Review
Neurosciences
Alexander N. Boytar, Marloes Dekker Nitert, Mark Morrision, Tina L. Skinner, David G. Jenkins
Summary: Physical activity is associated with reduced risks of colorectal cancer incidence, recurrence and mortality. The mechanism/s underlying this association remain unclear, but growing evidence suggests that different characteristics of the gut microbiota may play a role. Exercise can modify the gut microbiota, promoting its anti-tumorigenic characteristics, but further research is needed in the context of colorectal cancer.
JOURNAL OF PHYSIOLOGY-LONDON
(2022)
Review
Oncology
Ying Zhang, Jin-Soo Kim, Tian-Zhen Wang, Robert U. Newton, Daniel A. Galvao, Robert A. Gardiner, Michelle M. Hill, Dennis R. Taaffe
Summary: Exercise is increasingly being recognized as a valuable treatment strategy in managing prostate cancer by releasing extracellular vesicles that may influence disease outcomes, including suppressing tumor development.
FRONTIERS IN ONCOLOGY
(2021)
Review
Cell Biology
Duarte Barros, Elisa A. Marques, Jose Magalhaes, Joana Carvalho
Summary: Frailty is a complex condition that arises from dysregulation in multiple physiological systems, and age-related energy dysregulation may play a key role in frailty. Exercise is considered the most effective intervention to prevent and improve frailty, but the underlying mechanisms and molecules are not fully understood. Skeletal muscle functions as a secretory organ, producing exercise-related molecules such as myokines, which have important effects on cardiovascular, metabolic, immune, and neurological health.
AGEING RESEARCH REVIEWS
(2022)
Article
Plant Sciences
M. B. Hafeez, N. Zahra, N. Ahmad, Z. Shi, A. Raza, X. Wang, J. Li
Summary: Magnetic fields have specific roles in plant growth and development, and their application could potentially enhance crop productivity by changing physiological and biochemical processes. However, the effects of magnetic fields on plants are still not well understood, with contradictory outcomes from studies. Future research should focus on exploring the effects of magnetic fields on different crops.
Review
Biochemistry & Molecular Biology
Juan Zhang, Hong-Xi Xu, Jia-Qian Zhu, Yao-Xing Dou, Yan-Fang Xian, Zhi-Xiu Lin
Summary: Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor that regulates redox homeostasis and plays a pivotal role in processes such as cell proliferation and survival. It has been found to be aberrantly activated in many cancers and represents an important therapeutic target for cancer treatment.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES
(2023)
Article
Multidisciplinary Sciences
Faika Hassanein, Inas M. Masoud, Zeinab M. Awwad, Hussin Abdel-Salam, Mohamed Salem, Amany I. Shehata
Summary: The study revealed that the personal hygiene of swimmers can affect the spread of microbes in pools, resulting in a higher rate of intestinal parasitosis and a lower rate of Helicobacter pylori infection. Swimmers in the low score group are more susceptible to intestinal parasitic infections, which in turn affect their biochemical markers levels and performance.
SCIENTIFIC REPORTS
(2023)
Article
Multidisciplinary Sciences
Faika Hassanein, Inas M. Masoud, Zeinab M. Awwad, Hussin Abdel-Salam, Mohamed Salem, Amany I. Shehata
Summary: The study found that swimmers' personal hygiene affects microbial spread in pools, increasing the incidence of intestinal parasitosis. Additionally, swimming frequency and duration influenced infection status, potentially leading to anemia and abnormal physiological markers.
SCIENTIFIC REPORTS
(2023)
Review
Cardiac & Cardiovascular Systems
Audrey Harvey, Daniel Curnier, Philippe Dodin, Sylvia Abadir, Vincent Jacquemet, Maxime Caru
Summary: This review summarizes the difficulties long QT syndrome (LQTS) patients face in adopting a physically active lifestyle and discusses the current research perspectives in exercise and LQTS. The review highlights the subtype-specific repolarization responses of LQTS patients to sympathetic stress and the heterogeneity in measurement methods and quality, which makes inter-study comparisons difficult. The current recommendations may have long-term risks for LQTS patients, and future research should focus on determining the appropriate levels of exercise training for promoting ventricular repolarization normalization in LQTS.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2022)
Article
Environmental Sciences
Marwa F. F. Ali, Wafaa H. H. Mohamed
Summary: The present study investigated the genotoxic effects of pyridaben (PDB) in male Sprague Dawley rats. Four groups of rats were exposed to different doses of PDB for 4 weeks. Blood samples, femoral bone marrow, and liver samples were collected for various analyses. The results showed changes in hematological and biochemical parameters, increased gene expression of IL-6 and Casp-3, and histopathological findings in the liver with PDB exposure. However, there was no significant change in chromosomal aberrations.
