New insights into the vancomycin‐induced nephrotoxicity using in vitro metabolomics combined with physiologically based pharmacokinetic modeling

The dosing and monitoring of vancomycin – what is the best way forward?

(2018) Philip G. Drennan et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Vancomycin induces reactive oxygen species-dependent apoptosis via mitochondrial cardiolipin peroxidation in renal tubular epithelial cells

(2017) Yuya Sakamoto et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Incidence and risk factors of acute kidney injury associated with continuous intravenous high-dose vancomycin in critically ill patients

(2017) Guillaume Lacave et al.   MEDICINE

MBD2 upregulates miR-301a-5p to induce kidney cell apoptosis during vancomycin-induced AKI

(2017) Juan Wang et al.   Cell Death & Disease

Vancomycin Trough and Acute Kidney Injury: A Large Retrospective, Cohort Study

(2016) Kassem Hammoud et al.   AMERICAN JOURNAL OF NEPHROLOGY

Evaluation of Vancomycin Exposures Associated with Elevations in Novel Urinary Biomarkers of Acute Kidney Injury in Vancomycin-Treated Rats

(2016) Nathaniel J. Rhodes et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Development of a Physiologically Based Pharmacokinetic Modelling Approach to Predict the Pharmacokinetics of Vancomycin in Critically Ill Septic Patients

(2016) Christian Radke et al.   CLINICAL PHARMACOKINETICS

Therapeutic drug monitoring of vancomycin: a guideline of the Division of Therapeutic Drug Monitoring, Chinese Pharmacological Society

(2016) Zhi-Kang Ye et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Pharmacist-managed dose adjustment feedback using therapeutic drug monitoring of vancomycin was useful for patients with methicillin-resistant Staphylococcus aureus infections: a single institution experience

(2016) Ryuichi Hirano et al.   Infection and Drug Resistance

PBPK modeling and simulation in drug research and development

(2016) Xiaomei Zhuang et al.   Acta Pharmaceutica Sinica B

Review of vancomycin-induced renal toxicity: an update

(2016) Oluwatoyin Bamgbola   Therapeutic Advances in Endocrinology and Metabolism

p53 activates miR-192-5p to mediate vancomycin induced AKI

(2016) Jinwen Chen et al.   Scientific Reports

Implementing Toxicity Testing in the 21st Century (TT21C): Making safety decisions using toxicity pathways, and progress in a prototype risk assessment

(2015) Yeyejide Adeleye et al.   TOXICOLOGY

Protective Effects of Cilastatin against Vancomycin-Induced Nephrotoxicity

(2015) Blanca Humanes et al.   Biomed Research International

Reduced susceptibility to vancomycin and biofilm formation in methicillin-resistant Staphylococcus epidermidis isolated from blood cultures

(2014) Luiza Pinheiro et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Kindlin-2 Mediates Activation of TGF- /Smad Signaling and Renal Fibrosis

(2013) X. Wei et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Lysophosphatidylcholine-induced cytotoxicity in osteoblast-like MG-63 cells: Involvement of transient receptor potential vanilloid 2 (TRPV2) channels

(2013) Abdallah Fallah et al.   MOLECULAR MEMBRANE BIOLOGY

Novel physiologically based pharmacokinetic modeling of patupilone for human pharmacokinetic predictions

(2012) Binfeng Xia et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Mitochondrial superoxide production contributes to vancomycin-induced renal tubular cell apoptosis

(2012) Yohei Arimura et al.   FREE RADICAL BIOLOGY AND MEDICINE

Interspecies Modeling and Prediction of Human Exenatide Pharmacokinetics

(2012) Ting Chen et al.   PHARMACEUTICAL RESEARCH

Mechanisms of lysophosphatidylcholine-induced hepatocyte lipoapoptosis

(2011) Keisuke Kakisaka et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Physiologically-Based Pharmacokinetics in Drug Development and Regulatory Science

(2011) Malcolm Rowland et al.   Annual Review of Pharmacology and Toxicology

Quantitative Prediction of Human Pharmacokinetics for Monoclonal Antibodies

(2011) Jennifer Q. Dong et al.   CLINICAL PHARMACOKINETICS

Serum and kidney metabolic changes of rat nephrotoxicity induced by Morning Glory Seed

(2010) Chao Ma et al.   FOOD AND CHEMICAL TOXICOLOGY

Toxicology effects of Morning Glory Seed in rat: A metabonomic method for profiling of urine metabolic changes

(2010) Chao Ma et al.   JOURNAL OF ETHNOPHARMACOLOGY

Defining the Role of Macrophages in Local Moxifloxacin Tissue Concentrations using Biopsy Data and Whole-Body Physiologically Based Pharmacokinetic Modelling

(2009) Andrea N. Edginton et al.   CLINICAL PHARMACOKINETICS

Lysophospholipid signaling: Beyond the EDGs

(2007) William J. Valentine et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS