A Novel Acetyl-CoA Carboxylase 2 Selective Inhibitor Improves Whole-Body Insulin Resistance and Hyperglycemia in Diabetic Mice through Target-Dependent Pathways

Discovery of a novel olefin derivative as a highly potent and selective acetyl-CoA carboxylase 2 inhibitor with in vivo efficacy

(2018) Yuji Nishiura et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Development of an ultrasensitive immunoassay using affinity maturated antibodies for the measurement of rodent insulin

(2015) Sunao Imai et al.   ANALYTICAL BIOCHEMISTRY

Role of diacylglycerol activation of PKCθ in lipid-induced muscle insulin resistance in humans

(2014) Julia Szendroedi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of acetyl-CoA carboxylase 2 enhances skeletal muscle fatty acid oxidation and improves whole-body glucose homeostasis in db/db mice

(2012) S. Glund et al.   DIABETOLOGIA

Acetyl-CoA Carboxylase 2−/−Mutant Mice are Protected against Fatty Liver under High-fat, High-carbohydrate Dietary andde NovoLipogenic Conditions

(2012) Lutfi Abu-Elheiga et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acute or Chronic Upregulation of Mitochondrial Fatty Acid Oxidation Has No Net Effect on Whole-Body Energy Expenditure or Adiposity

(2010) Kyle L. Hoehn et al.   Cell Metabolism

Gene knockout of Acc2 has little effect on body weight, fat mass, or food intake

(2010) D. P. Olson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fatty acid metabolism: target for metabolic syndrome

(2008) Salih J. Wakil et al.   JOURNAL OF LIPID RESEARCH