Role of angiopoietin-like protein 3 in sugar-induced dyslipidemia in rhesus macaques: suppression by fish oil or RNAi

The association between genetic variants of angiopoietin-like 3 and risk of diabetes mellitus is modified by dietary factors in Koreans

(2019) Clara Yongjoo Park et al.   Scientific Reports

Fructose-induced hypertriglyceridemia in rhesus macaques is attenuated with fish oil or apoC3 RNA interference

(2019) Andrew A. Butler et al.   JOURNAL OF LIPID RESEARCH

Low plasma adropin concentrations increase risks of weight gain and metabolic dysregulation in response to a high-sugar diet in male nonhuman primates

(2019) Andrew A. Butler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adropin treatment restores cardiac glucose oxidation in pre-diabetic obese mice

(2019) Dharendra Thapa et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The peptide hormone adropin regulates signal transduction pathways controlling hepatic glucose metabolism in a mouse model of diet-induced obesity

(2019) Su Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adropin regulates cardiac energy metabolism and improves cardiac function and efficiency

(2019) Tariq R. Altamimi et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Apolipoprotein C-III in triglyceride-rich lipoprotein metabolism

(2018) Bastian Ramms et al.   CURRENT OPINION IN LIPIDOLOGY

Association Between Baseline LDL-C Level and Total and Cardiovascular Mortality After LDL-C Lowering

(2018) Eliano P. Navarese et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

(2018) Anubha Mahajan et al.   NATURE GENETICS

Advances in lipid-lowering therapy through gene-silencing technologies

(2018) Børge G. Nordestgaard et al.   Nature Reviews Cardiology

The complex molecular genetics of familial hypercholesterolaemia

(2018) Amanda J. Berberich et al.   Nature Reviews Cardiology

Therapeutic potential of omega-3 fatty acid-derived epoxyeicosanoids in cardiovascular and inflammatory diseases

(2018) Wolf-Hagen Schunck et al.   PHARMACOLOGY & THERAPEUTICS

Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes

(2018) Viktoria Gusarova et al.   Nature Communications

Adropin: An endocrine link between the biological clock and cholesterol homeostasis

(2018) Sarbani Ghoshal et al.   Molecular Metabolism

Association of Genetically Enhanced Lipoprotein Lipase–Mediated Lipolysis and Low-Density Lipoprotein Cholesterol–Lowering Alleles With Risk of Coronary Disease and Type 2 Diabetes

(2018) Luca A. Lotta et al.   JAMA Cardiology

Nonhuman Primates and Translational Research—Cardiovascular Disease

(2017) Laura A Cox et al.   ILAR JOURNAL

Use and Importance of Nonhuman Primates in Metabolic Disease Research: Current State of the Field

(2017) Peter J Havel et al.   ILAR JOURNAL

ANGPTL8 requires ANGPTL3 to inhibit lipoprotein lipase and plasma triglyceride clearance

(2017) Jorge F. Haller et al.   JOURNAL OF LIPID RESEARCH

Exome-wide association study of plasma lipids in >300,000 individuals

(2017) Dajiang J Liu et al.   NATURE GENETICS

Angiopoietin-like 3 in lipoprotein metabolism

(2017) Sander Kersten   Nature Reviews Endocrinology

ANGPTL3 Inhibition in Homozygous Familial Hypercholesterolemia

(2017) Daniel Gaudet et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cardiovascular and Metabolic Effects of ANGPTL3 Antisense Oligonucleotides

(2017) Mark J. Graham et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease

(2017) Frederick E. Dewey et al.   NEW ENGLAND JOURNAL OF MEDICINE

ANGPTL8 promotes the ability of ANGPTL3 to bind and inhibit lipoprotein lipase

(2017) Xun Chi et al.   Molecular Metabolism

The early years of lipoprotein research: from discovery to clinical application

(2016) Patty W. Siri-Tarino et al.   JOURNAL OF LIPID RESEARCH

Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance

(2016) Luca A Lotta et al.   NATURE GENETICS

Atherogenic Lipoprotein Subfractions Determined by Ion Mobility and First Cardiovascular Events After Random Allocation to High-Intensity Statin or PlaceboCLINICAL PERSPECTIVE

