Nanoparticles containing β‐cyclodextrin potentially useful for the treatment of Niemann‐Pick C

Toxicological effects of transition metal-doped titanium dioxide nanoparticles on goldfish (Carassius auratus) and common carp (Cyprinus carpio)

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Monoolein-based nanoparticles for drug delivery to the central nervous system: A platform for lysosomal storage disorder treatment

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Potential adverse effects of nanoparticles on the reproductive system

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Zinc oxide nanoparticles exhibit cytotoxicity and genotoxicity through oxidative stress responses in human lung fibroblasts and Drosophila melanogaster

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Cobalt nanoparticles induce lung injury, DNA damage and mutations in mice

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Selective screening of Niemann–Pick type C Brazilian patients by cholestane-3β,5α,6β-triol and chitotriosidase measurements followed by filipin staining and NPC1/NPC2 gene analysis

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Sponge Phases and Nanoparticle Dispersions in Aqueous Mixtures of Mono- and Diglycerides

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Surviving nebulization-induced stress: dexamethasone in pH-sensitive archaeosomes

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High incidence of unrecognized visceral/neurological late-onset Niemann-Pick disease, type C1, predicted by analysis of massively parallel sequencing data sets

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Oxidative Stress and Nano-Toxicity Induced by TiO2 and ZnO on WAG Cell Line

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Metal-Based Nanoparticles and the Immune System: Activation, Inflammation, and Potential Applications

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ZnS nanoarchitectures induced dysfunction of vascular endothelial cellsin vitroandin vivo

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Nanotoxicity Overview: Nano-Threat to Susceptible Populations

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Complex lipid trafficking in Niemann-Pick disease type C

(2014) Marie T. Vanier   JOURNAL OF INHERITED METABOLIC DISEASE

Niemann-Pick C disease and mobilization of lysosomal cholesterol by cyclodextrin

(2014) Jean E. Vance et al.   JOURNAL OF LIPID RESEARCH

Cyclodextrin alleviates neuronal storage of cholesterol in Niemann-Pick C disease without evidence of detectable blood–brain barrier permeability

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Self-Assembly of Nonionic Surfactant Tween 20@2β-CD Inclusion Complexes in Dilute Solution

(2013) Chengcheng Zhou et al.   LANGMUIR

DNA Damage Caused by Metal Nanoparticles: Involvement of Oxidative Stress and Activation of ATM

(2012) Rong Wan et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Nanoparticles: a review of particle toxicology following inhalation exposure

(2012) Shahnaz Bakand et al.   INHALATION TOXICOLOGY

Mechanism of polymeric nanoparticle-based drug transport across the blood-brain barrier (BBB)

(2012) Jörg Kreuter   JOURNAL OF MICROENCAPSULATION

Uptake Mechanism of ApoE-Modified Nanoparticles on Brain Capillary Endothelial Cells as a Blood-Brain Barrier Model

(2012) Sylvia Wagner et al.   PLoS One

Susceptibility to gold nanoparticle-induced hepatotoxicity is enhanced in a mouse model of nonalcoholic steatohepatitis

(2012) Jung Hwan Hwang et al.   TOXICOLOGY

Mitochondrial membrane potential probes and the proton gradient: a practical usage guide

(2011) Seth W. Perry et al.   BIOTECHNIQUES

A sensitive and specific LC-MS/MS method for rapid diagnosis of Niemann-Pick C1 disease from human plasma

(2011) Xuntian Jiang et al.   JOURNAL OF LIPID RESEARCH

Functionalized nanosystems for targeted mitochondrial delivery

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Mechanistic Toxicity Assessment of Nanomaterials by Whole-Cell-Array Stress Genes Expression Analysis

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Niemann-Pick disease type C

(2010) Marie T Vanier   Orphanet Journal of Rare Diseases

2-Hydroxypropyl-β-Cyclodextrin Raises Hearing Threshold in Normal Cats and in Cats With Niemann-Pick Type C Disease

(2010) Sarah Ward et al.   PEDIATRIC RESEARCH

Weekly Cyclodextrin Administration Normalizes Cholesterol Metabolism in Nearly Every Organ of the Niemann-Pick Type C1 Mouse and Markedly Prolongs Life

(2010) Charina M Ramirez et al.   PEDIATRIC RESEARCH

Drug delivery to the brain using surfactant-coated poly(lactide-co-glycolide) nanoparticles: Influence of the formulation parameters

(2009) Svetlana Gelperina et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Albumin nanoparticles targeted with Apo E enter the CNS by transcytosis and are delivered to neurones

(2009) Anja Zensi et al.   JOURNAL OF CONTROLLED RELEASE

Chronic Cyclodextrin Treatment of Murine Niemann-Pick C Disease Ameliorates Neuronal Cholesterol and Glycosphingolipid Storage and Disease Progression

(2009) Cristin D. Davidson et al.   PLoS One

Cyclodextrin overcomes deficient lysosome-to-endoplasmic reticulum transport of cholesterol in Niemann-Pick type C cells

(2009) L. Abi-Mosleh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neutral red uptake assay for the estimation of cell viability/cytotoxicity

(2008) Guillermo Repetto et al.   Nature Protocols

Cytotoxicity of Nanoparticles

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