Journal
JOURNAL OF CHROMATOGRAPHY A
Volume 1619, Issue -, Pages -Publisher
ELSEVIER
DOI: 10.1016/j.chroma.2020.460913
Keywords
Teamed boronate affinity; Ring-opening polymerization; Magnetic solid-phase extraction; Polyphenols; Flos Lonicerae Beverage
Funding
- National Natural Science Foundation of China [21605114]
- Tianjin Natural Science Foundation [17JCQNJC13300]
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Traditional boron affinity materials usually capture cis-diol-containing molecules under alkaline condition, but some cis-diol-containing molecules, such as polyphenols, are unstable and easy to be oxidized and degraded under alkaline condition. Teamed boronate affinity (TBA) can specifically capture cis-diol-containing molecules under neutral condition. However, the report about combination of TBA and magnetic nanoparticle for the extraction was rare. Here, we fabricated two kinds of teamed boronate affinity magnetic nanoparticles (TBAMP), including Fe3O4@TBAP and Fe3O4@SiO2@TBAP. Adsorption capacities of cis-diol-containing molecules on the latter were similar to these on the former, but the latter possessed more superior regeneration performance than the former. Therefore, the TBAMP with more superior regeneration performance was used as magnetic solid-phase extraction (MSPE) adsorbent for capturing polyphenols under neutral condition. The TBAMP MSPE was optimized in detail, and combined with high-performance liquid chromatography-mass spectrometry (HPLC-MS) for the simultaneous determination of 13 kinds of polyphenols from Flos Lonicerae Beverage. The proposed method showed low limit of detection between 0.01 and 0.20 ng mL(-1). In blank Flos Lonicerae Beverage, 11 kinds of polyphenols ranged from 0.54 ng mL(-1) to 52.99 ng mL(-1) were detected. In the standard addition method, recoveries of cis-diol-containing polyphenols were between 85.7% and 102.1% with intra-day and inter-day relative standard deviation ranging from 3.2% to 5.1% and 5.3% to 7.3%, respectively. (C) 2020 Elsevier B.V. All rights reserved.
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