antonietta Benzi, Alberto Milesi, Chloe Campbell, Nicholas Midgley, Peter Fonagy, Laura Parolin
Summary: This study examined the associations between mentalization, epistemic trust, and psychopathology in adolescents. Results showed that in females, epistemic trust mediated the relationship between mentalization and psychopathology, while in males, mentalization and epistemic trust had independent associations with psychopathology.
JOURNAL OF ADOLESCENCE
(2023)
Article
Psychology, Developmental
Maria Sanchez, Jennifer C. Bullen, Matthew C. Zajic, Nancy McIntyre, Peter Mundy
Summary: This study examined differences in internalizing and externalizing behaviors between boys and girls diagnosed with autism spectrum disorder (ASD). Girls showed higher instances of bullying, less anger control, and poorer emotional self-control compared to boys. There were no differences between the groups in terms of social communication. Further research is needed to investigate the lesser known area of externalizing behaviors in girls with ASD.
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
(2022)
Article
Pediatrics
Tsz Wing Ivy Lau, Choon Guan Lim, Sanchalika Acharryya, Nikki Lim-Ashworth, Yi Ren Tan, Shuen Sheng Daniel Fung
Summary: Gender differences in ADHD comorbidities exist in the Asian clinical population, with females showing less externalizing symptoms but more depressive symptoms compared to males. Socioeconomic status and parental use of physical punishment were significant predictors of internalizing and externalizing problems. More research is needed to improve the detection of ADHD in females and understand the biopsychosocial mechanisms underlying gender differences in ADHD.
CHILD AND ADOLESCENT PSYCHIATRY AND MENTAL HEALTH
(2021)
Review
Neurosciences
Xiaoyi Li, Kai Zhang, Xiao He, Jinyun Zhou, Chentao Jin, Lesang Shen, Yuanxue Gao, Mei Tian, Hong Zhang
Summary: Recent neuroimaging studies have provided insights into the neurobiological processes associated with ASD, with MRI revealing abnormal developmental trajectories, functional MRI highlighting disrupted neural networks, and PET/SPECT imaging indicating metabolic and neurotransmitter abnormalities contributing to aberrant neural circuits in ASD.
NEUROSCIENCE BULLETIN
(2021)
Article
Clinical Neurology
Keiko Murakami, Mami Ishikuro, Taku Obara, Aoi Noda, Fumihiko Ueno, Tomomi Onuma, Fumiko Matsuzaki, Ippei Takahashi, Saya Kikuchi, Natsuko Kobayashi, Hirotaka Hamada, Noriyuki Iwama, Hirohito Metoki, Masahiro Kikuya, Masatoshi Saito, Junichi Sugawara, Hiroaki Tomita, Nobuo Yaegashia, Shinichi Kuriyama
Summary: This study aimed to examine the associations between maternal postnatal bonding disorder and emotional/behavioral problems in preschool children. The study found that postnatal bonding disorder was associated with an increased risk of emotional/behavioral problems in children, as well as internalizing and externalizing problems.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Psychology, Multidisciplinary
Jeremie Richard, Caroline Temcheff, Emilie Fletcher, Annie Lemieux, Jeffrey Derevensky, Michele Dery
Summary: The study found that children with internal and/or external problems are more likely to develop symptoms of gaming disorder in adolescence; the development of internal problems over time significantly predicts symptoms of gaming disorder; the initial levels of internal and external problems are also associated with symptoms of gaming disorder.
COMPUTERS IN HUMAN BEHAVIOR
(2022)
Article
Psychiatry
Shilong Tang, Xianfan Liu, Lisha Nie, Zhuo Chen, Qiying Ran, Ling He
Summary: This study explored the feasibility of using quantitative magnetic resonance imaging techniques for the diagnosis of children with ADHD comorbid autistic traits (ATs). The results showed that children with ADHD-ATs had lower iron content and cerebral blood flow compared to children with ADHD without ATs. Quantitative magnetic resonance techniques can distinguish children with ADHD-ATs.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Psychiatry
Shilong Tang, Xianfan Liu, Lisha Nie, Fangfang Qian, Wushang Chen, Ling He
Summary: This study aimed to investigate the feasibility of three-dimensional pseudocontinuous arterial spin labeling (3D-pcASL) perfusion imaging in the brain of children with Attention-deficit/hyperactivity disorder (ADHD). The study compared and analyzed the brain gray and white matter volume as well as cerebral blood flow (CBF) perfusion values in ADHD children and healthy children. The results showed that ADHD children had lower total brain volume, total CBF values, gray and white matter volumes, and gray matter CBF values compared to healthy children.
FRONTIERS IN PSYCHIATRY
(2023)
Article
Psychology, Clinical
Yllza Xerxa, Leslie A. Rescorla, Lilly Shanahan, Henning Tiemeier, William E. Copeland
Summary: This study found that childhood loneliness is associated with anxiety and depressive disorders in young adults, suggesting that loneliness may have long-term effects on mental health. The study highlights the importance of early intervention to prevent loneliness and its consequences.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychology, Developmental
Sara Sammallahti, Elisa Holmlund-Suila, Runyu Zou, Saara Valkama, Jenni Rosendahl, Maria Enlund-Cerullo, Helena Hauta-Alus, Marius Lahti-Pulkkinen, Hanan El Marroun, Henning Tiemeier, Outi Makitie, Sture Andersson, Katri Raikkonen, Kati Heinonen
Summary: Higher maternal vitamin D concentration during pregnancy is associated with better child mental health, particularly in relation to negative affectivity, a trait indicating increased risk of psychopathology. The study found that higher maternal early/mid-pregnancy vitamin D levels were associated with lower negative affectivity in infants, while cord blood vitamin D levels showed less clear associations. These findings suggest that maternal vitamin D status during early- and mid-pregnancy may play a role in the behavioral development of offspring.
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
(2023)
Article
Psychology, Clinical
Scott W. Delaney, Yllza Xerxa, Ryan L. Muetzel, Tonya White, Sebastien Haneuse, Kerry J. Ressler, Henning Tiemeier, Laura D. Kubzansky
Summary: The study suggests that positive prenatal family environments may have lasting benefits on white matter neurodevelopment in preadolescence, which can reduce the risk of behavior problems.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Geriatrics & Gerontology
Amy Hofman, Maria Rodriguez-Ayllon, Meike W. Vernooij, Pauline H. Croll, Annemarie I. Luik, Alexander Neumann, Wiro J. Niessen, M. Arfan Ikram, Trudy Voortman, Ryan L. Muetzel
Summary: The study found bidirectional associations between physical activity and brain structure in middle-aged and older adults. Larger brain volumes and white matter microstructure at baseline were associated with higher levels of physical activity at follow-up. Additionally, lower baseline global mean diffusivity was associated with higher levels of walking at follow-up.
NEUROBIOLOGY OF AGING
(2023)
Article
Pediatrics
Farah Qureshi, Izzuddin M. Aris, Sheryl L. Rifas-Shiman, Wei Perng, Emily Oken, Janet Rich-Edwards, Andres Cardenas, Andrea A. Baccarelli, Michelle Bosquet Enlow, Mandy B. Belfort, Henning Tiemeier
Summary: This study investigated the association between leukocyte telomere length (LTL) at birth and markers of adiposity growth linked with cardiometabolic health later in life. The results suggest that LTL may be an early biomarker of altered adiposity growth, with shorter LTL being related to a later age of peak BMI for females and an earlier age of BMI rebound for both males and females.
Article
Psychiatry
Isabel K. Schuurmans, Sander Lamballais, Runyu Zou, Ryan L. Muetzel, Manon H. J. Hillegers, Charlotte A. M. Cecil, Annemarie I. Luik
Summary: Depressive symptoms vary in severity and stability over time, and high late-life depressive symptoms have been linked to poor brain health. To better understand the relationship between depressive symptoms and brain health, this study examined depressive symptom trajectories in middle age. The findings suggest that the impact of depressive symptoms on brain health may only become significant later in life.
JOURNAL OF PSYCHIATRIC RESEARCH
(2023)
Article
Psychology, Clinical
Wei-Chen Wang, Ming Ding, Susanne Strohmaier, Eva Schernhammer, Qi Sun, Jorge E. Chavarro, Henning Tiemeier
Summary: This study found an association between maternal healthy lifestyles and offspring depressive symptoms, which was mediated by offspring's healthy lifestyles.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychiatry
Koen Bolhuis, Lisa R. Steenkamp, Henning Tiemeier, Laura Blanken, Jean-Baptiste Pingault, Charlotte A. M. Cecil, Hanan El Marroun
Summary: This study found that there is an association between maternal childhood adversity and offspring childhood adversity, and offspring childhood adversity further mediates the relationship between maternal childhood adversity and offspring hallucinations and delusions.
SCHIZOPHRENIA BULLETIN
(2023)
Article
Psychology, Developmental
Iryna Culpin, Gemma Hammerton, Alan Stein, Marc H. Bornstein, Henning Tiemeier, Tim Cadman, Eivor Fredriksen, Jonathan Evans, Tina Miller, Esther Dermott, Jon Heron, Hannah M. Sallis, Rebecca M. Pearson
Summary: The present study suggests that the adverse effects of maternal postnatal depression on child development cannot be explained by various aspects of paternal involvement. Only father-child conflict has been identified as a risk factor for adverse child development and as a mediator in the association between maternal postnatal depression and child development. If found causal, interventions that reduce father-child conflict may improve developmental outcomes of children of mothers with postnatal depression.
DEVELOPMENTAL PSYCHOLOGY
(2023)
Article
Psychology, Developmental
Leontine W. ten Hoopen, Pieter F. A. de Nijs, Geerte Slappendel, Jan van der Ende, Dennis Bastiaansen, Kirstin Greaves-Lord, Leona Hakkaart-van Roijen, Manon H. J. Hillegers
Summary: This study found a significant association between fewer autism traits and better family functioning over time. This association was only significant in non-autistic children with autism traits. Families of children with autism traits but without a clinical diagnosis may face difficulties and lack support. Clinicians should consider offering support to these families to prevent family functioning problems.
Review
Endocrinology & Metabolism
Federica Sileo, Joris A. J. Osinga, W. Edward Visser, Toyah A. Jansen, Wichor M. Bramer, Arash Derakhshan, Valeria Citterio, Henning Tiemeier, Luca Persani, Tim I. M. Korevaar
Summary: Postpartum depression (PPD) has a significant impact on maternal and offspring well-being. This study found no association between thyroid function/TPOAb positivity and PPD through a population-based prospective cohort study, systematic literature review, and meta-analysis.
EUROPEAN JOURNAL OF ENDOCRINOLOGY
(2023)
Article
Endocrinology & Metabolism
Tessa A. Mulder, Purdey J. Campbell, Peter N. Taylor, Robin P. Peeters, Scott G. Wilson, Marco Medici, Colin Dayan, Vincent V. W. Jaddoe, John P. Walsh, Nicholas G. Martin, Henning Tiemeier, Tim I. M. Korevaar
Summary: This study found that the effects of many known thyroid function-related genes are already apparent in childhood, and some genes have a greater impact on children compared to adults. These findings provide new insights into the genetic regulation of thyroid function in early life.
EUROPEAN JOURNAL OF ENDOCRINOLOGY
(2023)
Article
Psychology, Developmental
Mannan Luo, Esther Walton, Alexander Neumann, Chris H. L. Thio, Janine F. F. Felix, Marinus H. van IJzendoorn, Irene Pappa, Charlotte A. M. Cecil
Summary: In this study, the researchers conducted an epigenome-wide association study and found that DNA methylation in neonates is associated with lateral ventricular volume (LVV) enlargement in childhood. This association persists into adulthood. The findings suggest that DNA methylation could serve as a potential marker for LVV.
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
(2023)
Article
Psychiatry
Anna Suleri, Charlotte Cecil, Anna-Sophie Rommel, Manon Hillegers, Tonya White, Lot D. de Witte, Ryan L. Muetzel, Veerle Bergink
Summary: This study examined the impact of prenatal infections on brain outcomes in adolescent offspring. The results showed negative associations between prenatal infection and cerebral white matter volume, as well as smaller volumes in certain frontotemporal regions of the brain. However, no effects of prenatal infection were observed on other measures of brain morphology, white matter microstructure, or functional connectivity.
TRANSLATIONAL PSYCHIATRY
(2023)
Article
Psychiatry
Fernando Estevez-Lopez, Hannah H. H. Kim, Monica Lopez-Vicente, Jeroen S. S. Legerstee, Manon H. J. Hillegers, Henning Tiemeier, Ryan L. L. Muetzel
Summary: Physical symptoms are symptoms for which no sufficient underlying root cause can be found through medical examinations. This study found a negative association between physical symptoms and surface area of the prefrontal cortex, suggesting a potential link between physical symptoms and brain morphology. Further research is needed to understand the longitudinal relationship between physical symptoms and brain changes.
TRANSLATIONAL PSYCHIATRY
(2023)
