Rac1 Inhibition Via Srgap2 Restrains Inflammatory Osteoclastogenesis and Limits the Clastokine, SLIT3

A Novel Divergent Gene Transcription Paradigm—the Decisive, Brain-Specific, Neural |-Srgap2–Fam72a-| Master Gene Paradigm

(2019) Nguyen Thi Thanh Ho et al.   MOLECULAR NEUROBIOLOGY

Leukocyte Cytoskeleton Polarization Is Initiated by Plasma Membrane Curvature from Cell Attachment

(2019) Chunguang Ren et al.   DEVELOPMENTAL CELL

Osteoclast-secreted SLIT3 coordinates bone resorption and formation

(2018) Beom-Jun Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Targeting skeletal endothelium to ameliorate bone loss

(2018) Ren Xu et al.   NATURE MEDICINE

Mind the (sr)GAP – roles of Slit–Robo GAPs in neurons, brains and beyond

(2017) Bethany Lucas et al.   JOURNAL OF CELL SCIENCE

Deletion of the membrane complement inhibitor CD59a drives age and gender-dependent alterations to bone phenotype in mice

(2016) Anja C. Bloom et al.   BONE

SRGAP2 and Its Human-Specific Paralog Co-Regulate the Development of Excitatory and Inhibitory Synapses

(2016) Matteo Fossati et al.   NEURON

Deletion of BMP receptor type IB decreased bone mass in association with compromised osteoblastic differentiation of bone marrow mesenchymal progenitors

(2016) Ce Shi et al.   Scientific Reports

Contradictory role of CD97 in basal and tumor necrosis factor α-induced osteoclastogenesis in vivo

(2015) Hee Yeon Won et al.   Arthritis & Rheumatology

Molecular Mechanisms of Bone Metastasis and Associated Muscle Weakness

(2014) D. L. Waning et al.   CLINICAL CANCER RESEARCH

Biology of the RANKL–RANK–OPG System in Immunity, Bone, and Beyond

(2014) Matthew C. Walsh et al.   Frontiers in Immunology

Immunological Reaction in TNF-α-Mediated Osteoclast Formation and Bone ResorptionIn VitroandIn Vivo

(2013) Hideki Kitaura et al.   Clinical & Developmental Immunology

miR-29 Promotes Murine Osteoclastogenesis by Regulating Osteoclast Commitment and Migration

(2013) Tiziana Franceschetti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Three-dimensional microarchitecture of adolescent cancellous bone

(2012) Ming Ding et al.   BONE

Inhibition of SRGAP2 Function by Its Human-Specific Paralogs Induces Neoteny during Spine Maturation

(2012) Cécile Charrier et al.   CELL

Evolution of Human-Specific Neural SRGAP2 Genes by Incomplete Segmental Duplication

(2012) Megan Y. Dennis et al.   CELL

Standardized nomenclature, symbols, and units for bone histomorphometry: A 2012 update of the report of the ASBMR Histomorphometry Nomenclature Committee

(2012) David W Dempster et al.   JOURNAL OF BONE AND MINERAL RESEARCH

TNF-stimulated MAP kinase activation mediated by a Rho family GTPase signaling pathway

(2011) S. Kant et al.   GENES & DEVELOPMENT

Effects of miR-335-5p in modulating osteogenic differentiation by specifically downregulating Wnt antagonist DKK1

(2011) Jin Zhang et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Rac deletion in osteoclasts causes severe osteopetrosis

(2011) M. Croke et al.   JOURNAL OF CELL SCIENCE

Bi-modal Regulation of a Formin by srGAP2

(2010) Frank M. Mason et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Rac1 exchange factor Dock5 is essential for bone resorption by osteoclasts

(2010) Virginie Vives et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Cdc42 regulates bone modeling and remodeling in mice by modulating RANKL/M-CSF signaling and osteoclast polarization

(2010) Yuji Ito et al.   JOURNAL OF CLINICAL INVESTIGATION

Skeletal sexual dimorphism: relative contribution of sex steroids, GH–IGF1, and mechanical loading

(2010) Filip Callewaert et al.   JOURNAL OF ENDOCRINOLOGY

The F-BAR Domain of srGAP2 Induces Membrane Protrusions Required for Neuronal Migration and Morphogenesis

(2009) Sabrice Guerrier et al.   CELL

Selective inhibition of RANK blocks osteoclast maturation and function and prevents bone loss in mice

(2009) Hyunsoo Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Osteoimmunology: Interactions of the Bone and Immune System

(2008) Joseph Lorenzo et al.   ENDOCRINE REVIEWS

Regulation of bone formation by osteoclasts involves Wnt/BMP signaling and the chemokine sphingosine-1-phosphate

(2008) L. Pederson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TNF inhibits production of stromal cell-derived factor 1 by bone stromal cells and increases osteoclast precursor mobilization from bone marrow to peripheral blood

(2008) Qian Zhang et al.   ARTHRITIS RESEARCH & THERAPY