(2015) Samia Mora et al.   CIRCULATION

Hepatic ANGPTL3 regulates adipose tissue energy homeostasis

(2015) Yan Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential Responses of Plasma Adropin Concentrations To Dietary Glucose or Fructose Consumption In Humans

(2015) Andrew A. Butler et al.   Scientific Reports

Therapeutic effects of adropin on glucose tolerance and substrate utilization in diet-induced obese mice with insulin resistance

(2015) Su Gao et al.   Molecular Metabolism

Regulation of Substrate Oxidation Preferences in Muscle by the Peptide Hormone Adropin

(2014) S. Gao et al.   DIABETES

Angptl3 Deficiency Is Associated With Increased Insulin Sensitivity, Lipoprotein Lipase Activity, and Decreased Serum Free Fatty Acids

(2013) Marius R. Robciuc et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Clinical characteristics and plasma lipids in subjects with familial combined hypolipidemia: a pooled analysis

(2013) Ilenia Minicocci et al.   JOURNAL OF LIPID RESEARCH

Fish Oil Supplementation Ameliorates Fructose-Induced Hypertriglyceridemia and Insulin Resistance in Adult Male Rhesus Macaques

(2013) Andrew A. Bremer et al.   JOURNAL OF NUTRITION

The polygenic nature of hypertriglyceridaemia: implications for definition, diagnosis, and management

(2013) Robert A Hegele et al.   Lancet Diabetes & Endocrinology

Prevalence of ANGPTL3 and APOB Gene Mutations in Subjects With Combined Hypolipidemia

(2012) Davide Noto et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Inflammatory Markers and Risk of Type 2 Diabetes: A systematic review and meta-analysis

(2012) X. Wang et al.   DIABETES CARE

Low Circulating Adropin Concentrations with Obesity and Aging Correlate with Risk Factors for Metabolic Disease and Increase after Gastric Bypass Surgery in Humans

(2012) Andrew A. Butler et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Mutations in theANGPTL3Gene and Familial Combined Hypolipidemia: A Clinical and Biochemical Characterization

(2012) Ilenia Minicocci et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

C-Reactive Protein, Fibrinogen, and Cardiovascular Disease Prediction

(2012)   NEW ENGLAND JOURNAL OF MEDICINE

Adropin Deficiency Is Associated With Increased Adiposity and Insulin Resistance

(2012) K. Ganesh Kumar et al.   Obesity

Atypical angiopoietin-like protein that regulates ANGPTL3

(2012) F. Quagliarini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of Three Kindreds With Familial Combined Hypolipidemia Caused by Loss-of-Function Mutations of ANGPTL3

(2011) Livia Pisciotta et al.   Circulation-Cardiovascular Genetics

Identification of a novel mutation in the ANGPTL3 gene in two families diagnosed of familial hypobetalipoproteinemia without APOB mutation

(2011) Jesús M. Martín-Campos et al.   CLINICA CHIMICA ACTA

Fructose-Fed Rhesus Monkeys: A Nonhuman Primate Model of Insulin Resistance, Metabolic Syndrome, and Type 2 Diabetes

(2011) Andrew A. Bremer et al.   CTS-Clinical and Translational Science

Characterization of a hypertriglyceridemic transgenic miniature pig model expressing human apolipoprotein CIII

(2011) Jingyuan Wei et al.   FEBS Journal

Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170 000 participants in 26 randomised trials

(2010)   LANCET

Exome Sequencing,ANGPTL3Mutations, and Familial Combined Hypolipidemia

(2010) Kiran Musunuru et al.   NEW ENGLAND JOURNAL OF MEDICINE

Expression of apolipoprotein C-III in McA-RH7777 cells enhances VLDL assembly and secretion under lipid-rich conditions

(2009) M. Sundaram et al.   JOURNAL OF LIPID RESEARCH

siRNA and Innate Immunity

(2009) Marjorie Robbins et al.   OLIGONUCLEOTIDES

Identification of Adropin as a Secreted Factor Linking Dietary Macronutrient Intake with Energy Homeostasis and Lipid Metabolism

(2008) K. Ganesh Kumar et al.   Cell Metabolism

Direct Determination of Lipoprotein Particle Sizes and Concentrations by Ion Mobility Analysis

(2008) M. P. Caulfield et al.   CLINICAL CHEMISTRY