Article
Multidisciplinary Sciences
Mingxuan Li, Haixia Tu, Yu Yan, Zhen Guo, Haitao Zhu, Jiangliang Niu, Mengchen Yin
Summary: This study conducted a meta-analysis to compare the efficacy of drug-eluting stent (DES) and bare metal stent (BMS) for treating femoropopliteal artery diseases (FPADs). The results showed that DES did not demonstrate superiority or inferiority to BMS in maintaining primary patency, avoiding in-stent restenosis, and target lesion revascularization.
Article
Peripheral Vascular Disease
Ahmed A. Naiem, Robert James Doonan, Oren K. Steinmetz, Kent S. MacKenzie, Elie Girsowicz, Jason P. Bayne, Daniel Obrand, Heather L. Gill
Summary: The study evaluated the outcomes of endovascular treatment in patients with moderate and severe claudication due to femoropopliteal disease, showing that careful patient selection is important for planning such treatment. It could result in symptomatic improvement in more than half of the patients, with adverse outcomes such as major adverse limb events, progression to CLTI, and amputations occurring at low rates.
Article
Cardiac & Cardiovascular Systems
David Koeckerling, Peter Francis Raguindin, Lum Kastrati, Sarah Bernhard, Joseph Barker, Andrea Carolina Quiroga Centeno, Hamidreza Raeisi-Dehkordi, Farnaz Khatami, Christa Niehot, Anne Lejay, Zoltan Szeberin, Christian-Alexander Behrendt, Joakim Nordanstig, Taulant Muka, Iris Baumgartner
Summary: This systematic review and meta-analysis compared the efficacy and safety outcomes of different endovascular approaches in patients with intermittent claudication. The results showed that drug-coated balloons had better primary patency and lower target-lesion revascularization rates compared to balloon angioplasty in both short-term and long-term follow-up. However, the efficacy of other treatment methods remains uncertain.
EUROPEAN HEART JOURNAL
(2023)
Article
Surgery
Anne G. L. Aaij, Bryan Wermelink, Marieke Haalboom, Anco C. Vahl, Robbert Meerwaldt, Robert H. Geelkerken
Summary: Compliance with the guidelines for supervised exercise therapy among patients with intermittent claudication in a large teaching hospital in the Netherlands was 80.5%. Deviation from the guidelines was found in 19.5% of patients, with almost three quarters of this deviation being attributed to the decision to provide personalized, meaningful care.
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
(2021)
Article
Surgery
Mark J. W. Koelemay, Nick S. van Reijen, Susan van Dieren, Franceline A. Frans, Erik J. G. Vermeulen, Hessel C. J. L. Buscher, Jim A. Reekers
Summary: International guidelines recommend supervised exercise therapy (SET) as primary treatment for intermittent claudication (IC), but endovascular revascularisation (ER) might be more effective for patients with iliac artery obstruction. This study found that both SET and ER improve maximum walking distance on a treadmill (MWD) and disease specific quality of life for IC patients caused by iliac artery obstruction. Therefore, starting with SET and accepting a certain failure rate seems to be a reasonable strategy for these patients.
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
(2022)
Review
Surgery
Guy Martin, Marco Covani, Fadi Saab, Jihad Mustapha, Martin Malina, Lorenzo Patrone
Summary: The ipsilateral retrograde approach to femoropopliteal lesions demonstrates good primary technical success and a low rate of complications, making it a promising bailout or primary access technique for complex lesions. However, further research is needed to identify the optimal technique and patient population that would benefit most from this approach.
JOURNAL OF VASCULAR SURGERY
(2021)
Article
Surgery
Leigh Ann O'Banion, Samer Saadi, Bashar Hasan, Tarek Nayfeh, Jessica P. Simons, Mohammad H. Murad, Karen Woo
Summary: This study reviewed the systematic review research on the treatment of intermittent claudication and identified evidence gaps. There are important gaps in the evaluation of this disease, especially in the assessment of patient-reported outcomes and standardized measures of walking distance.
JOURNAL OF VASCULAR SURGERY
(2023)
Article
Surgery
Grzegorz Halena, Dainis K. Krievins, Dierk Scheinert, Janis Savlovskis, Piotr Szopinski, Albrecht Kramer, Kenneth Ouriel, Andrej Schmidt, Michal Zdunek, Sean P. Lyden
Summary: The study investigated the 2-year safety and effectiveness of the percutaneous femoropopliteal bypass using the PQ Bypass DETOUR system. Results showed favorable outcomes for patients with long, severely calcified, or occluded femoropopliteal lesions over the 2-year follow-up period.
