Unraveling epigenomic abnormality in azoospermic human males by WGBS, RNA-Seq, and transcriptome profiling analyses

Sequencing of a ‘mouse azoospermia’ gene panel in azoospermic men: identification of RNF212 and STAG3 mutations as novel genetic causes of meiotic arrest

(2019) A Riera-Escamilla et al.   HUMAN REPRODUCTION

SOHLHs Might Be Gametogenesis-Specific bHLH Transcriptional Regulation Factors in Crassostrea gigas

(2019) Guang Qian et al.   Frontiers in Physiology

DNA methylation patterns vary in boar sperm cells with different levels of DNA fragmentation

(2019) Abdolrahman Khezri et al.   BMC GENOMICS

Single-Cell RNA Sequencing Analysis Reveals Sequential Cell Fate Transition during Human Spermatogenesis

(2018) Mei Wang et al.   Cell Stem Cell

A Comprehensive Roadmap of Murine Spermatogenesis Defined by Single-Cell RNA-Seq

(2018) Christopher Daniel Green et al.   DEVELOPMENTAL CELL

CRISPR–Cas9-mediated base-editing screening in mice identifies DND1 amino acids that are critical for primordial germ cell development

(2018) Qing Li et al.   NATURE CELL BIOLOGY

The adult human testis transcriptional cell atlas

(2018) Jingtao Guo et al.   CELL RESEARCH

Genome-wide differential methylation analyses identifies methylation signatures of male infertility

(2018) Kumar Mohanty Sujit et al.   HUMAN REPRODUCTION

The Mammalian Spermatogenesis Single-Cell Transcriptome, from Spermatogonial Stem Cells to Spermatids

(2018) Brian P. Hermann et al.   Cell Reports

DAZL is a master translational regulator of murine spermatogenesis

(2018) Haixin Li et al.   National Science Review

Transcriptome-wide association study revealed two novel genes associated with nonobstructive azoospermia in a Chinese population

(2017) Tingting Jiang et al.   FERTILITY AND STERILITY

Human-specific subcellular compartmentalization of P-element induced wimpy testis-like (PIWIL) granules during germ cell development and spermatogenesis

(2017) Maria Gomes Fernandes et al.   HUMAN REPRODUCTION

MAEL promoter hypermethylation is associated with de-repression of LINE-1 in human hypospermatogenesis

(2017) Yu-Sheng Cheng et al.   HUMAN REPRODUCTION

Mutation in TDRD9 causes non-obstructive azoospermia in infertile men

(2017) Maram Arafat et al.   JOURNAL OF MEDICAL GENETICS

DND1 maintains germline stem cells via recruitment of the CCR4–NOT complex to target mRNAs

(2017) Masashi Yamaji et al.   NATURE

PNLDC1 is essential for piRNA 3′ end trimming and transposon silencing during spermatogenesis in mice

(2017) Deqiang Ding et al.   Nature Communications

Integrated Analysis of DNA Methylation and mRNA Expression Profiles to Identify Key Genes in Severe Oligozoospermia

(2017) Zhiming Li et al.   Frontiers in Physiology

Obesity and Bariatric Surgery Drive Epigenetic Variation of Spermatozoa in Humans

(2016) Ida Donkin et al.   Cell Metabolism

Highly conserved epigenetic regulation of BOULE and DAZL is associated with human fertility

(2016) Chenwang Zhang et al.   FASEB JOURNAL

Epigenetic profiles signify cell fate plasticity in unipotent spermatogonial stem and progenitor cells

(2016) Ying Liu et al.   Nature Communications

Dazl is a target RNA suppressed by mammalian NANOS2 in sexually differentiating male germ cells

(2016) Yuzuru Kato et al.   Nature Communications

Dynamics of the Transcriptome during Human Spermatogenesis: Predicting the Potential Key Genes Regulating Male Gametes Generation

(2016) Zijue Zhu et al.   Scientific Reports

TOPAZ1, a germ cell specific factor, is essential for male meiotic progression

(2015) Alix Luangpraseuth-Prosper et al.   DEVELOPMENTAL BIOLOGY

Dead end1 is an essential partner of NANOS2 for selective binding of target RNAs in male germ cell development

(2015) A. Suzuki et al.   EMBO REPORTS

Gene Body Methylation Can Alter Gene Expression and Is a Therapeutic Target in Cancer

(2014) Xiaojing Yang et al.   CANCER CELL

Integrative DNA methylation and gene expression analysis identifies discoidin domain receptor 1 association with idiopathic nonobstructive azoospermia

(2014) Ranjith Ramasamy et al.   FERTILITY AND STERILITY

Environmental epigenetic inheritance through gametes and implications for human reproduction

(2014) Yanchang Wei et al.   HUMAN REPRODUCTION UPDATE

Testicular differentiation factor SF-1 is required for human spleen development

(2014) David Zangen et al.   JOURNAL OF CLINICAL INVESTIGATION

MethHC: a database of DNA methylation and gene expression in human cancer

(2014) Wei-Yun Huang et al.   NUCLEIC ACIDS RESEARCH

Epigenetic Regulation of Sox30 Is Associated with Testis Development in Mice

(2014) Fei Han et al.   PLoS One

A novel application of cell-free seminal mRNA: non-invasive identification of the presence of germ cells or complete obstruction in men with azoospermia

(2012) Honggang Li et al.   HUMAN REPRODUCTION

Functions of DNA methylation: islands, start sites, gene bodies and beyond

(2012) Peter A. Jones   NATURE REVIEWS GENETICS

A “mille-feuille” of silencing: Epigenetic control of transposable elements

(2011) Mélanie Rigal et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Incorrect DNA methylation of the DAZL promoter CpG island associates with defective human sperm†

(2010) Paulo Navarro-Costa et al.   HUMAN REPRODUCTION

Genetic variants in Piwi-interacting RNA pathway genes confer susceptibility to spermatogenic failure in a Chinese population

(2010) A. Gu et al.   HUMAN REPRODUCTION

MTHFR promoter hypermethylation in testicular biopsies of patients with non-obstructive azoospermia: the role of epigenetics in male infertility

(2009) N. Khazamipour et al.   HUMAN REPRODUCTION

Human DAZL, DAZ and BOULE genes modulate primordial germ-cell and haploid gamete formation

(2009) Kehkooi Kee et al.   NATURE

Mutations inNR5A1Associated with Ovarian Insufficiency

(2009) Diana Lourenço et al.   NEW ENGLAND JOURNAL OF MEDICINE

Large-scale discovery of insertion hotspots and preferential integration sites of human transposed elements

(2009) Asaf Levy et al.   NUCLEIC ACIDS RESEARCH

Active Alu retrotransposons in the human genome

(2008) E. A. Bennett et al.   GENOME RESEARCH