Management of pregestational diabetes mellitus: a comparison of guidelines

Background: Pregestational diabetes is associated with adverse maternal and neonatal outcomes. The aim of this study was to summarize and compare evidence-based recommendations on pregestational diabetes and to focus especially on issues related to the management of this entity. Materials and methods: A descriptive review of three recently published national guidelines on pregestational diabetes was conducted: the American Diabetes Association on Diabetes in Pregnancy: Standards of Medical Care in Diabetes - 2019, the National Institute for Health and Care Excellence on Diabetes in pregnancy: management from preconception to the postnatal period and the American College of Obstetricians and Gynecologists on Pregestational Diabetes Mellitus. These guidelines were compared according to recommendations on management, during the preconception, antenatal, intrapartum and postpartum period. Results: There were many similar recommendations regarding the preconception counseling, the antepartum assessment by specialists, the glycemic control target levels, the pharmacologic treatment and the postpartum period among the three guidelines. On the other hand, the American Diabetes Association makes no recommendations regarding fetal monitoring and obstetric management during pregnancy and the intrapartum period, while there are several similarities between the other two guidelines. Conclusions: The adoption of an international consensus based on evidence - based guidelines will increase the awareness of the healthcare professionals on the management of pregestational diabetes, leading that way to more favorable perinatal outcomes.

Automated summary

This study conducted a descriptive review of three recently published national guidelines on pregestational diabetes, aiming to summarize and compare evidence-based recommendations. The results showed that there were many similar recommendations among the three guidelines regarding preconception counseling, antenatal assessment, glycemic control, pharmacologic treatment, and postpartum period. However, there were some differences in recommendations on fetal monitoring and obstetric management during pregnancy and the intrapartum period.