N-terminally and C-terminally truncated forms of glucose-dependent insulinotropic polypeptide are high-affinity competitive antagonists of the human GIP receptor

Sequential induction of beta cell rest and stimulation using stable GIP inhibitor and GLP-1 mimetic peptides improves metabolic control in C57BL/KsJ db/db mice

(2015) Varun Pathak et al.   DIABETOLOGIA

Antagonism of gastric inhibitory polypeptide (GIP) by palmitoylation of GIP analogues with N- and C-terminal modifications improves obesity and metabolic control in high fat fed mice

(2015) V. Pathak et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Interaction of Chemokines with their Receptors – From Initial Chemokine Binding to Receptor Activating Steps

(2014) Stefanie Thiele et al.   CURRENT MEDICINAL CHEMISTRY

Selectivity of peptide ligands for the human incretin receptors expressed in HEK-293 cells

(2014) S. Al-Sabah et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Glucose-Dependent Insulinotropic Polypeptide Inhibits Bone Resorption in Humans

(2014) Anne Nissen et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Glucose-dependent insulinotropic polypeptide (GIP) receptor deletion leads to reduced bone strength and quality

(2013) Aleksandra Mieczkowska et al.   BONE

The Concise Guide to PHARMACOLOGY 2013/14: G Protein-Coupled Receptors

(2013) Stephen P.H. Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

Pharmacology, Physiology, and Mechanisms of Incretin Hormone Action

(2013) Jonathan E. Campbell et al.   Cell Metabolism

Glucose-dependent insulinotropic polypeptide has impaired effect on abdominal, subcutaneous adipose tissue metabolism in obese subjects

(2013) M Asmar et al.   INTERNATIONAL JOURNAL OF OBESITY

Structural and Pharmacological Characterization of Novel Potent and Selective Monoclonal Antibody Antagonists of Glucose-dependent Insulinotropic Polypeptide Receptor

(2013) Peter Ravn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands

(2013) Adam J. Pawson et al.   NUCLEIC ACIDS RESEARCH

Glucose-dependent insulinotropic polypeptide receptor deficiency leads to modifications of trabecular bone volume and quality in mice

(2012) Christine Gaudin-Audrain et al.   BONE

Glucagon-like peptide-1 (GLP-1) receptor agonism or DPP-4 inhibition does not accelerate neoplasia in carcinogen treated mice

(2012) Hannelouise Kissow et al.   REGULATORY PEPTIDES

Glucose-Dependent Insulinotropic Polypeptide: A Bifunctional Glucose-Dependent Regulator of Glucagon and Insulin Secretion in Humans

(2011) M. Christensen et al.   DIABETES

Loss of Incretin Effect Is a Specific, Important, and Early Characteristic of Type 2 Diabetes

(2011) J. J. Holst et al.   DIABETES CARE

Biological and functional characteristics of a novel low-molecular weight antagonist of glucose-dependent insulinotropic polypeptide receptor, SKL-14959, in vitro and in vivo

(2011) T. Nakamura et al.   DIABETES OBESITY & METABOLISM

Differential processing of pro-glucose-dependent insulinotropic polypeptide in gut

(2010) Yukihiro Fujita et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Characterization and biological actions of N-terminal truncated forms of glucose-dependent insulinotropic polypeptide

(2010) Barry D. Kerr et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Molecular basis of parathyroid hormone receptor signaling and trafficking: a family B GPCR paradigm

(2010) Jean-Pierre Vilardaga et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Glucose-Dependent Insulinotropic Polypeptide Is Expressed in Pancreatic Islet α-Cells and Promotes Insulin Secretion

(2010) Yukihiro Fujita et al.   GASTROENTEROLOGY

Identification of Determinants of Glucose-Dependent Insulinotropic Polypeptide Receptor That Interact with N-Terminal Biologically Active Region of the Natural Ligand

(2010) T. Yaqub et al.   MOLECULAR PHARMACOLOGY

Mechanisms underlying the rapid degradation and elimination of the incretin hormones GLP-1 and GIP

(2009) Rolf Mentlein   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Incretin-Based Therapy of Type 2 Diabetes Mellitus

(2009) Filip Knop et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

PositiveVersusNegative Modulation of Different Endogenous Chemokines for CC-chemokine Receptor 1 by Small Molecule Agonists through AllostericVersusOrthosteric Binding

(2008) Pia C. Jensen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY