Journal
JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
Volume 62, Issue 1, Pages E1-E6Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/JOM.0000000000001760
Keywords
asbestos; asbestosis; chest radiograph; mesothelioma; mortality
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Funding
- intramural funds of the US Department of Health and Human Services
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Objective: To evaluate mortality patterns among participants in a community-based screening program for asbestos-related disease. Methods: We calculated standardized mortality ratios (SMRs) and stratified results by exposure group (three occupational exposure groups, household contacts and residents without occupational asbestos exposure) and by radiographic abnormality presence. Results: All-cause mortality (15.8%; 1,429/8,043) was statistically lower than expected. Asbestosis was statistically elevated in all exposure groups. Lung cancer was moderately associated with vermiculite miner/miller employment. Mesothelioma was elevated in that same exposure group and among residents. Systemic autoimmune disease mortality was also elevated. Radiographic parenchymal abnormalities were associated with lung cancer mortality. Conclusion: In addition to asbestos-related mortality in occupational exposure groups, this initial follow-up of this cohort also shows elevated mortality for some asbestos-related causes in non-occupational exposure groups.
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