Journal
JOURNAL OF BIOLOGICAL PHYSICS
Volume 45, Issue 4, Pages 379-394Publisher
SPRINGER
DOI: 10.1007/s10867-019-09534-4
Keywords
Blood fluid dynamics; Red blood cell; Microcirculation; Hematocrit; Suspension; Cell-free layer
Categories
Ask authors/readers for more resources
The Fahr AE us-Lindqvist effect is usually explained from a physical point of view with the so-called Haynes' marginal zone theory, i.e., migration of red blood cells (RBCs) to a core layer surrounded by an annular RBCs-free plasma layer. In this paper we show that the marginal layer, though causing a substantial reduction in flow resistance and increasing discharge, does not reduce the rate of energy dissipation. This fact is not surprising if one considers the electric analog of the flow in a vessel: a resistance reduction increases both the current intensity (i.e., the discharge) and the energy dissipation. This result is obtained by considering six rheological models that relate the blood viscosity to hematocrit (volume fraction occupied by erythrocytes). Some physiological implications are discussed.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available