Article
Surgery
Jemma Mytton, Prita Daliya, Pritam Singh, Simon L. Parsons, Dileep N. Lobo, Richard Lilford, Ravinder S. Vohra
Summary: Over 50% of patients in England did not undergo cholecystectomy following index admission for acute cholecystitis. Mortality was higher in the nonoperated group, which was mostly due to non-gallbladder pathologies but total hospital admission time for biliary causes was lower over 12 months.
Article
Surgery
Hassan M. Albisher, Mohammed S. Foula, Elham S. Alghusnah, Tarig Abdelha
Summary: This study examines the risk factors and outcome of acute and subacute gallbladder perforation (AGBP) in a tertiary hospital in Saudi Arabia. The results showed that AGBP is more common in elderly male patients with multiple comorbidities. Laparoscopic cholecystectomy is a safe management approach.
ASIAN JOURNAL OF SURGERY
(2023)
Article
Medicine, General & Internal
Huan Wang, Emilie Lambourg, Bruce Guthrie, Daniel R. Morales, Peter T. Donnan, Samira Bell
Summary: This study highlights the importance of early recognition and management of AKI in order to prevent progression to AKD and long-term adverse outcomes.
Article
Clinical Neurology
Lotte Sahin Levison, Reimar Wernich Thomsen, Henning Andersen
Summary: The study found that within 6 months of GBS hospital admission, the mortality rate was 6.6 times higher compared to the general population of the same age. The mortality rate continued to increase for approximately 4 years following GBS, and then leveled off to a similar long-term mortality rate.
EUROPEAN JOURNAL OF NEUROLOGY
(2022)
Article
Gastroenterology & Hepatology
Chris Varghese, Matthew McGuinness, Cameron I. Wells, Brodie M. Elliott, Ashok Gunawardene, Melissa Edwards, Ravinder Vohra, Ewen A. Griffiths, Saxon Connor, Garth H. Poole, John A. Windsor, Deborah Wright, Christopher Harmston, Jim Hsu-Shun Wang, John Windsor, Elizabeth Chen, Kaustubha Ghate, Shayal Lal, Binura Lekamalage, Milidu Ratnayake, Arpita Bansal, John Windsor, Seagh von Keisenberg, Arthana Hemachandran, Megan Singhal, Nejo Joseph, Sameer Bhat, Jeremy Rossaak, Daniel Carson, Nandini Dubey, Marcus Pan, Liam Ferguson, Imogen Watt, Jenny Choi, Jared Mclauchlan, Saxon Connor, Ella Nicholas, Ibrahim Al-Busaidi, Douglas Wood, Cheyaanthan Haran, Anthony Lin, Paul Fagan, Andrea Bathgate, Saloni Patel, Josephine Mak, Emma Espiner, Garth Poole, Summer Hassan, Zunaira Javed, Madi Randall, Sydney Clough, William Cook, Sita Clark, Carys Finlayson, Garth Poole, Praharsh Bahl, Surya Singh, Cindy Lin, Clair Wang, Reina Kittaka, Mathew Morreau, Andrew Ing, Sarah Logan, Sam Guest, Kirsty Sutherland, Alex Lewis, Jessica Roberts, Bridget Watson, James Tietjens, Rebecca Teague, Bruce Su'a, Anupam Modi, Varun Modi, Yahaira Williams, Jonty Morreau, Choo Khoo, Brendan Desmond, Michael Young, Renee Christmas, Teresa Holm, Christopher Harmston, Kieran Long, Briar Garton, Niki Kau, Lucy Barber, Mostafa Amer, James Haddow, Mostafa Amer, Chekodi Fearnley-Fitzgerald, Karen Suresh, Edwin Zeng, Anastasia Young-Gough, Jordan Skeet, Falah El-Haddawi, Matias Alvarez, Son Nguyen, Jasmin King, James Crichton, Fraser Welsh, Melissa Edwards, Jeffrey Tan, Jonathon Luo, Karankumar Banker, Xavier Field, Philip Allan, Sarah Rennie, Chathura Bathiya Ratnayake, Sanket Srinivasa, Jee Hyun Gloria Kim, Sarah Bradley, Nivedita Singh, Grace Kang, William Xu, Sanket Srinivasa, Holly Cook, Vyoma Mistry, Kaavya Dabla, Abraham Montes de Oca, Vithushiya Yoganandarajah, Marianne Lill, Jacky Lu, Louis Antoine Bonnet, Thitapon Uiyapat
Summary: This study investigated the practice of cholecystectomy in New Zealand and found significant variations in the rates of index and elective cholecystectomy. These variations were not adequately explained by patient, operative, or hospital factors alone. Therefore, national quality improvement efforts are needed to standardise the availability of cholecystectomy.