JOURNAL OF ENDOVASCULAR THERAPY
(2022)
Article
Hematology
Mengfei Yi, Jianjun Guo, Yanxia Gao, Jianzhuang Ren, Yonghua Bi, Xinwei Han
Summary: For patients with chronic femoropopliteal occlusive disease, catheter-directed thrombolysis (CDT) is a safe and cost-effective strategy, with no significant differences observed in clinical outcomes compared to conventional treatments.
CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS
(2021)
Article
Cardiac & Cardiovascular Systems
S. Elissa Altin, Helen Parise, Connie N. Hess, Ning A. Rosenthal, Mark A. Creager, Herbert D. Aronow, Jeptha P. Curtis
Summary: This study evaluated the rates of revascularization and amputation after lower extremity femoropopliteal peripheral vascular intervention (PVI) in patients with intermittent claudication (IC). The 4-year amputation rate following FP PVI was 4.3%, with a major amputation rate of 3.2%. Further investigation is needed to identify risk factors for amputation.
JACC-CARDIOVASCULAR INTERVENTIONS
(2023)
Article
Peripheral Vascular Disease
Mitsuyoshi Takahara, Yoshimitsu Soga, Masahiko Fujihara, Daizo Kawasaki, Amane Kozuki, Osamu Iida
Summary: This study aimed to investigate the mortality risk in patients undergoing femoropopliteal endovascular therapy for intermittent claudication, and found that the risk increased with age. However, the risk ratio relative to the matched citizens decreased with age. Younger patients had a higher mortality risk relative to the matched citizens, while patients aged >_ 85 years had a lower mortality risk relative to the matched citizens.
JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS
(2022)
Article
Surgery
Nick S. van Reijen, Susan van Dieren, Franceline A. Frans, Jim A. Reekers, Roderik Metz, Hessel C. J. L. Buscher, Mark J. W. Koelemay
Summary: This study compares the cost effectiveness of endovascular revascularisation (ER) and supervised exercise therapy (SET) as primary treatment for patients with intermittent claudication (IC) due to iliac artery obstruction. The results show that ER as a primary treatment results in slightly better health outcomes, QALYs, and HRQOL during 12 months of follow up compared to SET. However, the clinical relevance of these differences needs to be further discussed due to the small differences and relatively high cost of ER.
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
(2022)
Article
Cardiac & Cardiovascular Systems
Yu-Ping Zhou, Yun-Peng Wei, Yin-Jian Yang, Xi-Qi Xu, Tao Wu, Chao Liu, Ke-Yi Mei, Fu-Hua Peng, Hai-Ping Wang, Kai Sun, Jing-Yi Li, Hui-Fang Wang, Meng-Tao Li, Duo-Lao Wang, Qi Miao, Xin Jiang, Zhi-Cheng Jing
Summary: This study investigated the efficacy and safety of percutaneous transluminal pulmonary angioplasty (PTPA) for Takayasu arteritis-associated pulmonary hypertension (TA-PH). The results showed that PTPA was associated with a reduced risk of all-cause mortality in TA-PH patients and had acceptable safety profiles, suggesting it as a promising therapeutic option.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Article
Surgery
Henrik Bergenfeldt, Hans Lindgren, Tobias Kuhme
Summary: This case report discusses the development of pseudoaneurysms after endovascular recanalization of an occluded venous femoropopliteal bypass graft, potentially attributed to impaired vessel wall healing following intraluminal paclitaxel administration. It sheds light on considerations for treating occluded venous femoropopliteal bypass grafts.
ANNALS OF VASCULAR SURGERY
(2021)
Article
Surgery
Aluisio Andrade-Lima, Natan Silva Junior, Marcel Chehuen, Roberto Miyasato, Rodrigo W. A. Souza, Anthony S. Leicht, Patricia C. Brum, Edilamar M. de Oliveira, Nelson Wolosker, Claudia L. M. Forjaz
Summary: The study found that submaximal walking training can improve nitric oxide bioavailability, reduce systemic and local oxidative stress and inflammation in patients with intermittent claudication. The proposed training protocol may contribute to cardiovascular health improvement in these patients.
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
(2021)
Article
Peripheral Vascular Disease
Said Ibeggazene, Andrew Stirrup, Sean Pymer, Joanne Palmer, Paris L. Cai, George E. Smith, Ian C. Chetter
Summary: This study investigated the diagnostic performance of the Edinburgh Claudication Questionnaire (ECQ) as a screening tool for suspected intermittent claudication patients. The results showed that the ECQ had a poor diagnostic performance and novel, low-resource diagnostic tools are needed for this population.
