Effective inhibition of PBPs by cefepime and zidebactam in the presence of VIM-1 drives potent bactericidal activity against MBL-expressing Pseudomonas aeruginosa

Aztreonam plus clavulanate, tazobactam or avibactam for the treatment of metallo-β-lactamase-producing-Gram negative related infections

(2019) Cécile Emeraud et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In vitro and in vivo activity of β-lactams in combination with novel β-lactam enhancers, zidebactam and WCK 5153, against multidrug-resistant metallo-β-lactamase producing Klebsiella pneumoniae

(2019) Bartolome Moya et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Strategic Approaches to Overcome Resistance against Gram-Negative Pathogens Using β-Lactamase Inhibitors and β-Lactam Enhancers: Activity of Three Novel Diazabicyclooctanes WCK 5153, Zidebactam (WCK 5107), and WCK 4234

(2018) Krisztina M. Papp-Wallace et al.   JOURNAL OF MEDICINAL CHEMISTRY

Assessment of the In Vivo Efficacy of WCK 5222 (Cefepime-Zidebactam) Against Carbapenem-Resistant Acinetobacter baumannii in the Neutropenic Murine Lung Infection Model

(2018) Lindsay M. Avery et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

WCK 5222 (cefepime/zidebactam) antimicrobial activity tested against Gram-negative organisms producing clinically relevant β-lactamases

(2017) Helio S. Sader et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

In vitro activity of cefepime/zidebactam (WCK 5222) against Gram-negative bacteria

(2017) David M. Livermore et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Spotlight on ceftazidime/avibactam: a new option for MDR Gram-negative infections

(2016) Marco Falcone et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Biochemical, Mechanistic, and Spectroscopic Characterization of Metallo-β-lactamase VIM-2

(2014) Mahesh Aitha et al.   BIOCHEMISTRY

Carbapenemases in Gram-Negative Bacteria: Laboratory Detection and Clinical Significance

(2014) Branka Bedenić et al.   Biomed Research International

Emerging carbapenemases: a global perspective

(2010) Timothy R. Walsh   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Characterization of the New Metallo- -Lactamase VIM-13 and Its Integron-Borne Gene from a Pseudomonas aeruginosa Clinical Isolate in Spain

(2008) C. Juan et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY