Review
Chemistry, Physical
Ruben Comino-Garayoa, Jesus Pelaez, Celia Tobar, Veronica Rodriguez, Maria Jesus Suarez
Summary: This systematic review evaluated different pretreatments of zirconia surface and resin cement. It found that mechanicochemical surface pretreatments offered the best adhesive results, with self-adhesive cement and cement with 10-MDP performing the best in adhesion to zirconia. Artificial aging reduced adhesion, and storage in water for 30 days or thermocycling for 5000 cycles is recommended.
Article
Chemistry, Physical
Maher Saeed Hajjaj, Saeed Jamaan Alzahrani
Summary: This study evaluated the effect of different cleaning methods on the shear bond strength of resin cement to contaminated zirconia specimens. The application of ceramic primer before contamination did not preserve the bond strength, while cleaning the contaminated surface with hydrofluoric acid or KATANA(TM) Cleaner improved the bond strength.
Review
Polymer Science
Tongtong Ma, Jiajia Zhang, Shuoyao Sun, Wenqing Meng, Yan Zhang, Junling Wu
Summary: Polyetheretherketone (PEEK) is a popular material for dental applications due to its excellent chemical stability, biocompatibility, and mechanical qualities. However, its surface inertness limits its osseointegration and bonding strength. This review focuses on recent progress in treatment strategies, including surface modification and blending modification, to enhance the bonding strength and bioactivity of PEEK materials. Despite challenges, modified PEEK shows promise for dental applications.
EUROPEAN POLYMER JOURNAL
(2023)
Review
Nutrition & Dietetics
Laiza Steimbach, Ariela Victoria Borgmann, Gabriella Giandotti Gomar, Lucas Ventura Hoffmann, Renata Rutckeviski, Diancarlos Pereira de Andrade, Fhernanda Ribeiro Smiderle
Summary: Fungal fi-glucans have potential as adjuvants in cancer treatment by stimulating the immune system, but further research is needed to determine their efficacy due to the diversity in methodology and insufficient information.
CLINICAL NUTRITION
(2021)
Review
Dentistry, Oral Surgery & Medicine
Putsadeeporn Thammajaruk, Massimiliano Guazzato, Supawadee Naorungroj
Summary: The objective of this study was to review the literature and analyze the effectiveness of different cleaning methods on the bond strength of resin cement to zirconia under short- and long-term aging conditions. A total of 25 studies met the inclusion criteria and were included in the qualitative analyses. The results showed that cleaning contaminated zirconia with water, alcohol, or acid etching resulted in significantly lower bond strength compared to uncontaminated zirconia under both short- and long-term aging conditions, while alumina air-abrasion or cleaning with sodium hypochlorite showed comparable bond strength to uncontaminated zirconia.
Review
Polymer Science
Louis Hardan, Rim Bourgi, Naji Kharouf, Davide Mancino, Maciej Zarow, Natalia Jakubowicz, Youssef Haikel, Carlos Enrique Cuevas-Suarez
Summary: The study found that using specific techniques and additional strategies can significantly improve the bond strength of universal adhesives to dentin, and inhibitors and specific operating methods can enhance the bonding effect. However, certain methods such as shortening application time and dentin desensitizers may decrease the bond strength of universal adhesives to dentin.
Review
Pharmacology & Pharmacy
Sherri Dudal, Caterina Bissantz, Antonello Caruso, Pascale David-Pierson, Wouter Driessen, Erich Koller, Ben-Fillippo Krippendorff, Martin Lechmann, Andres Olivares-Morales, Axel Paehler, Caroline Rynn, Dietrich Turck, Arthur Van De Vyver, Ken Wang, Lotte Winther
Summary: In vitro and in vivo models are widely used in pharmacological research, but understanding their translational relevance and limitations is crucial for selecting appropriate disease models and predicting clinically effective drug doses. This review examines animal models used in ophthalmology, infectious diseases, oncology, autoimmune diseases, and neuroscience, highlighting challenges and the potential of personalized dosing strategies.
DRUG DISCOVERY TODAY
(2022)
Review
Medicine, General & Internal
Felita Clarissa Halim, Paolo Pesce, Nicola De Angelis, Stefano Benedicenti, Maria Menini
Summary: This study conducted a systematic review to compare the clinical outcomes of titanium and zirconia implant abutments. The results showed that titanium abutments have better mechanical resistance and slightly higher plaque accumulation but without significant inflammatory process. Furthermore, the esthetic outcomes were found to be more related to the thickness of the soft tissues rather than the abutment material.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Chemistry, Physical
Guillermo Grazioli, Louis Hardan, Rim Bourgi, Leina Nakanishi, Elie Amm, Maciej Zarow, Natalia Jakubowicz, Patrycja Proc, Carlos Enrique Cuevas-Suarez, Monika Lukomska-Szymanska
Summary: This study evaluated the bond strength of rebonded brackets after different residual adhesive removal methods, finding that the Er:YAG laser showed similar bond strength values to new brackets, while sandblasting, mechanical grinding, or direct flame treatment resulted in significantly lower bond strength values.
Review
Computer Science, Artificial Intelligence
Lucia Pepa, Luca Spalazzi, Marianna Capecci, Maria Gabriella Ceravolo
Summary: This study is a systematic review of automatic emotion recognition systems applied in real clinical contexts. The results show that most clinical applications focus on neuro-developmental, neurological and psychiatric disorders, with the aim of diagnosing, monitoring, or treating emotional symptoms. The study design is mostly observational for monitoring and diagnosis, and interventional for treatment. Video and audio signals are the most commonly used, and supervised shallow learning is the most popular approach for emotion recognition algorithms.
IEEE TRANSACTIONS ON AFFECTIVE COMPUTING
(2023)
Article
Chemistry, Multidisciplinary
Ming Zhou, Xiaoyu Zhang, Yaming Zhang, Ding Li, Zhe Zhao, Qing Wang, Kai Tang, Lina Niu, Fu Wang
Summary: This study focuses on the development of nanostructured glass-zirconia to improve the interface stability of dental zirconia substrate and veneered porcelain, addressing the issue of cohesive/adhesive fracture of veneered porcelain in dental practice.
Article
Dentistry, Oral Surgery & Medicine
Salma M. Fathy, Walid Al-Zordk, Mohammed E. Grawish, Micheal Swain
Summary: Recent improvements in monolithic zirconia with higher yttria content have shown significant enhancements in translucency and flexural strength. However, compared to glass ceramics, monolithic zirconia still lacks unique translucency and may sacrifice some mechanical performance while improving aesthetically. Careful consideration is needed when using thin sections of aesthetic zirconia structures, especially in high bearing stress areas.
Review
Medicine, General & Internal
Hisham Sabbagh, Yeganeh Khazaei, Uwe Baumert, Lea Hoffmann, Andrea Wichelhaus, Mila Janjic Rankovic
Summary: The bracket transfer accuracy of the indirect bonding technique (IDB) was investigated in this systematic review. The overall accuracy can be considered clinically acceptable. Silicone trays showed the highest accuracy among different types of trays.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Biochemistry & Molecular Biology
Ana Coelho, Ines Amaro, Beatriz Rascao, Ines Marcelino, Anabela Paula, Jose Saraiva, Gianrico Spagnuolo, Manuel Marques Ferreira, Carlos Miguel Marto, Eunice Carrilho
Summary: This study conducted a systematic review on the effect of different cavity disinfectants on restorations' adhesion and clinical success. Chlorhexidine was found to preserve adhesion to dentin, while EDTA and ethanol had positive results that should be further confirmed. The study also highlighted the importance of avoiding the use of disinfectants lacking scientific evidence, such as lasers or fluoridated agents, for cavity disinfection.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Medical Laboratory Technology
Sheila X. Soh, Tze Ping Loh, Sunil K. Sethi, Lizhen Ong
Summary: This systematic review summarized existing literature on the effectiveness of lipid removal techniques in reducing interference in clinical chemistry tests. High-speed centrifugation was consistently effective for 13 analytes, while lipid-clearing agents were uniformly effective for 7 analytes. Mixed results were reported for the remaining analytes, indicating the need for harmonized protocols and criteria for data analysis.
CLINICAL CHEMISTRY AND LABORATORY MEDICINE
(2022)
Article
Dentistry, Oral Surgery & Medicine
Mostafa M. A. Elkholy, William Nguyen Ha
Summary: The preparation of severely curved S-shaped double-curved root canals can be technically challenging. A novel root canal instrumentation technique is proposed, which modifies 2 techniques: the McSpadden crown-down technique and the tactile controlled activation technique. The proposed technique recommends 3 apical strokes after the initial engagement before withdrawal to minimize instrumentation time. This technique presents a new method of crown-down instrumentation that prevents overflaring and avoids instrument separation.
JOURNAL OF ENDODONTICS
(2021)
Article
Dentistry, Oral Surgery & Medicine
Lawrence Alvino, William Nguyen Ha, Wing Chuan Chan, Giampiero Rossi-Fedele
Summary: The article discusses the changes in TDIs management guidelines in recent years, adjusting emergency management plans, and providing support for those who are first exposed to trauma guidelines. The new guidelines are divided into primary and permanent teeth, as well as avulsions, listing the main changes in emergency management since 2012.
DENTAL TRAUMATOLOGY
(2021)
Article
Dentistry, Oral Surgery & Medicine
Mostafa M. A. Elkholy, Nawar Naguib Nawar, William Nguyen Ha, Shehabeldin Mohamed Saber, Hyeon-Cheol Kim
Summary: The study found that access cavity design has a greater impact on the lifespan of mandibular first molars than root canal preparation taper. Stress patterns migrate apically along the root surface, concentrating on the mesial aspect of the mesial root and the furcation area's outer surface.
JOURNAL OF ENDODONTICS
(2021)
Article
Chemistry, Physical
Abhishek Isaac Mathew, Silvia Chamin Lee, Giampiero Rossi-Fedele, George Bogen, Venkateshbabu Nagendrababu, William Nguyen Ha
Summary: This study compared the density and radiopacity of mineral trioxide aggregate (MTA) used as a root canal filling material with different compaction techniques. The Lawaty technique group demonstrated the highest mass and radiopacity but required more time for obturation.
Article
Dentistry, Oral Surgery & Medicine
William N. Ha, Gustavo S. Chaves, Daniel Decurcio, Carlos Estrela, Ove A. Peters, Giampiero Rossi-Fedele
Summary: The study evaluated the remaining dentin thickness after post space preparation and the fit of different prefabricated posts to root canal preparation systems. The findings indicated that many posts would result in less than 1 mm dentin thickness, therefore clinicians should choose posts that fit their root canal preparations to minimize dentin removal.
JOURNAL OF THE AMERICAN DENTAL ASSOCIATION
(2021)
Article
Dentistry, Oral Surgery & Medicine
Abhishek Isaac Mathew, Silvia C. Lee, William Nguyen Ha, Giampiero Rossi-Fedele, Esma J. Dogramaci
Summary: This study investigated the factors and characteristics of CBCT usage among endodontists in Australia and New Zealand, and found that the number of monthly prescriptions was significantly associated with the presence of on-site CBCT units and the number of years of CBCT usage. CBCT imaging is widely accepted and used in endodontics, and is helpful for decision making and treatment planning.
AUSTRALIAN ENDODONTIC JOURNAL
(2023)
Article
Dentistry, Oral Surgery & Medicine
Emilija D. Jensen, William Ha, Jenny Tan, Kelly J. Oliver, Sarbin Ranjitkar
Summary: This case report presents a rare occurrence of rapid resorption of primary teeth in a patient with X-linked inhibitor of apoptosis protein (XIAP/BIRC4) mutation-associated primary immunodeficiency. The study highlights the importance of regular clinical and radiographic review, as well as the need for a better understanding of the pathogenesis of rapid resorption for improved clinical care.
INTERNATIONAL JOURNAL OF PAEDIATRIC DENTISTRY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Emilija D. Jensen, Gabrielle Smart, Nara Lee, Jenny Tan, Kelly Oliver, William N. Ha, Sarbin Ranjitkar
Summary: This study investigated the prevalence and characteristics of molar-root incisor malformation (MRIM) in children seen at a specialist paediatric dental unit. The results showed that the prevalence of MRIM was 0.47% or 1:210 among 1054 children examined. All affected children had MRIM in their permanent first molars, with two children also having it in their primary second molars. They also had medical comorbidities and multiple exposures to general anesthesia before 4 years of age. Histological and microCT analyses revealed the presence of numerous microchannels connecting the pulp chamber to the external surface of the affected teeth at the furcation. Early detection of MRIM can prevent atypical odontogenic facial pain and infection.
INTERNATIONAL JOURNAL OF PAEDIATRIC DENTISTRY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Nawar Naguib Nawar, Mostafa M. A. Elkholy, William Nguyen Ha, Shehabeldin Mohamed Saber, Hyeon-Cheol Kim
Summary: This study used finite element analysis (FEA) to investigate the effect of shaping parameters of middle mesial canals (MMCs) on the biomechanical behavior and life span of a mandibular first molar. The results showed that shaping the MMC reduced the number of cycles until failure (NCF). The shaping size of 30/.06 resulted in a lower life span percentage compared to 25/.04 in both independent and confluent MMC models. Oblique loading had a greater impact on NCF than vertical loading. Therefore, conservative shaping of the MMC as 25/.04 is recommended, and whether the MMC is independent or confluent determines the choice of increasing apical diameter or root canal taper when larger shaping parameters are needed.
JOURNAL OF ENDODONTICS
(2023)
Article
Dentistry, Oral Surgery & Medicine
Nawar Naguib Nawar, Mostafa M. A. Elkholy, William Nguyen Ha, Sebastian Buerklein, Shehabeldin Mohamed Saber
Summary: Insufficient research has been conducted on the influence of social media on endodontic education. This study found that 98.4% of students use Facebook for endodontic knowledge. Despite knowing that scientific evidence is not always provided, students still find such information valuable as it demonstrates practical clinical cases. Most students turn to Facebook for endodontic education to bridge the gap between academic learning and clinical practice. The utilization of social media for education is a concerning phenomenon that should not be ignored by academic institutes.
AUSTRALIAN ENDODONTIC JOURNAL
(2023)
Article
Dentistry, Oral Surgery & Medicine
Yoseif Haddad, Wing Chuan Chan, William Nguyen Ha, Antonio Conde, Roberto Estevez, Alejandro Pena Lopez, Georgia Charlotte Gates, Giampiero Rossi-Fedele
Summary: This study evaluated the antimicrobial effectiveness of sodium hypochlorite (NaOCl) mixtures combined with Keratobacter (KB) in a biofilm root canal model. Different concentrations of NaOCl were mixed with KB to determine the optimal solution. The addition of KB had no significant impact on the antimicrobial efficacy of 4% NaOCl in this laboratory model.
AUSTRALIAN ENDODONTIC JOURNAL
(2023)
Review
Dentistry, Oral Surgery & Medicine
Abhishek Isaac Mathew, Silvia Lee, Willian Nguyen Ha, Venkateshbabu Nagendrababu, Giampiero Rossi-Fedele
Summary: This systematic review compared the effectiveness of polytetrafluoroethylene tape and cotton pellet as endodontic spacers, with polytetrafluoroethylene tape showing a lower incidence of microbial contamination. The evidence supporting polytetrafluoroethylene tape as a more suitable material for this purpose was consistent across both laboratory and clinical studies.
EUROPEAN ENDODONTIC JOURNAL
(2021)
Review
Veterinary Sciences
Rebecca Lee Tucker, William Nguyen Ha
Summary: This study evaluated the efficacy of MTA for VPT in permanent dog teeth, with MTA consistently performing well in calcific barrier formation and biocompatibility. Despite inconsistencies, future research could benefit from implementing standardized scoring systems and longer study durations.
JOURNAL OF VETERINARY DENTISTRY
(2021)