Article
Medicine, General & Internal
Kevin Sheng-Kai Ma, Chee-Ming Lee, Po-Hung Chen, Yan Yang, Yi Wei Dong, Yu-Hsun Wang, James Cheng-Chung Wei, Wen Jie Zheng
Summary: This study found that patients with optic neuritis have a higher risk of developing autoimmune diseases, especially those who are young or female. The use of corticosteroids reduced the link between optic neuritis and subsequent autoimmune diseases.
FRONTIERS IN MEDICINE
(2022)
Article
Medicine, General & Internal
Yanfang Guo, Malia S. Q. Murphy, Erica Erwin, Romina Fakhraei, Daniel J. Corsi, Ruth Rennicks White, Alysha L. J. Harvey, Laura M. Gaudet, Mark C. Walker, Shi Wu Wen, Darine El-Chaar
Summary: The study investigated the trends, determinants, and outcomes of cesarean delivery on maternal request (CDMR) and found that the prevalence of CDMR remained stable, with women planning CDMR having a lower risk of adverse outcomes compared to those planning vaginal delivery. Further investigation into the long-term implications of CDMR is warranted.
CANADIAN MEDICAL ASSOCIATION JOURNAL
(2021)
Article
Gastroenterology & Hepatology
Roberto Candia, Macarena Vinuela, Javier Chahuan, Luis A. Diaz, Vicente Gandara, Pedro Errazuriz, Luis Bustamante, Alejandro Villalon, Alvaro Huete, Fernando Crovari, Eduardo Briceno
Summary: Gallbladder polyps in a high-risk Hispanic population appear to have a low risk of neoplasia, with polyp size and number being the main factors associated with neoplasia.
Article
Dentistry, Oral Surgery & Medicine
K. S. Ma, H. Hasturk, I Carreras, A. Dedeoglu, J. J. Veeravalli, J. Y. Huang, A. Kantarci, J. C. Wei
Summary: Patients with dementia and AD have a significantly higher risk of PD, which is age-dependent and independent of systemic confounding factors.
JOURNAL OF DENTAL RESEARCH
(2022)
Article
Clinical Neurology
Min Xu, Adriana Amarilla Vallejo, Clara Cantalapiedra Calvet, Anthony Rudd, Charles Wolfe, Matthew D. L. O'Connell, Abdel Douiri
Summary: Female stroke patients have lower adjusted risk of death and stroke recurrence or death compared to male patients. However, they have poorer outcomes in terms of activities of daily living, anxiety, and health-related quality of life, which persist up to 5 years after stroke.
Article
Endocrinology & Metabolism
Eun Ji Lee, Cheol Min Shin, Dong Ho Lee, Kyungdo Han, Sang Hyun Park, Yoo Jin Kim, Hyuk Yoon, Young Soo Park, Nayoung Kim
Summary: Individuals who underwent cholecystectomy have an increased risk of fractures, especially vertebral and hip fractures. The risk of vertebral fractures following cholecystectomy is more prominent in the younger population.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Public, Environmental & Occupational Health
Runmin Lai, Ruiqi Li, Tong Wang, Jianqing Ju, Qiyu Liu, Jie Zhang, Luxia Song, Hao Xu
Summary: This study examines the effect of short-term socioeconomic status (SES) shift on long-term cardiovascular outcomes in China. The results suggest that an improvement in SES is associated with better cardiovascular outcomes in the long term.
JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH
(2022)
Article
Medicine, General & Internal
Ji Young Chang, Hye-Kyung Jung, Chang Mo Moon, Seong-Eun Kim, Ki-Nam Shim, Sung-Ae Jung, Seog Ki Min
Summary: The study found that there is an overlap of FGID symptoms in patients with symptomatic cholelithiasis before and after cholecystectomy. Additionally, new-onset FGIDs may occur after cholecystectomy. Therefore, delicate diagnostic approaches and appropriate treatments for co-existent FGIDs should be given in patients with cholelithiasis before and after cholecystectomy.
FRONTIERS IN MEDICINE
(2023)
Article
Oncology
Julian Wang, Pablo E. Serrano, Christopher Griffiths, Sameer Parpia, Marko Simunovic
Summary: The greater use of MILR for colorectal cancer liver metastases was associated with a 1-day shorter length of hospital stay. Surgeon enthusiasm for MILR among a small number of opinion leaders likely influenced the uptake of this complex innovation.
ANNALS OF SURGICAL ONCOLOGY
(2021)
Article
Surgery
Michael J. Horkoff, Zubir Ahmed, Yuan Xu, Francis R. Sutherland, Elijah Dixon, Chad G. Ball, Oliver F. Bathe
Summary: A retrospective cohort comparison study on incidentally discovered gallbladder cancer cases showed that bile spillage during cholecystectomy has adverse effects on patient outcomes, leading to higher incidence of peritoneal carcinomatosis, lower likelihood of radical re-resection, and shorter disease-free survival.