ENVIRONMENTAL TOXICOLOGY
(2023)
Review
Nutrition & Dietetics
Sarah J. Wherry, Ryan M. Miller, Sarah H. Jeong, Kristen M. Beavers
Summary: Caloric restriction-induced weight loss can lead to bone density loss in older adults, and while exercise has positive effects on maintaining bone density, its effectiveness in mitigating CR-induced bone loss remains uncertain.
Article
Environmental Sciences
Aslihan Sur Arslan, Ismail Seven, Seda Iflazoglu Mutlu, Gozde Arkali, Nurgul Birben, Pinar Tatli Seven
Summary: This study evaluated the ameliorative role of quercetin in laying quails exposed to lead poisoning. The results showed that quercetin supplementation can alleviate the oxidative stress, biochemical changes, and apoptosis caused by lead exposure in quails.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2022)
Article
Biochemistry & Molecular Biology
Maja D. Nesic, Tanja Ducic, Mara Goncalves, Milutin Stepic, Manuel Algarra, Juan Soto, Branislava Gemovic, Teresa J. Bandosz, Marijana Petkovic
Summary: This study investigated the effects of carbon dots and N-carbon dots loaded with Ru-complex on ovarian cancer and osteosarcoma cells induced by UV illumination. The results demonstrated the selective action of the loaded nanomaterials in photodynamic therapy and evaluated their surface and optical properties.
CHEMICO-BIOLOGICAL INTERACTIONS
(2022)
Review
Instruments & Instrumentation
Kenny Tjo, Pegah Varamini
Summary: Breast cancer remains a common and deadly cancer type among women globally. Nanodiamonds show promising potential in breast cancer therapy by overcoming limitations of conventional treatment methods, such as chemoresistance and lack of selectivity in aggressive cancer subtypes.
DRUG DELIVERY AND TRANSLATIONAL RESEARCH
(2022)
Article
Oncology
K. Drareni, M. Bensafi, A. Giboreau, A. Dougkas
Summary: Chemotherapy-induced taste and smell alterations have a negative impact on food perception, with severe alterations leading to more frequent food perception issues. The stage of chemotherapy treatment may affect the severity of taste and smell alterations.
SUPPORTIVE CARE IN CANCER
(2021)
Article
Environmental Sciences
Fatma M. El-Demerdash, Raghda A. El-Sayed, Mohamed M. Abdel-Daim
Summary: The study found that exposure to hexavalent chromium led to significant changes in hematological parameters, oxidative stress markers, and glutathione content in rats. Enzymatic antioxidants, liver enzymes, alkaline phosphatase activities, and protein levels were all adversely affected. However, administration of rosemary essential oil helped restore these parameters and improved antioxidant status, demonstrating its effectiveness in modulating hexavalent chromium-induced hepatotoxicity.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Hospitality, Leisure, Sport & Tourism
Darren L. Richardson, Michael J. Duncan, Alfonso Jimenez, Paul M. Juris, Neil D. Clarke
JOURNAL OF SPORT AND HEALTH SCIENCE
(2020)
Article
Urology & Nephrology
Scott McGuire, Elizabeth J. Horton, Derek Renshaw, Klaris Chan, Alfonso Jimenez, Helen Maddock, Nithya Krishnan, Gordon McGregor
Summary: Intra-dialytic exercise can significantly reduce ischemic wall motion abnormalities, providing acute cardiac protection. Global cardiac function and LV volumetric parameters were not significantly affected by exercise.
CLINICAL KIDNEY JOURNAL
(2021)
Article
Green & Sustainable Science & Technology
Xian Mayo, Antonio Luque-Casado, Alfonso Jimenez, Fernando del Villar
Review
Sport Sciences
Ana Myriam Lavin-Perez, Daniel Collado-Mateo, Xian Mayo, Liam Humphreys, Gary Liguori, Robert James Copeland, Fernando Del Villar Alvarez, Alfonso Jimenez
Summary: High-intensity training has significant effects on improving cardiorespiratory fitness in cancer patients, especially for those who start exercising before treatment and have interventions lasting longer than eight weeks.
SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
(2021)
Article
Green & Sustainable Science & Technology
Antonio Luque-Casado, Xian Mayo, Ana Myriam Lavin-Perez, Alfonso Jimenez, Fernando Del Villar
Summary: The research revealed significant gender differences in physical activity levels and autonomous forms of motivation among adolescent girls and young women, with females being at a disadvantage and the differences becoming more pronounced with age. Qualitative findings indicated that key cognitive and contextual mechanisms influence the volitional undertaking of physical activity among women. Therefore, implementing gender-sensitive policy approaches is crucial in fostering voluntary engagement in physical activity among adolescent girls and young women.
Article
Public, Environmental & Occupational Health
J. Lopez-Fernandez, A. Lopez-Valenciano, X. Mayo, G. Liguori, M. A. Lamb, R. J. Copeland, A. Jimenez
Summary: The study found that the prevalence of sedentary behavior among EU adolescents remained at a high level from 2002 to 2017, with no significant differences between sexes. No improvements in sedentary behavior were observed.
