The Japanese Encephalitis Virus NS1′ Protein Inhibits Type I IFN Production by Targeting MAVS

Flavivirus NS1 Triggers Tissue-Specific Vascular Endothelial Dysfunction Reflecting Disease Tropism

(2019) Henry Puerta-Guardo et al.   Cell Reports

Hepatovirus 3ABC proteases and evolution of mitochondrial antiviral signaling protein (MAVS)

(2019) Hui Feng et al.   JOURNAL OF HEPATOLOGY

Regulation of MAVS activation through post-translational modifications

(2018) Bingyu Liu et al.   CURRENT OPINION IN IMMUNOLOGY

Japanese encephalitis — the prospects for new treatments

(2018) Lance Turtle et al.   Nature Reviews Neurology

Zika Virus Non-structural Protein 4A Blocks the RLR-MAVS Signaling

(2018) Jinzhu Ma et al.   Frontiers in Microbiology

Structural variability in the RLR-MAVS pathway and sensitive detection of viral RNAs

(2018) Qiu-Xing Jiang   Medicinal Chemistry

Japanese Encephalitis Virus NS1′ Protein Antagonizes Interferon Beta Production

(2018) Dengyuan Zhou et al.   VIROLOGICA SINICA

West Nile Virus NS1 Antagonizes Interferon Beta Production by Targeting RIG-I and MDA5

(2017) Hong-Lei Zhang et al.   JOURNAL OF VIROLOGY

NLRX1 Mediates MAVS Degradation To Attenuate the Hepatitis C Virus-Induced Innate Immune Response through PCBP2

(2017) Yuwen Qin et al.   JOURNAL OF VIROLOGY

Japanese Encephalitis Virus NS5 Inhibits Type I Interferon (IFN) Production by Blocking the Nuclear Translocation of IFN Regulatory Factor 3 and NF-κB

(2017) Jing Ye et al.   JOURNAL OF VIROLOGY

iRhom2 is essential for innate immunity to RNA virus by antagonizing ER- and mitochondria-associated degradation of VISA

(2017) Wei-Wei Luo et al.   PLoS Pathogens

Microarray Analysis Identifies the Potential Role of Long Non-Coding RNA in Regulating Neuroinflammation during Japanese Encephalitis Virus Infection

(2017) Yunchuan Li et al.   Frontiers in Immunology

Pathogen-associated molecular patterns activate expression of genes involved in cell proliferation, immunity and detoxification in the amebocyte-producing organ of the snail Biomphalaria glabrata

(2016) Si-Ming Zhang et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Duck Tembusu Virus Nonstructural Protein 1 Antagonizes IFN-β Signaling Pathways by Targeting VISA

(2016) Junyong Wang et al.   JOURNAL OF IMMUNOLOGY

MicroRNA-19b-3p Modulates Japanese Encephalitis Virus-Mediated Inflammation via Targeting RNF11

(2016) Usama Ashraf et al.   JOURNAL OF VIROLOGY

MicroRNA-33a-5p Modulates Japanese Encephalitis Virus Replication by Targeting Eukaryotic Translation Elongation Factor 1A1

(2016) Zheng Chen et al.   JOURNAL OF VIROLOGY

Dengue Virus Subverts Host Innate Immunity by Targeting Adaptor Protein MAVS

(2016) Zhenjian He et al.   JOURNAL OF VIROLOGY

MicroRNA-22 negatively regulates poly(I:C)-triggered type I interferon and inflammatory cytokine production via targeting mitochondrial antiviral signaling protein (MAVS)

(2016) Shengfeng Wan et al.   Oncotarget

miR-206 modulates lipopolysaccharide-mediated inflammatory cytokine production in human astrocytes

(2015) Xiaodong Duan et al.   CELLULAR SIGNALLING

The A66G back mutation in NS2A of JEV SA 14 -14-2 strain contributes to production of NS1′ protein and the secreted NS1′ can be used for diagnostic biomarker for virulent virus infection

(2015) Jingman Wang et al.   INFECTION GENETICS AND EVOLUTION

Last 20 aa of the West Nile virus NS1′ protein are responsible for its retention in cells and the formation of unique heat-stable dimers

(2015) Lucy B. Young et al.   JOURNAL OF GENERAL VIROLOGY

MicroRNA-15b Modulates Japanese Encephalitis Virus–Mediated Inflammation via Targeting RNF125

(2015) Bibo Zhu et al.   JOURNAL OF IMMUNOLOGY

Dengue Virus NS Proteins Inhibit RIG-I/MAVS Signaling by Blocking TBK1/IRF3 Phosphorylation: Dengue Virus Serotype 1 NS4A Is a Unique Interferon-Regulating Virulence Determinant

(2015) Nadine A. Dalrymple et al.   mBio

Porcine Epidemic Diarrhea Virus Nucleocapsid Protein Antagonizes Beta Interferon Production by Sequestering the Interaction between IRF3 and TBK1

(2014) Z. Ding et al.   JOURNAL OF VIROLOGY

Pattern Recognition and Signaling Mechanisms of RIG-I and MDA5

(2014) Stephanie Reikine et al.   Frontiers in Immunology

Dengue Virus Subverts the Interferon Induction Pathway via NS2B/3 Protease-IκB Kinase ε Interaction

(2013) Yesseinia I. Angleró-Rodríguez et al.   Clinical and Vaccine Immunology

Herpes Simplex Virus 1 Ubiquitin-Specific Protease UL36 Inhibits Beta Interferon Production by Deubiquitinating TRAF3

(2013) S. Wang et al.   JOURNAL OF VIROLOGY

NS1' Colocalizes with NS1 and Can Substitute for NS1 in West Nile Virus Replication

(2013) L. B. Young et al.   JOURNAL OF VIROLOGY

The Essential, Nonredundant Roles of RIG-I and MDA5 in Detecting and Controlling West Nile Virus Infection

(2013) J. S. Errett et al.   JOURNAL OF VIROLOGY

Gig1, a novel antiviral effector involved in fish interferon response

(2013) Fan Sun et al.   VIROLOGY

Japanese encephalitis

(2013) Sang-Im Yun et al.   Human Vaccines & Immunotherapeutics

Novel Therapeutic Approaches in Limiting Oxidative Stress and Inflammation

(2012) Agnieszka Spychalowicz et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

A single nucleotide mutation in NS2A of Japanese encephalitis-live vaccine virus (SA14-14-2) ablates NS1' formation and contributes to attenuation

(2012) Q. Ye et al.   JOURNAL OF GENERAL VIROLOGY

ISG56 and IFITM1 Proteins Inhibit Hepatitis C Virus Replication

(2011) A. Raychoudhuri et al.   JOURNAL OF VIROLOGY

IPS-1 Is Essential for the Control of West Nile Virus Infection and Immunity

(2010) Mehul S. Suthar et al.   PLoS Pathogens

A central role for RNA in the induction and biological activities of type 1 interferons

(2010) Xiao-Ling Li et al.   Wiley Interdisciplinary Reviews-RNA

NS1' of Flaviviruses in the Japanese Encephalitis Virus Serogroup Is a Product of Ribosomal Frameshifting and Plays a Role in Viral Neuroinvasiveness

(2009) E. B. Melian et al.   JOURNAL OF VIROLOGY

A conserved predicted pseudoknot in the NS2A-encoding sequence of West Nile and Japanese encephalitis flaviviruses suggests NS1' may derive from ribosomal frameshifting

(2009) Andrew E Firth et al.   Virology Journal

West Nile Virus Nonstructural Protein 1 Inhibits TLR3 Signal Transduction

(2008) J. R. Wilson et al.   JOURNAL OF VIROLOGY