Review
Surgery
M. Dewi, B. L. Gwilym, A. H. Coxon, D. Carradice, D. C. Bosanquet
Summary: This systematic review aims to identify all recognized operative techniques for through-knee amputation (TKA) and develop a descriptive system for future research. A total of 906 papers were identified, with 28 included in the review. Key distinctions in operative technique include level of femur division, management of the patella, use of a muscular gastrocnaemius flap, and skin incisions. A 4-component classification system was developed to describe TKA techniques, using a shorthand nomenclature. Patient outcomes were not addressed. Importance rating: 8/10.
ANNALS OF VASCULAR SURGERY
(2023)
Editorial Material
Surgery
Daniel Carradice
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
(2023)
Review
Dermatology
Louise Hitchman, Joshua Totty, George E. Smith, Daniel Carradice, Maureen Twiddy, Cynthia Iglesias, David Russell, Ian C. Chetter
Summary: Emerging evidence suggests that ESWT may improve time to DFU healing, but the certainty of its effectiveness is low, limiting its translation into routine clinical practice.
INTERNATIONAL WOUND JOURNAL
(2023)
Article
Dermatology
Louise H. Hitchman, Joshua P. Totty, Paris Cai, George E. Smith, Daniel Carradice, Ian C. Chetter
Summary: This study assessed the feasibility of using extracorporeal shockwave therapy (ESWT) for diabetic foot ulcers (DFUs) and explored its potential clinical effects on wound healing and patient-reported benefits. The results showed that recruiting and retaining patients for single-arm ESWT studies is feasible, with no serious adverse events or side-effects. Some DFUs healed during follow-up and quality of life (QoL) scores improved.
JOURNAL OF WOUND CARE
(2023)
Review
Cardiac & Cardiovascular Systems
Vladica M. Velickovic, Daniel Carradice, Jonathan R. Boyle, Mohamad Hamady, Trevor Cleveland, Simon Neequaye, Aleksandra Ignjatovic, Dragana Bogdanovic, Jelena Savovic, Uwe Siebert
Summary: This umbrella review aimed to assess the quality of published meta-analyses, conduct a de-novo meta-analysis of available RCTs, and test the hypothesis of long-term mortality difference between OSR and EVAR. The results showed that EVAR had significantly favorable mortality up to four years, but there was no difference between EVAR and OSR in the longest available time period. The Cox model demonstrated a non-significant hazard ratio in favor of OSR, while the best-fitting generalized gamma model showed a slightly significant hazard ratio in favor of EVAR.
EXPERT REVIEW OF CARDIOVASCULAR THERAPY
(2023)
Article
Surgery
J. Heinz, J. Walshaw, J. Y. Kwan, J. Long, D. Carradice, J. Totty, K. M. Kontouli, P. Lainas, L. Hitchman, G. Smith, B. Huo, H. Guadalajara, D. Garcia-Olmo, D. Sharma, C. S. Biyani, J. Tomlinson, M. Loubani, R. Galli, R. Lathan, I. Chetter, M. Yiasemidou
Summary: This study aims to identify variations in SSI prevention practices within and between different surgical fields and countries, and provide references to help standardize SSI prevention practices.
FRONTIERS IN SURGERY
(2023)
Review
Surgery
Arthur J. M. Lim, Abduraheem H. Mohamed, Louise H. Hitchman, Ross Lathan, Bharadhwaj Ravindhran, Misha M. Sidapra, George Smith, Ian C. Chetter, Daniel Carradice
Summary: This systematic review and meta-analysis compared the outcomes of mechanochemical ablation (MOCA) and endovenous thermal ablation (EVTA). MOCA had a lower rate of anatomical occlusion after 1 year and 2-3 years, but there was no difference in procedural and postprocedural pain.
BRITISH JOURNAL OF SURGERY
(2023)
Review
Biochemistry & Molecular Biology
Bharadhwaj Ravindhran, Nicole Schafer, Annabel Howitt, Daniel Carradice, George Smith, Ian Chetter
Summary: This systematic review summarizes the current evidence on the molecular mechanisms of action of NPWT. The review finds that NPWT can stimulate the modulation of cytokines and growth factors, promoting an anti-inflammatory response.
EXPERT REVIEWS IN MOLECULAR MEDICINE
(2023)
Article
Surgery
Louise H. Hitchman, Abduraheem Mohamed, George E. Smith, Sean Pymer, Ian C. Chetter, James Forsyth, Daniel Carradice
Summary: The study assessed access to varicose vein treatments in the NHS and the impact of EBI. Many local varicose vein commissioning policies were found not compliant with NICE CG168, leading to a significant proportion of patients not receiving the recommended treatment.
BRITISH JOURNAL OF SURGERY
(2023)