Article
Surgery
Kerry N. L. Avery, Nicholas Wilson, Rhiannon Macefield, Angus McNair, Christin Hoffmann, Jane M. Blazeby, Shelley Potter
Summary: This study aims to develop a COS, an agreed minimum set of outcomes to measure and report in studies evaluating novel surgical techniques. Currently, there is a lack of agreement on key outcomes for safe and efficient surgical innovation. The study generated a list of outcome domains, prioritized them through a Delphi survey, and reached consensus through a meeting involving international stakeholders.
Correction
Medicine, General & Internal
Dave Moore, Lucy Burns, Ben Creavin, Eanna Ryan, Kevin Conlon, Michael Eamon Kelly, Dara Oliver Kavanagh
IRISH JOURNAL OF MEDICAL SCIENCE
(2023)
Review
Clinical Neurology
Syed Uzair Ahmed, Xiongbiao Chen, Lissa Peeling, Michael E. Kelly
Summary: The advent of endovascular therapy has revolutionized stroke treatment, with stentrievers being a mainstay in this field. This article discusses the technical requirements, design variables, and clinical data of stentrievers, as well as the ongoing development and testing in this area.
INTERVENTIONAL NEURORADIOLOGY
(2023)
Article
Clinical Neurology
James J. M. Loan, Steven Tominey, Kirun Baweja, Julie Woodfield, Thomas J. G. Chambers, Mark Haley, Simran S. Kundu, H. Y. Josephine Tang, Anthony N. Wiggins, Michael T. C. Poon, Paul M. Brennan
Summary: In this comprehensive multicentre prospective-adjusted analysis of patients with SAH, the screening, investigation, and management of hyponatraemia were found to be inconsistent and not associated with changes in management or clinical outcomes for most patients.
STROKE AND VASCULAR NEUROLOGY
(2023)
Review
Oncology
Conor Aylward, Jawed Noori, Jack Tyrrell, Niall O'sullivan, Dara O. Kavanagh, John O. Larkin, Brian J. Mehigan, Paul H. McCormick, Michael E. Kelly
Summary: There is a lack of consensus on the management of colorectal cancer with synchronous para-aortic lymph node metastasis (PALNM), and retrospective data suggests a potential benefit in highly selective cohorts, requiring a case-by-case evaluation.
JOURNAL OF SURGICAL ONCOLOGY
(2023)
Review
Cell Biology
Luca Cristin, Amalia Montini, Alessandro Martinino, Juan Pablo Scarano Pereira, Francesco Giovinazzo, Salvatore Agnes
Summary: Diabetic and obese patients are highly likely to have non-alcoholic fatty liver disease (NAFLD). Growth hormone (GH) and insulin-like growth factor 1 (IGF-1) play important roles in the development of NAFLD and could be used as therapeutic strategies to prevent NAFLD progression to non-alcoholic steatohepatitis (NASH).
Article
Gastroenterology & Hepatology
Robert Walker, Andrew Currie, Tom Wiggins, Sheraz R. Markar, Natalie S. Blencowe, Tim Underwood, Marianne Hollyman
Summary: Gastro-esophageal reflux disease (GERD) is a common health burden. There is a lack of consensus on patient selection for surgery and optimal surgical technique. More information on the delivery of anti-reflux surgery (ARS) is needed.
DISEASES OF THE ESOPHAGUS
(2023)
Letter
Gastroenterology & Hepatology
Abdul Rahman Hakeem, Rhiannon Taylor, Raj Prasad
JOURNAL OF HEPATOLOGY
(2023)
Article
Gastroenterology & Hepatology
Naima Endesh, Eulashini Chuntharpursat-Bon, Charlotte Revill, Nadira Y. Yuldasheva, T. Simon Futers, Gregory Parsonage, Neil Humphreys, Antony Adamson, Lara C. Morley, Richard M. Cubbon, K. Raj Prasad, Richard Foster, Laeticia Lichtenstein, David J. Beech
Summary: The study aimed to determine the relevance and relationship of PIEZO1 and TRPV4 channels in the contractile tone of the hepatic portal vein, which experiences mechanical and osmotic variations as it delivers blood to the liver. Results showed that activation of PIEZO1 leads to vessel relaxation while activation of TRPV4 causes contraction. The modulation of these channels could provide important opportunities for manipulating liver perfusion and regeneration.
