TORC1 regulates vacuole membrane composition through ubiquitin- and ESCRT-dependent microautophagy

Mdm1 maintains endoplasmic reticulum homeostasis by spatially regulating lipid droplet biogenesis

(2019) Hanaa Hariri et al.   JOURNAL OF CELL BIOLOGY

A spatially and functionally distinct pool of TORC1 defines signaling endosomes in yeast

(2019) Riko Hatakeyama et al.   Autophagy

The complex relationship between TFEB transcription factor phosphorylation and subcellular localization

(2018) Rosa Puertollano et al.   EMBO JOURNAL

Sorting of a multi-subunit ubiquitin ligase complex in the endolysosome system

(2018) Xi Yang et al.   eLife

Vacuolar hydrolysis and efflux: current knowledge and unanswered questions

(2018) Katherine R. Parzych et al.   Autophagy

Spatially Distinct Pools of TORC1 Balance Protein Homeostasis

(2018) Riko Hatakeyama et al.   MOLECULAR CELL

Evidence for ESCRT- and clathrin-dependent microautophagy

(2017) Masahide Oku et al.   JOURNAL OF CELL BIOLOGY

TFEB regulates lysosomal positioning by modulating TMEM55B expression and JIP4 recruitment to lysosomes

(2017) Rose Willett et al.   Nature Communications

ESCRTs function directly on the lysosome membrane to downregulate ubiquitinated lysosomal membrane proteins

(2017) Lu Zhu et al.   eLife

Recruitment dynamics of ESCRT-III and Vps4 to endosomes and implications for reverse membrane budding

(2017) Manuel Alonso Y Adell et al.   eLife

The Lysosome as a Regulatory Hub

(2016) Rushika M. Perera et al.   Annual Review of Cell and Developmental Biology

The lysosome as a command-and-control center for cellular metabolism

(2016) Chun-Yan Lim et al.   JOURNAL OF CELL BIOLOGY

Membrane-anchored ubiquitin ligase complex is required for the turnover of lysosomal membrane proteins

(2015) Ming Li et al.   JOURNAL OF CELL BIOLOGY

Ubiquitin-Dependent Lysosomal Membrane Protein Sorting and Degradation

(2015) Ming Li et al.   MOLECULAR CELL

The coordinated action of the MVB pathway and autophagy ensures cell survival during starvation

(2015) Martin Müller et al.   eLife

Loss of ATP-dependent lysine uptake in the vacuolar membrane vesicles ofSaccharomyces cerevisiae ypq1∆ mutant

(2014) Takayuki Sekito et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Identification of Candidate Substrates for the Golgi Tul1 E3 Ligase Using Quantitative diGly Proteomics in Yeast

(2014) Zongtian Tong et al.   MOLECULAR & CELLULAR PROTEOMICS

Roles for PI(3,5)P2 in nutrient sensing through TORC1

(2014) Natsuko Jin et al.   MOLECULAR BIOLOGY OF THE CELL

Structural basis of starvation-induced assembly of the autophagy initiation complex

(2014) Yuko Fujioka et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Nutrient-Responsive Transcription Factor TFE3 Promotes Autophagy, Lysosomal Biogenesis, and Clearance of Cellular Debris

(2014) J. A. Martina et al.   Science Signaling

Characterization of an M28 metalloprotease family member residing in the yeast vacuole

(2013) Karen A. Hecht et al.   FEMS YEAST RESEARCH

Signals from the lysosome: a control centre for cellular clearance and energy metabolism

(2013) Carmine Settembre et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Ume6-Sin3-Rpd3 complex regulatesATG8transcription to control autophagosome size

(2012) Steven K. Backues et al.   Autophagy

Binding of the Atg1/ULK1 kinase to the ubiquitin-like protein Atg8 regulates autophagy

(2012) Claudine Kraft et al.   EMBO JOURNAL

A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB

(2012) Carmine Settembre et al.   EMBO JOURNAL

Ume6 transcription factor is part of a signaling cascade that regulates autophagy

(2012) C. R. Bartholomew et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TFEB Links Autophagy to Lysosomal Biogenesis

(2011) C. Settembre et al.   SCIENCE

Sna3 Is an Rsp5 Adaptor Protein that Relies on Ubiquitination for Its MVB Sorting

(2011) Chris MacDonald et al.   TRAFFIC

The Rapamycin-sensitive Phosphoproteome Reveals That TOR Controls Protein Kinase A Toward Some But Not All Substrates

(2010) Alexandre Soulard et al.   MOLECULAR BIOLOGY OF THE CELL

mTOR signaling at a glance

(2009) M. Laplante et al.   JOURNAL OF CELL SCIENCE

A Gene Network Regulating Lysosomal Biogenesis and Function

(2009) Marco Sardiello et al.   SCIENCE

The yeast lysosome-like vacuole: Endpoint and crossroads

(2008) Sheena Claire Li et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Caffeine extends yeast lifespan by targeting TORC1

(2008) Valeria Wanke et al.   MOLECULAR MICROBIOLOGY