Mepolizumab add-on therapy in a real world cohort of patients with severe eosinophilic asthma: response rate, effectiveness, and safety

Understanding Asthma Phenotypes, Endotypes, and Mechanisms of Disease

(2018) Merin E. Kuruvilla et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Analysis of the drop-out rate in patients receiving mepolizumab for severe asthma in real life

(2018) Carlo Lombardi et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

“I have lost in every facet of my life”: the hidden burden of severe asthma

(2017) Juliet M. Foster et al.   EUROPEAN RESPIRATORY JOURNAL

Severe asthma and quality of life

(2017) Elham Hossny et al.   World Allergy Organization Journal

Effects of conventional tobacco smoke and nicotine-free cigarette smoke on airway inflammation, airway remodelling and lung function in a triple allergen model of severe asthma

(2016) C. Tilp et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Long-term Efficacy and Safety of Mepolizumab in Patients With Severe Eosinophilic Asthma: A Multi-center, Open-label, Phase IIIb Study

(2016) Njira Lugogo et al.   CLINICAL THERAPEUTICS

Drop-out rate among patients treated with omalizumab for severe asthma: Literature review and real-life experience

(2016) M. Caminati et al.   BMC Pulmonary Medicine

Severe eosinophilic asthma treated with mepolizumab stratified by baseline eosinophil thresholds: a secondary analysis of the DREAM and MENSA studies

(2016) Hector G Ortega et al.   Lancet Respiratory Medicine

The prevalence of severe refractory asthma

(2015) Pieter-Paul W. Hekking et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Distinct endotypes of steroid-resistant asthma characterized by IL-17Ahigh and IFN-γhigh immunophenotypes: Potential benefits of calcitriol

(2015) Emma S. Chambers et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Oral Glucocorticoid-Sparing Effect of Mepolizumab in Eosinophilic Asthma

(2014) Elisabeth H. Bel et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mepolizumab Treatment in Patients with Severe Eosinophilic Asthma

(2014) Hector G. Ortega et al.   NEW ENGLAND JOURNAL OF MEDICINE

Heterogeneity of phenotypes in severe asthmatics. The Belgian Severe Asthma Registry (BSAR)

(2014) F. Schleich et al.   RESPIRATORY MEDICINE

The cost of treating severe refractory asthma in the UK: an economic analysis from the British Thoracic Society Difficult Asthma Registry

(2014) S. O'Neill et al.   THORAX

International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma

(2013) K. F. Chung et al.   EUROPEAN RESPIRATORY JOURNAL

Effects of benralizumab on airway eosinophils in asthmatic patients with sputum eosinophilia

(2013) Michel Laviolette et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial

(2012) Ian D Pavord et al.   LANCET