LIVER INTERNATIONAL
(2023)
Article
Medicine, Research & Experimental
Mark R. Edwards, Gordon Forbes, Neil Walker, Dion G. Morton, Monty G. Mythen, Dave Murray, Iain Anderson, Borislava Mihaylova, Ann Thomson, Matt Taylor, Marianne Hollyman, Rachel Phillips, Keith Young, Brennan C. Kahan, Rupert M. Pearse, Michael P. W. Grocott
Summary: This study aims to investigate the effectiveness of perioperative cardiac output-guided haemodynamic therapy in reducing complications and mortality in patients undergoing major emergency gastrointestinal surgery. It is the largest contemporary randomised trial in this field and utilizes a multi-center design and broad inclusion criteria, ensuring its external validity. The primary outcome measure is the number of days alive and out of hospital within 90 days of randomization. The importance rating for this study is 9 out of 10.
Editorial Material
Critical Care Medicine
David N. Naumann, Tom Barker
Summary: There have been sporadic reports of 'traumatic appendicitis' for almost a century, but the occurrence of acute appendicitis following injury may be coincidental rather than causative. To illustrate this statistical phenomenon, a computer simulation of traumatic appendicitis in the UK population showed that there were enough cases every 2-3 years to account for the entire global literature on the topic. Therefore, further case reports of traumatic appendicitis should provide robust justification and evidence of a credible pathological process with demonstrable causality.
TRAUMA SURGERY & ACUTE CARE OPEN
(2023)
Article
Public, Environmental & Occupational Health
J. Houdmont, P. Daliya, A. Adiamah, E. Theophilidou, J. Hassard, D. N. Lobo
Summary: Surgeons' psychosocial working conditions were poor and associated with burnout. Risk management activities based on management standards can help reduce burnout among surgeons.
OCCUPATIONAL MEDICINE-OXFORD
(2023)
Review
Emergency Medicine
Federico Coccolini, Massimo Sartelli, Robert Sawyer, Kemal Rasa, Bruno Viaggi, Fikri Abu-Zidan, Kjetil Soreide, Timothy Hardcastle, Deepak Gupta, Cino Bendinelli, Marco Ceresoli, Vishal G. G. Shelat, Richard ten Broek, Gian Luca Baiocchi, Ernest E. E. Moore, Ibrahima Sall, Mauro Podda, Luigi Bonavina, Igor A. A. Kryvoruchko, Philip Stahel, Kenji Inaba, Philippe Montravers, Boris Sakakushev, Gabriele Sganga, Paolo Ballestracci, Manu L. N. G. Malbrain, Jean-Louis Vincent, Manos Pikoulis, Solomon Gurmu Beka, Krstina Doklestic, Massimo Chiarugi, Marco Falcone, Elena Bignami, Viktor Reva, Zaza Demetrashvili, Salomone Di Saverio, Matti Tolonen, Pradeep Navsaria, Miklosh Bala, Zsolt Balogh, Andrey Litvin, Andreas Hecker, Imtiaz Wani, Andreas Fette, Belinda De Simone, Rao Ivatury, Edoardo Picetti, Vladimir Khokha, Edward Tan, Chad Ball, Carlo Tascini, Yunfeng Cui, Raul Coimbra, Michael Kelly, Costanza Martino, Vanni Agnoletti, Marja A. A. Boermeester, Nicola De'Angelis, Mircea Chirica, Walt L. L. Biffl, Luca Ansaloni, Yoram Kluger, Fausto Catena, Andrew W. W. Kirkpatrick
Summary: Intra-abdominal infections are a common global healthcare challenge caused by disruption to the gastrointestinal tract. It requires intensive resource utilization and physical source control is often needed. Advances have been made in non-surgical interventional procedures and open abdomen techniques to aid source control. The concept and adequacy of source control in intra-abdominal infections need a multidisciplinary approach.
WORLD JOURNAL OF EMERGENCY SURGERY
(2023)
Review
Surgery
Cleo Kenington, Hannah Javanmard-Emamghissi, Muhammad Rafaih Iqbal, Nauman Ahmed, Chandima Halahakoon, Gareth Bashir, Sonia Lockwood, Kara Dent, Chris Elton, Salaish Mischra, Kamal Mahawar
BRITISH JOURNAL OF SURGERY
(2023)
Review
Surgery
Marc M. Huttman, Harry F. Robertson, Alexander N. Smith, Sarah E. Biggs, Ffion Dewi, Lauren K. Dixon, Emily N. Kirkham, Conor S. Jones, Jozel Ramirez, Darren L. Scroggie, Benjamin E. Zucker, Samir Pathak, Natalie S. Blencowe
Summary: This study evaluated the extent to which robot-assisted anti-reflux surgery (RA-ARS) has followed the IDEAL framework during its evolution. The results showed variability in the reporting standards of RA-ARS studies, with under-reporting of important aspects of study design and a high degree of outcome heterogeneity. Further well-designed prospective studies and randomized trials are needed, along with agreement on outcome selection, measurement, and reporting for future RA-ARS studies.
JOURNAL OF ROBOTIC SURGERY
(2023)