Review
Multidisciplinary Sciences
Ana Myriam Lavin-Perez, Daniel Collado-Mateo, Xian Mayo, Gary Liguori, Liam Humphreys, Robert James Copeland, Alfonso Jimenez
Summary: High-intensity training (HIT) has a positive impact on improving the health-related quality of life (HRQoL) of cancer patients and survivors, especially during cancer treatment and under certain conditions of training duration, frequency, and volume.
SCIENTIFIC REPORTS
(2021)
Article
Medicine, General & Internal
Jorge Lopez Fernandez, Alejandro Lopez-Valenciano, Xian Mayo, Elizabeth Horton, Ivan Clavel, Gary Liguori, Alfonso Jimenez
Summary: The study found that leisure centre members have lower levels of physical inactivity (PIA) and higher levels of high-intensity physical activity compared to the general population; women have higher levels of PIA and lower levels of high-PA compared to men; as age increases, the prevalence of PIA increases while the prevalence of high-PA decreases.
Review
Psychology, Multidisciplinary
Ana Myriam Lavin-Perez, Daniel Collado-Mateo, Xian Mayo, Gary Liguori, Liam Humphreys, Alfonso Jimenez
Summary: This study analyzed the effects of exercise programs on the autonomic modulation, measured by HRV, of patients with cancer and its survivors. The results showed that exercise can improve both time-domain and frequency-domain HRV measures, indicating positive effects on autonomic modulation in patients.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Public, Environmental & Occupational Health
X. Mayo, E. Iglesias-Soler, G. Liguori, R. J. Copeland, I Clavel, F. del Villar, A. Jimenez
Summary: This study analyzed the Eurobarometer data to examine the modifiable factors affecting physical inactivity. The findings suggest that the existing model has a limited ability to detect physical inactivity, accurately identifying only a small percentage of inactive individuals.
EUROPEAN JOURNAL OF PUBLIC HEALTH
(2022)
Review
Geriatrics & Gerontology
Joel Puente-Fernandez, Eneko Larumbe-Zabala, Alfonso Jimenez, Gary Liguori, Claire J. L. Rossato, Xian Mayo, Fernando Naclerio
Summary: This review examined the efficacy of protein-based multi-ingredient (MTN) supplements in optimizing body composition and physical performance in middle-aged and older adults. The findings suggest that MTN supplementation does not provide significant additional benefits compared to isocaloric and single-nutrient supplements. Therefore, for healthy and physically active middle-aged and older adults, there is no added advantage to consuming MTN supplements over COMP.
EXPERIMENTAL GERONTOLOGY
(2023)
Article
Physiology
Ana Myriam Lavin-Perez, Daniel Collado-Mateo, Carmen Hinojo Gonzalez, Marco Batista, Xian Mayo, Cristina Ruisanchez Villar, Alfonso Jimenez
Summary: Exercise interventions have the potential to improve clinical, physical, and psychosocial outcomes for breast cancer survivors. This study found that exercise has an impact on autonomic modulation and can be measured through daily heart rate variability. These findings support the importance of exercise as a rehabilitation strategy for breast cancer survivors post-chemotherapy and radiotherapy.
FRONTIERS IN PHYSIOLOGY
(2023)
Article
Oncology
Ana Myriam Lavin-Perez, Daniel Collado-Mateo, Carmen Hinojo Gonzalez, Ana de Juan Ferre, Cristina Ruisanchez Villar, Xian Mayo, Alfonso Jimenez
Summary: The purpose of this study was to analyze the changes in heart rate variability (HRV) 24h, 48h, and 72h after exercise in breast cancer survivors. The results showed a significant decrease in HRV 24h after exercise, but a gradual recovery was observed after 48h. Therefore, HRV can be used as a useful tool to monitor the recovery and exercise tolerance of breast cancer survivors.
FRONTIERS IN ONCOLOGY
(2023)
Review
Public, Environmental & Occupational Health
Nadja Willinger, James Steele, Lou Atkinson, Gary Liguori, Alfonso Jimenez, Steve Mann, Elizabeth Horton
Summary: This study summarizes the effectiveness of structured physical activity interventions on physical activity outcomes and finds a lack of evidence for improving physical activity levels. While retention rates are commonly reported and are similar between interventions and controls, adoption, maintenance, and adherence rates were rarely reported, making it difficult to interpret the effectiveness of structured physical activity interventions.
JOURNAL OF PHYSICAL ACTIVITY & HEALTH
(2021)
Article
Public, Environmental & Occupational Health
Nikita Rowley, James Steele, Steve Mann, Alfonso Jimenez, Elizabeth Horton
Summary: The research sheds light on the varying delivery approaches of exercise referral schemes in England, with most schemes typically lasting 12 weeks and offering participants 2 exercise sessions in a fitness gym or studio per week. Adherence is usually measured through attendance, with nonexercise components and program management differing by scheme.
JOURNAL OF PHYSICAL ACTIVITY & HEALTH
(2021)